Results 111 to 120 of about 1,782,642 (314)

Get Ready for 100 Years of Active Spine Life Using Percutaneous Endoscopic Spine Surgery (PESS) [PDF]

open access: yes, 2018
Lumbar spinal stenosis is the most common indication for spinal surgery in patients older than 65 years. After the introduction of Kambin's safety triangle, percutaneous endoscopic spine surgery has started through transforaminal approach for discectomy ...
Nitin Adsul   +5 more
core   +2 more sources

Dysbiosis of Gut Microbiota in Ankylosing Spondylitis Patients

open access: yesJournal of Inflammation Research
Lianjun Yang,1,* Kun Wang,1,* Bin Liu,2,* Tao Chen,1 Tao Ma,3 Zhifei Cui,1 Dawei Zhang,1 Shiyanjin Zhang,1 Xiang Liu,1 Jun Shen,4,5 Hai Lu1 1Department of Spine Surgery, The Fifth Affiliated Hospital, Sun Yat-Sen University ...
Yang L   +10 more
doaj  

Successful Treatment of Severe Occipitocervical Pain from C1-C2 Osteoarthritis Using a Modified Harms Technique

open access: yesGlobal Spine Journal, 2016
Introduction C1-C2 fusion with instrumentation is an established treatment for C1-C2 instability due to trauma or inflammatory disease. C1-C2 fusion for debilitating occipitocervical pain secondary to C1-C2 osteoarthritis has been reported in a small ...
Ara Deukmedjian   +3 more
doaj   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

open access: yesAdvanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters   +12 more
wiley   +1 more source

Life expectancy after lumbar spine surgery: one- to eleven-year follow-up of 1015 patients.

open access: yes, 2008
STUDY DESIGN: Retrospective study. OBJECTIVES: To investigate the 10-year survival of a large number of elderly patients who underwent spine surgery for lumbar spinal stenosis, and to identify significant risk factors and compare them with age- and ...
김호중   +5 more
core   +1 more source

A2AR regulate inflammation through PKA/NF-κB signaling pathways in intervertebral disc degeneration

open access: yesEuropean Journal of Medical Research
Background Reduction of inflammatory damage and inhibition of nucleus pulposus (NP) apoptosis are considered to be the main effective therapy idea to reverse the intervertebral disc degeneration (IDD) and alleviate the chronic low back pain.
Weijun Liu   +10 more
doaj   +1 more source

In Situ Stress‐Dispersing Hydrogel Millispheres via Load Redistribution to Restore Nucleus Pulposus Metabolic Homeostasis

open access: yesAdvanced Science, EarlyView.
Local stress concentration disrupts metabolic homeostasis and induces inflammation in the nucleus pulposus (NP), thereby accelerating intervertebral disc degeneration (IDD). A biomimetic HA/ChS hydrogel millimeter sphere (ChS@HM) is developed to enable synergistic stress dispersion and sustained hydration lubrication.
Ang Li   +4 more
wiley   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

open access: yesAdvanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing   +10 more
wiley   +1 more source

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

open access: yesAdvanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu   +10 more
wiley   +1 more source

A Retrospective Analysis of Surgical, Patient, and Clinical Characteristics Associated with Length of Stay Following Lumbar Spine Surgery

open access: yes, 2020
Background: Elective spine surgeries utilize significant hospital resources. Postoperative hospital length of stay (LOS) requires substantial nursing, nutritional, social, administrative, and overhead resources, thus contributing greatly to the costs of ...
Stevens, Madison
core  

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