Results 181 to 190 of about 13,039 (280)

The role of stanniocalcin-1 in spiral artery remodelling

open access: yesPlacenta, 2016
Mazen, A   +3 more
openaire   +2 more sources

Coordinated regulation of PIEZO2 by alternative splicing, post‐translational modification, membrane trafficking and protein partners

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise   +2 more
wiley   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

open access: yesMedicinal Research Reviews, Volume 46, Issue 2, Page 475-512, March 2026.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova   +3 more
wiley   +1 more source

The Space Within: How Architected Voids Promote Tissue Formation

open access: yesAdvanced Materials, Volume 38, Issue 7, 2 February 2026.
This review explores the role of void spaces in tissue engineering scaffolds and examines four key methods for introducing porosity into hydrogels at different scales. It discusses sacrificial templating, microgels, phase separation, and 3D printing, highlighting principles, advantages, and limitations. It also addresses emerging strategies integrating
Anna Puiggalí‐Jou   +3 more
wiley   +1 more source

Bisphenol B Exposure Induces Miscarriage by Suppressing Migration/Invasion and Migrasome Formation

open access: yesAdvanced Science, Volume 13, Issue 7, 3 February 2026.
BPB (Bisphenol B) exposure up‐regulates ER (estrogen receptor) levels, enhances its interactions with the lnc‐HZ04 promoter region, and thus promotes ER‐mediated lnc‐HZ04 transcription. Subsequently, lnc‐HZ04 suppresses TCF4 (transcription factor 4)‐mediated PKCA (protein kinase C alpha) transcription and subsequently suppresses migration/invasion and ...
Wenxin Huang   +13 more
wiley   +1 more source

Interleukin‐1β Stimulates Matrix Metalloproteinase 10 Secretion: A Possible Mechanism in Trophoblast‐Dependent Spiral Artery Remodeling [PDF]

open access: hybrid
Holly Tinsley   +8 more
openalex   +1 more source

Large deletions in the DNA primase large subunit PRIM2 are associated with NADP‐malate dehydrogenase activity in a porcine F2 cross

open access: yesAnimal Genetics, Volume 57, Issue 1, February 2026.
Abstract Large porcine F2 crosses are a valuable resource for discovering QTL and genetic variants for relevant traits. Past studies have been largely limited to SNPs and short insertions and deletions. Structural variants (SVs) are becoming a major area of interest in this respect.
Clemens Falker‐Gieske   +6 more
wiley   +1 more source

Heat Therapy: Targeting Health, Disease, and Disability

open access: yesComprehensive Physiology, Volume 16, Issue 1, February 2026.
The predominance of evidence suggests heat therapy has an impact on all aspects of health and performance, but the drivers of that improvement, the extent to which they are improved, and the specific populations in which improvements manifest are far from completely understood.
Rauchelle E. Richey   +5 more
wiley   +1 more source

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