Mechanisms of spindle bipolarity establishment in acentrosomal human cells [PDF]
Molecular & Cellular Oncology, 2020 Centrosomes are not absolutely essential for cell division; acentrosomal bipolar spindles can be established in oocytes and centrosome-eliminated somatic cells.
Kaho Hashimoto +2 more
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A Balance between Nuclear and Cytoplasmic Volumes Controls Spindle Length. [PDF]
PLoS ONE, 2016 Proper assembly of the spindle apparatus is crucially important for faithful chromosome segregation during anaphase. Thanks to the effort over the last decades, we have very detailed information about many events leading to spindle assembly and ...
Lucia Novakova +5 more
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The novel BTB-kelch protein, KBTBD8, is located in the Golgi apparatus and translocates to the spindle apparatus during mitosis [PDF]
Cell Division, 2013 Abstract Proteins of the BTB-kelch family are known to be involved in multiple biological processes such as migration, cytoskeleton arrangement, regulation of cell morphology, protein ubiquitination and gene expression. KBTBD8 is a new member of this family.
Luehrig, Sandra +3 more
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Uncovering the molecular machinery of the human spindle--an integration of wet and dry systems biology. [PDF]
PLoS ONE, 2012 The mitotic spindle is an essential molecular machine involved in cell division, whose composition has been studied extensively by detailed cellular biology, high-throughput proteomics, and RNA interference experiments.
Ana M Rojas +20 more
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Microtubule capture by the cleavage apparatus is required for proper spindle positioning in yeast [PDF]
Genes & Development, 2002 Cell division is the result of two major cytoskeletal events: partition of the chromatids by the mitotic spindle and cleavage of the cell by the cytokinetic apparatus. Spatial coordination of these events ensures that each daughter cell inherits a nucleus. Here we show that, in budding yeast, capture and shrinkage of astral microtubules at the bud neck
Justine, Kusch +3 more
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β-tubulin phosphorylation by Chk1 is required for normal spindle formation during cell division [PDF]
Communications BiologyThe mitotic spindle is a microtubule-based apparatus that is responsible for accurate segregation of chromosomes into two daughter cells. In this study, we show that the DNA damage kinase Chk1 is required for optimal density and efficient nucleation of ...
Nikos Boutakoglou +7 more
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A nuclear-derived proteinaceous matrix embeds the microtubule spindle apparatus during mitosis [PDF]
Molecular Biology of the Cell, 2012 The concept of a spindle matrix has long been proposed. Whether such a structure exists, however, and what its molecular and structural composition are have remained controversial. In this study, using a live-imaging approach in Drosophila syncytial embryos, we demonstrate that nuclear proteins reorganize during mitosis to form a highly dynamic ...
Yao, Changfu +6 more
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ASSOCIATION BETWEEN THE SPINDLE APPARATUS AND REOVIRUS [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 1963 Dales Samuel, S Dales, Samuel Dales
exaly +3 more sources
Rare Antinuclear Antibody Patterns: Relevance in Routine Laboratory Reporting [PDF]
Journal of Clinical and Diagnostic Research, 2023 Introduction: Uncommon patterns on Human Epithelial 2 (Hep 2) substrate during Antinuclear Antibody (ANA) screening by Indirect Immunofluorescence (IIF) microscopy are not routinely reported by many laboratories since their clinical relevance is not well
Vidya Bhakta
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Evidence for spindle apparatus in somatic nuclei [PDF]
Fungal Genetics Reports, 1971 Evidence for spindle apparatus in somatic ...
W. B. Van Winkle, Van Winkle, W. B.
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