Results 41 to 50 of about 27,684 (298)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Pocket-size microwave radiation hazard detector [PDF]

open access: yes, 1974
Inexpensive lightweight unit is easily carried in coat pocket or attached to belt, detector sounds alarm in presence of dangerous microwave radiation levels. Unit consists of antenna, detector, level sensor, keyed oscillator, and speaker.
Kolbly, R. B.
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

SUBWAVELENGTH SPIRAL SLOTTED WAVEGUIDE ANTENNA [PDF]

open access: yesProgress In Electromagnetics Research C, 2013
Integrating antennas into a load-bearing airframe structure has the potential for profound improvements in the capability of military and commercial airplanes, by allowing for substantially increased radiator and array size with reduced weight or drag penalties. Reducing the size of array elements can significantly improve the mechanical performance of
Ali Daliri   +5 more
openaire   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende   +26 more
wiley   +1 more source

Fabrication and Mathematical Modeling of SWCNT Scaffold DNA Spiral Nantenna [PDF]

open access: yes, 2015
DNA origami based spiral structure is synthesized to realize a nanoscale spiral antenna for biomedical applications. Single strand DNA (ssDNA) origami structures utilize self-assembly techniques and short ssDNA staples to develop the desired spiral ...
Alsharani, Ahmed   +4 more
core  

Understanding the Effect of Resistance Temperature Detector Temperature Controllers on Microstructural Alignment in Magnetic Freeze Casting

open access: yesAdvanced Engineering Materials, EarlyView.
The effect of temperature controllers that are commonly used in freeze‐casting is investigated in this work. Temperature controllers are observed to generate a voltage in the slurry. Microstructural alignment and ultimate compressive strength data show this voltage to interfere with the ability to align the microstructure using magnetic fields ...
Maddie A. Schmitz, Steven E. Naleway
wiley   +1 more source

Orbital angular momentum spectrum of antenna vortex beam based on loop integration

open access: yesAIP Advances, 2021
Due to the divergence characteristics of vortex microwaves, it is difficult to determine orbital angular momentum (OAM) orders through far fields, while the spiral spectrum analysis method based on the area integral of antenna near fields is complicated.
Guang Yang   +3 more
doaj   +1 more source

Manufacturing Continuous Fiber‐Reinforced Printing Filaments: Development of a Post‐Consolidation Unit

open access: yesAdvanced Engineering Materials, EarlyView.
A novel, temperature‐controlled post‐consolidation unit is developed to test its potential to improve the melt impregnation process used to manufacture continuous fiber‐reinforced filaments for additive manufacturing of high‐performance thermoplastics.
Daniel Beermann   +2 more
wiley   +1 more source

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