Results 91 to 100 of about 42,556 (266)

Microtubule-associated protein 1B (MAP1B) is required for dendritic spine development and synaptic maturation

, 2021
Microtubule-associated protein 1B (MAP1B) is prominently expressed during early stages of neuronal development, and it has been implicated in axonal growth and guidance.
Montenegro-Venegas, Carolina, Esteban, José A., Tortosa, Elena, Benoist, Marion, González-Billault, Christian, Ávila, Jesús, Härtel, Steffen   +6 more
core   +1 more source

An Accessible Microfluidic Platform for the Generation of Polarized Brain Organoids

Advanced Materials Technologies, EarlyView.
This study presents an accessible double‐gradient microfluidic device that enables controlled morphogen delivery and spatially polarized differentiation in brain organoids. By integrating a pump‐free design and stable fabrication method, the platform generates dorsal–ventral neuronal asymmetry, offering a reproducible and versatile approach to model ...
Daniel Pérez‐Calixto, Manuel Alejandro Vazquez Valle, Mitzi Pérez‐Calixto, Cindy Peto‐Gutiérrez, Iván Velasco, Genaro Vázquez‐Victorio, Itzel Escobedo‐Avila   +6 more
wiley   +1 more source

Palmitoylation of cdc42 Promotes Spine Stabilization and Rescues Spine Density Deficit in a Mouse Model of 22q11.2 Deletion Syndrome

, 2016
Palmitoylation of cdc42 Promotes Spine Stabilization and Rescues Spine Density Deficit in a Mouse Model of 22q11.2 Deletion Syndrome. 22q11.2 deletion syndrome (22q11DS) is associated with learning and cognitive dysfunctions and a high risk of developing
Muller, D., Nikonenko, Iryna, Wirth, A., Stefanelli, T., Moutin, Enora, Muller, Dominique, de Roo, M., De Roo, Mathias, Stefanelli, Thomas, Ponimaskin, E., Moutin, E., Nikonenko, I.   +11 more
core   +1 more source

Energy integration describes sound-intensity coding in an insect auditory system [PDF]

, 2002
We investigate the transduction of sound stimuli into neural responses and focus on locust auditory receptor cells. As in other mechanosensory model systems, these neurons integrate acoustic inputs over a fairly broad frequency range.
Andreas V. M. Herz, Gollisch, Tim, Schütze, Hartmut, Benda, Jan, Jan Benda, Herz, Andreas V. M., Hartmut Schütze, Tim Gollisch   +7 more
core   +1 more source

Bamboo Medical Application: A State‐of‐the‐Art Review

Advanced Materials Technologies, EarlyView.
This review presents a structured classification of bamboo's current use in healthcare. It organizes applications into medical textiles and medical devices, with further divisions based on function and level of invasiveness. It also examines material utilization based on bamboo's structural role, highlighting how it supports both protective and ...
Haymanot Beza Lamesgin, Koosje van der Stoel, Vera Popovich, Paul Breedveld   +3 more
wiley   +1 more source

Nonlocomotory Robotic Strategies for Dynamic Rotation Control in Terrestrial Robots: A Review

Advanced Robotics Research, EarlyView.
Terrestrial robots increasingly require rapid body rotation to maintain stability and agility in complex environments. This review shows nonlocomotory rotational control strategies that operate without ground contact, including reaction wheels, tails, bars, limbs, and thrusters.
Y. Liang, J. An, X. Zheng, D. Wang, S. Wang, X. Wang, P. Zhu, J. Pei, S. Li, J. Paripurana, Y. Han, Z. Tang, X. Gan, Q. He, X. Ma   +14 more
wiley   +1 more source

Antibiotics should not be used for back/leg pain

Acta Orthopaedica, 2021
Manniche Claus, Peter Fritzell, Olle Hägg, Tomas Bergström, Bodil Jönsson, Siv G E Andersson, Mikael Skorpil, Peter Muhareb Udby, Mikkel Andersen   +8 more
doaj   +1 more source

Triclabendazole inhibits PKM2 nuclear localization and glycolysis by enhancing HDAC6-mediated deacetylation in lung cancer

Journal of Translational Medicine
Background Metabolic reprogramming is a hallmark of cancer cells, enabling them to meet the heightened energetic and biosynthetic demands required for rapid growth and proliferation.
Liang Yan, Yong Sun, Shan-shan Shi, Yuan Li, Yi-fan Zhang, Liang-zhuo Qu, Jing Liu, Yong Dai, Qing-bing Zha, Jun Fan   +9 more
doaj   +1 more source

Strategic Design of Soft Actuators in Translational Medical Robotics for Human‐Centered Healthcare

Advanced Robotics Research, EarlyView.
Soft robotics enables biocompatible, compliant medical devices, but clinical translation requires design‐driven engineering beyond materials. This perspective reviews implantable, surgical, and wearable systems by actuation mechanism, highlighting how optimized architectures and integration improve mechanical interfacing, adaptability, and durability ...
Ho Jun Jin, Jimin Kim, Inho Kim, Bong Hoon Kim   +3 more
wiley   +1 more source

GPR124 Alleviates Blood–Brain Barrier Disruption by Enhancing Microvascular Endothelial Function after Traumatic Brain Injury

Advanced Science, EarlyView.
Our study reveals the protective role of GPR124 in maintaining BBB integrity and promoting neurological recovery following TBI. It makes a significant contribution by uncovering a novel molecular interaction between GPR124 and FGFBP1 and linking this to activation of the Wnt/β‐catenin signaling pathway in vascular repair mechanisms.
Chen Wang, Lin Cai, Qiuyuan Gong, Yang Yang, Yuqing Liang, Xinyu Niu, Lai Wei, Ze Liu, Shengju Wu, Yinghui Men, Yaohui Tang, Jun Ding, Hengli Tian, Hao Chen   +13 more
wiley   +1 more source