Results 11 to 20 of about 23,483 (241)

Inhibition of Trophoblast-Induced Spiral Artery Remodeling Reduces Placental Perfusion in Rat Pregnancy. [PDF]

, 2010
Rats harboring the human angiotensinogen and human renin genes develop preeclamptic features in pregnancy. The preeclamptic rats exhibit a deeper trophoblast invasion associated with a reduced resistance index by uterine Doppler.
Cartwright, JE, Davidge, ST, Dechend, R, Dudenhausen, JW, Geusens, N, Hering, L, Herse, F, Luft, FC, Morton, J, Muller, DN, Pijnenborg, R, Verhaegen, I, Verlohren, S   +12 more
core   +3 more sources

Maternal exposure to ambient PM2.5 causes fetal growth restriction via the inhibition of spiral artery remodeling in mice

Ecotoxicology and Environmental Safety, 2022
Background: Maternal exposure to ambient fine particulate matters (PM2.5) is associated with low birth weight (LBW) in offspring, but the underlying biological mechanisms are not yet fully understood.
Shimin Tao, Xuan Zhang, Fang Tian, Bin Pan, Renzhen Peng, Yuzhu Wang, Minjie Xia, Mingjun Yang, Jingying Hu, Haidong Kan, Yanyi Xu, Weihua Li   +11 more
doaj   +2 more sources

Trophoblast-induced changes in C-x-C motif chemokine 10 expression contribute to vascular smooth muscle cell dedifferentiation during spiral artery remodeling. [PDF]

, 2013
Objective- During pregnancy, fetal trophoblast disrupt endothelial cell and vascular smooth muscle cell (VSMC) interactions in spiral arteries of the maternal decidua to enable increased nutritional and oxygen delivery to the fetus.
Begum, R, Cartwright, JE, Laing, K, Thilaganathan, B, Wallace, AE, Whitley, GS   +5 more
core   +2 more sources

VE-cadherin enables trophoblast endovascular invasion and spiral artery remodeling during placental development

eLife, 2022
During formation of the mammalian placenta, trophoblasts invade the maternal decidua and remodel spiral arteries to bring maternal blood into the placenta.
Derek C Sung, Xiaowen Chen, Mei Chen, Jisheng Yang, Susan Schultz, Apoorva Babu, Yitian Xu, Siqi Gao, TC Stevenson Keller IV, Patricia Mericko-Ishizuka, Michelle Lee, Ying Yang, Joshua P Scallan, Mark L Kahn   +13 more
doaj   +2 more sources

Differences in lymphocyte subsets of spiral artery associated with impaired vascular remodeling in hypertensive disorders of pregnancy

BMC Pregnancy and Childbirth
Hypertensive disorders of pregnancy (HDP) is assumed to be triggered by incomplete remodeling of the decidual spiral arteries. We examined the lymphocyte subsets and identified immune differences in the spiral arteries between HDP and normal pregnancies,
Ayako Tateishi, Tsutomu Miyamoto, Maki Ohya, Tanri Shiozawa, Hiroyuki Kanno   +4 more
doaj   +2 more sources

Decidual natural killer cells regulate vessel stability: implications for impaired spiral artery remodelling. [PDF]

, 2015
Decidual NK (dNK) cells are present during uterine spiral artery remodelling, an event that is crucial for successful placentation and the provision of an adequate blood supply to the developing fetus.
Cartwright, JE, Fraser, R, Thilaganathan, B, Whitley, GS   +3 more
core   +2 more sources

Targeting A2M-LRP1 reverses uterine spiral artery remodeling disorder and alleviates the progression of preeclampsia

Cell Communication and Signaling
Background Patients with early-onset preeclampsia (EOPE) have a most severe disease state. a2-macroglobulin (A2M) play a crucial role in the pathogenesis of EOPE, but its molecular basis and therapeutic potential remain unclear.
Zhengrui Huang, Ping Zhang, Ruiping Chen, Lu Sun, Jingyun Wang, Ruiling Yan, Mengyuan Liu, Yuzhen Ding, Jian Wang, Jiachun Wei, Wanchang Yin, Xinyao Lu, Guang Wang, Xuesong Yang, Ruiman Li   +14 more
doaj   +2 more sources

Role of corin in trophoblast invasion and uterine spiral artery remodelling in pregnancy [PDF]

Nature, 2012
Yujie Cui, Ningzheng Dong, Dinesh Kumar Srinivasan   +2 more
exaly   +2 more sources

CT Diagnosis of Median Arcuate Ligament Compression Syndrome with Spontaneous Isolated Superior Mesenteric Artery Dissection: A Case Report

CT Lilun yu yingyong yanjiu, 2023
This article explores the CT findings and outcome of a case involving median arcuate ligament compression syndrome complicated with spontaneous isolated superior mesenteric artery dissection.
Xue HAN, Jinyong ZHAO, Zhaohui WANG, Dandan GENG   +3 more
doaj   +1 more source

Induced Human Decidual NK-Like Cells Improve Utero-Placental Perfusion in Mice. [PDF]

PLoS ONE, 2016
Decidual NK (dNK) cells, a distinct type of NK cell, are thought to regulate uterine spiral artery remodeling, a process that allows for increased blood delivery to the fetal-placental unit.
Ricardo C Cavalli, Ana Sofia Cerdeira, Elizabeth Pernicone, Henri A Korkes, Suzanne D Burke, Augustine Rajakumar, Ravi I Thadhani, Drucilla J Roberts, Manoj Bhasin, S Ananth Karumanchi, Hernan D Kopcow   +10 more
doaj   +1 more source