Results 41 to 50 of about 35,436 (307)

Molluscs from a shallow-water whale-fall and their affinities with adjacent benthic communities on the Swedish west coast [PDF]

open access: yes, 2013
We conducted a species-level study of molluscs associated with a 5-m long carcass of a minke whale at a depth of 125 m in the Kosterfjord (North Sea, Sweden).
Dahlgren, TG   +3 more
core   +3 more sources

Simple approach to thieno[3,2-d]pyrimidines as new scaffolds of antimicrobial activities

open access: yesActa Pharmaceutica, 2016
6ʹ-(4-Chlorophenyl)-spiro[cyclohexane-1,2ʹ-thieno[3,2-d][1,3] oxazin]-4ʹ(1ʹH)-one (1) was synthesized and used as a starting material for the synthesis of a novel series of spiro compounds having biologically active sulfonamide 2a-e and 3ʹ-(4 ...
Hafez Hend N.   +2 more
doaj   +1 more source

Desing, synthesis and anti-inflammatory activity of dirivatives 10-R-3-aryl-6,7-dihydro-2H-[1,2,4]triazino[2,3-c]quinazolin-2-ones of spiro-fused cyclic frameworks

open access: yesActa Chimica Slovenica, 2017
Present work is devoted to the purposeful search of novel promising anti-inflammatory agents among the insufficiently known 3'-R-10'-R1-spiro[hetaryl-3(4),6'-[1,2,4]triazino[2,3-c]quinazolin]-2'(7'H)-ones.
Oleksandra Kolomoets   +7 more
doaj   +1 more source

Microbial Transformation of neo-Clerodane Diterpenoid, Scutebarbatine F, by Streptomyces sp. CPCC 205437

open access: yesFrontiers in Microbiology, 2021
Biotransformation of the neo-clerodane diterpene, scutebarbatine F (1), by Streptomyces sp. CPCC 205437 was investigated for the first time, which led to the isolation of nine new metabolites, scutebarbatine F1–F9 (2–10). Their structures were determined
Dewu Zhang   +8 more
doaj   +1 more source

Spiro heterocyclic compounds. VI. Synthesis of spiro(imidazolidine-4,1'-isoindoline) and related compounds.

open access: yesChemical and Pharmaceutical Bulletin, 1982
Nitrosation of 2-methylisoquinoline-1, 3 (2H, 4H)-dione (I) with NaNO2 in AcOH afforded the 4-nitroso compound (II) in almost quantitative yield. Catalytic reduction of II produced 4-imino-2-methylisoquinoline-1, 3 (2H, 4H)-dione (III) and a small amount of 4, 4'-bi-2-methylisoquinoline-1, 3 (2H, 4H)-dione (IV).
TAHARA, SACHIYO   +2 more
openaire   +2 more sources

Competitive formation of spiro and ansa derivatives in the reactions of tetrafluorobutane-1,4-diol with hexachlorocyclotriphosphazene: a comparison with butane-1,4-diol [PDF]

open access: yes, 2006
Reaction of hexachlorocyclotriphosphazene, N3P3Cl6 (1), in two stoichiometries (1:1.2 and 1:3) with the sodium derivative of the fluorinated diol, 2,2,3,3-tetrafluorobutane-1,4-diol, (2), in THF solution at room temperature afforded six products, whose ...
Beşli, S.   +5 more
core   +1 more source

Defining the Structural Consequences of Mechanism-Based Inactivation of Mammalian Cytochrome P450 2B4 Using Resonance Raman Spectroscopy [PDF]

open access: yes, 2010
In view of the potent oxidizing strength of cytochrome P450 intermediates, it is not surprising that certain substrates can give rise to reactive species capable of attacking the heme or critical distal-pocket protein residues to irreversibly modify the ...
Hollenberg, Paul F.   +3 more
core   +2 more sources

Synthesis of spiro quasi[1]catenanes and quasi[1]rotaxanes via a templated backfolding strategy

open access: yesNature Communications, 2017
Spiro compounds contain two or more rings linked together through one common atom. Here the authors provide a method to backfold both rings, producing spiro quasi[1]catenanes, via a strategy of temporarily linking the linear intermediates with covalent ...
Luuk Steemers   +4 more
doaj   +1 more source

(±)-Peniorthoesters A and B, Two Pairs of Novel Spiro-Orthoester en-antiomers With an Unusual 1,4,6-Trioxaspi-ro[4.5]decane-7-One Unit From Penicillium minioluteum

open access: yesFrontiers in Chemistry, 2018
(±)-Peniorthoesters A and B (±1 and ±2), two pairs of unprecedented spiro-orthoester enantiomers with a 1,4,6-trioxaspiro[4. 5]decane-7-one unit, were obtained from Penicillium minioluteum. Their structures were determined by spectroscopic methods, X-ray
Xiaorui Liu   +10 more
doaj   +1 more source

Spiro Cyclohexadienones from the Reaction of Phenolic Enaminone Derivatives with Hypervalent Iodine Reagents

open access: yesMolecules, 2000
Phenolic enamino compounds, prepared from 2-(4-hydroxyphenyl)-ethylamine and the corresponding β-keto carbonyl compounds, afford spiro cyclohexadienone derivatives on reaction with hypervalent iodine reagents.
Anastasios Varvoglis   +3 more
doaj   +1 more source

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