Results 11 to 20 of about 60,784 (278)
ASSOCIATION BETWEEN THE SPINDLE APPARATUS AND REOVIRUS [PDF]
openaire +4 more sources
Genetic Disorders Affecting Tubulin Cytoskeleton [PDF]
The tubulin cytoskeleton is vital for maintenance and dynamics of eukaryotic cells and molecular defects in its components can lead to serious conditions.
Maya Markova +5 more
doaj +3 more sources
A Balance between Nuclear and Cytoplasmic Volumes Controls Spindle Length. [PDF]
Proper assembly of the spindle apparatus is crucially important for faithful chromosome segregation during anaphase. Thanks to the effort over the last decades, we have very detailed information about many events leading to spindle assembly and ...
Lucia Novakova +5 more
doaj +1 more source
USP11 deubiquitinates RAE1 and plays a key role in bipolar spindle formation. [PDF]
Correct segregation of the mitotic chromosomes into daughter cells is a highly regulated process critical to safeguard genome stability. During M phase the spindle assembly checkpoint (SAC) ensures that all kinetochores are correctly attached before its ...
Anna Stockum +2 more
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Background Ral family is a member of Ras-like GTPase superfamily, which includes RalA and RalB. RalA/B play important roles in many cell biological functions, including cytoskeleton dynamics, cell division, membrane transport, gene expression and signal ...
Ming-Hong Sun +7 more
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The association between muscle architecture and muscle spindle abundance
Across the human body, skeletal muscles have a broad range of biomechanical roles that employ complex proprioceptive control strategies to successfully execute a desired movement.
Roger W. P. Kissane +3 more
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A spindle-like apparatus guides bacterial chromosome segregation [PDF]
Until recently, a dedicated mitotic apparatus that segregates newly replicated chromosomes into daughter cells was believed to be unique to eukaryotic cells. Here we demonstrate that the bacterium Caulobacter crescentus segregates its chromosome using a partitioning (Par) apparatus that has surprising similarities to eukaryotic spindles.
Jerod L, Ptacin +7 more
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Mechanisms of spindle bipolarity establishment in acentrosomal human cells
Centrosomes are not absolutely essential for cell division; acentrosomal bipolar spindles can be established in oocytes and centrosome-eliminated somatic cells.
Kaho Hashimoto +2 more
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Spindle birefringence of isolated mitotic apparatus: further evidence for two birefringent spindle components [PDF]
ABSTRACT We studied sea-urchin zygote mitotic apparatus (MA) isolated in hexylene glycol, transferred immediately to a glycerol-dimethylsulphoxide medium, and stored for 2 weeks at room temperature. Treatment with 0·5 M KC1 caused loss of 45% of the birefringence, but microtubules remained intact (as seen electron microscopically in ...
A, Forer, V I, Kalnins, A M, Zimmerman
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The mitotic spindle is an essential molecular machine involved in cell division, whose composition has been studied extensively by detailed cellular biology, high-throughput proteomics, and RNA interference experiments.
Ana M Rojas +20 more
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