Results 11 to 20 of about 13,039 (280)

Leukemia Inhibitory Factor (LIF) Inhibition during Mid-Gestation Impairs Trophoblast Invasion and Spiral Artery Remodelling during Pregnancy in Mice. [PDF]

PLoS ONE, 2015
The placenta forms the interface between the maternal and fetal circulation and is critical for the establishment of a healthy pregnancy. Trophoblast cell proliferation, migration and invasion into the endometrium are fundamental events in the initiation
Amy Winship, Jeanne Correia, Jian-Guo Zhang, Nicos A Nicola, Evdokia Dimitriadis   +4 more
doaj   +3 more sources

Mitochondrial ROS Accumulation Contributes to Maternal Hypertension and Impaired Remodeling of Spiral Artery but Not IUGR in a Rat PE Model Caused by Maternal Glucocorticoid Exposure [PDF]

Antioxidants, 2023
Increased maternal glucocorticoid levels have been implicated as a risk factor for preeclampsia (PE) development. We found that pregnant rats exposed to dexamethasone (DEX) showed hallmarks of PE features, impaired spiral artery (SA) remodeling, and ...
Jing Long, Yan Huang, Gang Wang, Zhengshan Tang, Yali Shan, Shiping Shen, Xin Ni   +6 more
doaj   +2 more sources

Inhibition of Trophoblast-Induced Spiral Artery Remodeling Reduces Placental Perfusion in Rat Pregnancy. [PDF]

Hypertension, 2010
Rats harboring the human angiotensinogen and human renin genes develop preeclamptic features in pregnancy. The preeclamptic rats exhibit a deeper trophoblast invasion associated with a reduced resistance index by uterine Doppler.
Cartwright, JE, Davidge, ST, Dechend, R, Dudenhausen, JW, Geusens, N, Hering, L, Herse, F, Luft, FC, Morton, J, Muller, DN, Pijnenborg, R, Verhaegen, I, Verlohren, S   +12 more
core   +5 more sources

Uterine Spiral Artery Remodeling Involves Endothelial Apoptosis Induced by Extravillous Trophoblasts Through Fas/FasL Interactions [PDF]

, 2004
Objective— Invasion of uterine spiral arteries by extravillous trophoblasts in the first trimester of pregnancy results in loss of endothelial and musculoelastic layers.
Sandra Ashton, Guy Whitley, Philip R. Dash, Mark Wareing, Ian Crocker, Philip N. Baker, Judith E. Cartwright   +6 more
openalex   +3 more sources

Overexpression of miR-210-3p Impairs Extravillous Trophoblast Functions Associated with Uterine Spiral Artery Remodeling. [PDF]

Int J Mol Sci, 2021
Hayder H, Fu G, Nadeem L, O'Brien JA, Lye SJ, Peng C.   +5 more
europepmc   +3 more sources

Trophoblast-Induced Changes in C-X-C Motif Chemokine 10 Expression Contribute to Vascular Smooth Muscle Cell Dedifferentiation During Spiral Artery Remodeling [PDF]

, 2013
Objective- During pregnancy, fetal trophoblast disrupt endothelial cell and vascular smooth muscle cell (VSMC) interactions in spiral arteries of the maternal decidua to enable increased nutritional and oxygen delivery to the fetus.
Alison E. Wallace, Judith E. Cartwright, Runa Begum, Ken Laing, B. Thilaganathan, Guy Whitley   +5 more
openalex   +4 more sources

Differences in lymphocyte subsets of spiral artery associated with impaired vascular remodeling in hypertensive disorders of pregnancy [PDF]

BMC Pregnancy and Childbirth
Hypertensive disorders of pregnancy (HDP) is assumed to be triggered by incomplete remodeling of the decidual spiral arteries. We examined the lymphocyte subsets and identified immune differences in the spiral arteries between HDP and normal pregnancies,
Ayako Tateishi, Tsutomu Miyamoto, Maki Ohya, Tanri Shiozawa, Hiroyuki Kanno   +4 more
doaj   +2 more sources

Paradigms for investigating invasive trophoblast cell development and contributions to uterine spiral artery remodeling. [PDF]

Placenta, 2021
Varberg KM, Soares MJ.
europepmc   +3 more sources

Krüppel-like factor 17 upregulates uterine corin expression and promotes spiral artery remodeling in pregnancy. [PDF]

Proc Natl Acad Sci U S A, 2020
Wang C, Wang Z, He M, Zhou T, Niu Y, Sun S, Li H, Zhang C, Zhang S, Liu M, Xu Y, Dong N, Wu Q.   +12 more
europepmc   +3 more sources

Mechanosensing of Shear Stress and Uterine Spiral Artery Remodeling by Invasive Trophoblasts in Early Pregnancy. [PDF]

Int J Mol Sci
Szukiewicz D, Trojanowski S, Wróbel E, Wojdasiewicz P, Szewczyk G.   +4 more
europepmc   +3 more sources