Results 111 to 120 of about 138,981 (311)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak +4 more
wiley +1 more source
, 2017 This is an XLSX file with three sheets. The first contains the specimen numbers (field numbers only, as the specimens have not been accessioned), measurements, and regeneration status for all eucladid anal sac spines used in this study; the second ...
Carlton Brett (3369758) +7 more
core +1 more source
Multiple events lead to dendritic spine loss in triple transgenic Alzheimer's disease mice [PDF]
, 2010 The pathology of Alzheimer's disease (AD) is characterized by the accumulation of amyloid-β (Aβ) peptide, hyperphosphorylated tau protein, neuronal death, and synaptic loss.
Fuhrmann Martin +28 more
core +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec +6 more
wiley +1 more source
Structural plasticity of dendritic secretory compartments during LTP-induced synaptogenesis
eLife, 2019 Long-term potentiation (LTP), an increase in synaptic efficacy following high-frequency stimulation, is widely considered a mechanism of learning. LTP involves local remodeling of dendritic spines and synapses.
Yelena D Kulik +4 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan +5 more
wiley +1 more source
Lost Nutrition Differences Frozen Milkfish Non Whip Out Spines and Whip Out Spines During Low Storage [PDF]
, 2017 Freezing was one alternative way to maintain the quality of the fish. The purpose of this study was to determine the amount of nutrients lost from frozen fish drip non whip out spines and whip out spines on a long pull at different low storage ...
Kusuma, Arifiya Ayu +5 more
core +1 more source
Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket +14 more
wiley +1 more source
Electrical properties of dendritic spines
, 1983 Since the discovery of dendritic spines by Ramon y Cajal2, their functional role has remained a matter of speculation. The early hypotheses all consider the establishment of physical contacts with presynaptic terminals as the main function of spines.
Koch, C. +3 more
core +1 more source