Autoantibodies to the mitotic spindle apparatus in Mycoplasma pneumoniae disease [PDF]
Antibodies to the mitotic spindle apparatus (MS) have been detected in only a very few patient sera studied for antinuclear antibodies by routine screening (G. A. McCarty, D. W. Velencia, and M. J. Fritzler, J. Rheumatol. 11:213-218, 1984). We found anti-MS antibodies to be quite common in sera from patients with Mycoplasma pneumoniae, especially in ...
K, Lind, M, Høier-Madsen, A, Wiik
openaire +2 more sources
The CeCDC-14 phosphatase is required for cytokinesis in the Caenorhabditis elegans embryo [PDF]
In all eukaryotic organisms, the physical separation of two nascent cells must be coordinated with chromosome segregation and mitotic exit. In Saccharomyces cerevisiae and Schizosaccharomyces pombe this coordination depends on a number of genes that ...
Erich A. Nigg +15 more
core +1 more source
Disjunction of conjoined twins: Cdk1, Cdh1 and separation of centrosomes
Accurate transmission of chromosomes from parent to progeny cell requires assembly of a bipolar spindle. Centrosomes (spindle pole body in yeast) are critical for the biogenesis of this complex mitotic apparatus since they confer bipolarity on the ...
Surana Uttam, Crasta Karen
doaj +1 more source
CKAP2 ensures chromosomal stability by maintaining the integrity of microtubule nucleation sites. [PDF]
Integrity of the microtubule spindle apparatus and intact cell division checkpoints are essential to ensure the fidelity of distributing chromosomes into daughter cells.
Chanelle M Case +6 more
doaj +1 more source
Aflatoxin B1 exposure disrupts organelle distribution in mouse oocytes [PDF]
Aflatoxin B1 (AFB1) is a secondary metabolite produced by the fungus Aspergillus, which is ubiquitous in moldy grain products. Aflatoxin B1 has been reported to possess hepatotoxicity, renal toxicity, and reproductive toxicity.
Yan-Zhe Zhang +5 more
doaj +2 more sources
Bacteria spring a surprise [PDF]
Cell division involves the precise duplication of all the genetic material in the cell—both the chromosomes and the plasmid DNA—and the equal division of this material between the two daughter cells.
Srinivasan, Rajagopalan +3 more
core +1 more source
Morphogenetic forces planar polarize LGN/Pins in the embryonic head during Drosophila gastrulation
Spindle orientation is often achieved by a complex of Partner of Inscuteable (Pins)/LGN, Mushroom Body Defect (Mud)/Nuclear Mitotic Apparatus (NuMa), Gαi, and Dynein, which interacts with astral microtubules to rotate the spindle.
Jaclyn Camuglia +2 more
doaj +1 more source
Effect of DHEA and metformin on the spindle apparatus of MII oocytes. [PDF]
Figure A1–3 shows the representative images of normal spindle apparatus. Abnormal spindle apparatus was characterized by dispersed spindles and chromosomes (B1–3) and abnormal spindle shapes (C1–3) (Bar is 20μm).
Yue Zhao (186573) +7 more
core +1 more source
A regulatory effect of INMAP on centromere proteins: antisense INMAP induces CENP-B variation and centromeric halo. [PDF]
CENP-B is a highly conserved protein that facilitates the assembly of specific centromere structures both in interphase nuclei and on mitotic chromosomes. INMAP is a conserved protein that localizes at nucleus in interphase cells and at mitotic apparatus
Tan Tan +4 more
doaj +1 more source
Spindle birefringence of isolated mitotic apparatus: further evidence for two birefringent spindle components [PDF]
ABSTRACT We studied sea-urchin zygote mitotic apparatus (MA) isolated in hexylene glycol, transferred immediately to a glycerol-dimethylsulphoxide medium, and stored for 2 weeks at room temperature. Treatment with 0·5 M KC1 caused loss of 45% of the birefringence, but microtubules remained intact (as seen electron microscopically in ...
A, Forer, V I, Kalnins, A M, Zimmerman
openaire +2 more sources

