Results 31 to 40 of about 402,652 (266)

Uncovering the molecular machinery of the human spindle--an integration of wet and dry systems biology.

PLoS ONE, 2012
The mitotic spindle is an essential molecular machine involved in cell division, whose composition has been studied extensively by detailed cellular biology, high-throughput proteomics, and RNA interference experiments.
Ana M Rojas, Anna Santamaria, Rainer Malik, Thomas Skøt Jensen, Roman Körner, Ian Morilla, David de Juan, Martin Krallinger, Daniel Aaen Hansen, Robert Hoffmann, Jonathan Lees, Adam Reid, Corin Yeats, Anja Wehner, Sabine Elowe, Andrew B Clegg, Søren Brunak, Erich A Nigg, Christine Orengo, Alfonso Valencia, Juan A G Ranea   +20 more
doaj   +1 more source

The association between muscle architecture and muscle spindle abundance

Scientific Reports, 2023
Across the human body, skeletal muscles have a broad range of biomechanical roles that employ complex proprioceptive control strategies to successfully execute a desired movement.
Roger W. P. Kissane, James P. Charles, Robert W. Banks, Karl T. Bates   +3 more
doaj   +1 more source

The centrosome and mitotic spindle apparatus in cancer and senescence [PDF]

Cell Cycle, 2010
Altered cell division is associated with overproliferation and tumorigenesis, however, mitotic aberrations can also trigger antiproliferative responses leading to postmitotic cell cycle exit. Here, we focus on the role of the centrosome and in particular of centrosomal TACC (transforming acidic coiled coil) proteins in tumorigenesis and cellular ...
Stephen, Schmidt, Frank, Essmann, Ion C, Cirstea, Fabian, Kuck, Harish C, Thakur, Madhurendra, Singh, Anja, Kletke, Reiner U, Jänicke, Constanze, Wiek, Helmut, Hanenberg, M Reza, Ahmadian, Klaus, Schulze-Osthoff, Bernd, Nürnberg, Roland P, Piekorz   +13 more
openaire   +2 more sources

Length-dependent anisotropic scaling of spindle shape [PDF]

, 2014
Spindle length varies dramatically across species and during early development to segregate chromosomes optimally. Both intrinsic factors, such as regulatory molecules, and extrinsic factors, such as cytoplasmic volume, determine spindle length scaling ...
Sébastien Besson, Sarah Young, Welburn, Julie P I, Julie P. I. Welburn, Young, Sarah, Besson, Sébastien   +5 more
core   +1 more source

Bub3p facilitates spindle checkpoint silencing in fission yeast [PDF]

, 2009
Although critical for spindle checkpoint signaling, the role kinetochores play in anaphase promoting complex (APC) inhibition remains unclear. Here we show that spindle checkpoint proteins are severely depleted from unattached kinetochores in fission ...
Hardwick, Kevin G., Millar, Jonathan B.A., van der Sar, Sjaak J. A., van der Sar, Sjaak J A, van Der Sar, Sjaak J.A., Millar, Jonathan B. A., Vanoosthuyse, Vincent, Millar, Jonathan B A, Meadows, John C, Vanoosthuyse, V., Hardwick, Kevin, Meadows, John, Meadows, John C., Hardwick, Kevin G   +13 more
core   +1 more source

Effects of pentoxifylline on mouse oocytes maturation and qualityin vitro [PDF]

Iranian Journal of Basic Medical Sciences
Objective(s): To investigate the impact of Pentoxifylline (PTX) on the in vitro maturation (IVM) of mouse oocytes and its effect on oocyte quality.Materials and Methods: This experimental study involved culturing mouse oocytes in an IVM medium with ...
Wu Junjiao, Wu Jianbo, Yanyan Xu
doaj   +1 more source

The spindle matrix protein, Chromator, is a novel tubulin binding protein that can interact with both microtubules and free tubulin. [PDF]

PLoS ONE, 2014
The chromodomain protein, Chromator, is localized to chromosomes during interphase; however, during cell division together with other nuclear proteins Chromator redistributes to form a macro molecular spindle matrix complex that embeds the microtubule ...
Changfu Yao, Chao Wang, Yeran Li, Yun Ding, Uttama Rath, Saheli Sengupta, Jack Girton, Kristen M Johansen, Jørgen Johansen   +8 more
doaj   +1 more source

Suppression of period doubling chetter in high-speed milling by spindle speed variation [PDF]

, 2011
Spindle speed variation is a well known technique to suppress regenerative machine tool vibra- tions, but it is usually considered to be effective only for low spindle speeds.
Arnaud, Lionel, Tamás Insperger, Lionel Arnaud, Grégoire Peigné, Insperger, Tamás, Sébastien Seguy, Peigné, Grégoire, Seguy, Sébastien, Dessein, Gilles, Gilles Dessein   +9 more
core   +1 more source

A newly conceived cylinder measuring machine and methods that eliminate the spindle errors [PDF]

, 2012
Advanced manufacturing processes require improving dimensional metrology applications to reach a nanometric accuracy level. Such measurements may be carried out using conventional highly accurate roundness measuring machines.
David, Jean Marie, GIBARU, Olivier, DAVID, Jean-Marie, NOUIRA, H, VISSIERE, Alain, NOUIRA, Hichem, DAMAK, Mohamed   +6 more
core   +1 more source

Disjunction of conjoined twins: Cdk1, Cdh1 and separation of centrosomes

Cell Division, 2006
Accurate transmission of chromosomes from parent to progeny cell requires assembly of a bipolar spindle. Centrosomes (spindle pole body in yeast) are critical for the biogenesis of this complex mitotic apparatus since they confer bipolarity on the ...
Surana Uttam, Crasta Karen
doaj   +1 more source