Results 31 to 40 of about 60,784 (278)
The centrosome and mitotic spindle apparatus in cancer and senescence [PDF]
Cell Cycle, 2010 Altered cell division is associated with overproliferation and tumorigenesis, however, mitotic aberrations can also trigger antiproliferative responses leading to postmitotic cell cycle exit. Here, we focus on the role of the centrosome and in particular of centrosomal TACC (transforming acidic coiled coil) proteins in tumorigenesis and cellular ...
Stephen, Schmidt +13 more
openaire +2 more sources
A regulatory effect of INMAP on centromere proteins: antisense INMAP induces CENP-B variation and centromeric halo. [PDF]
PLoS ONE, 2014 CENP-B is a highly conserved protein that facilitates the assembly of specific centromere structures both in interphase nuclei and on mitotic chromosomes. INMAP is a conserved protein that localizes at nucleus in interphase cells and at mitotic apparatus
Tan Tan +4 more
doaj +1 more source
Dominant-Negative Effects of Adult-Onset Huntingtin Mutations Alter the Division of Human Embryonic Stem Cells-Derived Neural Cells. [PDF]
PLoS ONE, 2016 Mutations of the huntingtin protein (HTT) gene underlie both adult-onset and juvenile forms of Huntington's disease (HD). HTT modulates mitotic spindle orientation and cell fate in mouse cortical progenitors from the ventricular zone.
Carla Lopes +7 more
doaj +1 more source
, 2016 Anaphase B spindle elongation is characterized by the sliding apart of overlapping antiparallel interpolar (ip) microtubules (MTs) as the two opposite spindle poles separate, pulling along disjoined sister chromatids, thereby contributing to chromosome ...
Brust-Mascher, Ingrid +2 more
core +2 more sources
Two major autoantigen—Antibody systems of the mitotic spindle apparatus [PDF]
Arthritis & Rheumatism, 1996 AbstractObjective. To characterize human autoantigen‐antibody systems related to the mitotic poles and spindles.Methods. Thirty‐seven human sera with autoantibodies staining mitotic poles and spindles in indirect immunofluorescence (IIF) studies were further characterized by immunofluorescence on mitotic cells and by immunoblotting and ...
L E, Andrade +3 more
openaire +2 more sources
European Journal of Cell Biology, 2022 To understand general features in evolution of kinetochore organization, investigating a wide range of mitotic mechanisms in various non-model eukaryotes is necessary.
Pavla Tůmová +2 more
doaj +1 more source
DSK1, a novel kinesin-related protein from the diatom Cylindrotheca fusiformis that is involved in anaphase spindle elongation. [PDF]
, 1996 We have identified an 80-kD protein that is involved in mitotic spindle elongation in the diatom Cylindrotheca fusiformis. DSK1 (Diatom Spindle Kinesin 1) was isolated using a peptide antibody raised against a conserved region in the motor domain of the ...
Brady, B +3 more
core +2 more sources
Autoantibodies to the mitotic spindle apparatus in Mycoplasma pneumoniae disease [PDF]
Infection and Immunity, 1988 Antibodies to the mitotic spindle apparatus (MS) have been detected in only a very few patient sera studied for antinuclear antibodies by routine screening (G. A. McCarty, D. W. Velencia, and M. J. Fritzler, J. Rheumatol. 11:213-218, 1984). We found anti-MS antibodies to be quite common in sera from patients with Mycoplasma pneumoniae, especially in ...
K, Lind, M, Høier-Madsen, A, Wiik
openaire +2 more sources
Frontiers in Marine Science, 2021 Fertilized Zhikong scallop (Chlamys farreri) eggs were treated with cytochalasin B (CB 0.5 mg/L) at 14–15 min postfertilization to inhibit first polar body formation.
Yongren Li +3 more
doaj +1 more source
Microtubule and Actin Cytoskeletal Dynamics in Male Meiotic Cells of Drosophila melanogaster
Cells, 2022 Drosophila dividing spermatocytes offer a highly suitable cell system in which to investigate the coordinated reorganization of microtubule and actin cytoskeleton systems during cell division of animal cells.
Anna Frappaolo +2 more
doaj +1 more source