Synthesis and Characterization of New Spiroheterocyclic from Isatin and Evaluation of Some Their Antifungal and Antibacterial Activity [PDF]
مجلة جامعة الانبار للعلوم الصرفةSpiro compounds Spiro cycles are widely found in natural products, medicines, and functional materials[1] the spiro atom forces the planes of the two rings to almost face one another, spiro compounds are a desirable subclass of heterocyclic scaffolds. In
Zubaida Al-Heety, Ali Al-Nasseri
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Structural and stereogenic properties of spiro- and ansa-substituted 1,3-propanedioxy derivatives of a spermine-bridged cyclotriphosphazene [PDF]
, 2006 Reaction of 1,3-propanediol with the achiral spermine-bridged cyclophosphazene 1 at various molar ratios in THF gives a number of spiro-and ansa-derivatives that exhibit different stereogenic properties, viz. racemic, meso or achiral forms. As expected,
Adem Kılıç +29 more
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Molecules, 2023 The purpose of this work was to prepare new isatin- and monothiomalondiamide-based indole derivatives, as well as to study the properties of the new compounds.
Victor V. Dotsenko +5 more
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Larix decidua Bark as a Source of Phytoconstituents: An LC-MS Study [PDF]
, 2017 Larix decidua bark is a waste of the timber industry and is widely diffused in Northern Italy. This material can be considered a good source of antioxidants and phytoconstituents with possible use in cosmetic or nutraceutical products.
Baldan, Valeria +8 more
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Journal of Taibah University for Science, 2017 A new series of spiro-oxindoles that were identified based upon their ability to inhibit methionine tRNA synthase (PDB ID: 1PFV) and glucosamine-6-phosphate synthase (PDB ID: 1JXA) enzymes in virtual screening was synthesized by a three-component 1,3 ...
M. Sapnakumari +3 more
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An update on the synthesis and reactivity of spiro-fused β-lactams [PDF]
, 2018 Beta-Lactam ring-containing compounds play a pivotal role in drug design and synthetic chemistry. Spirocyclic beta-lactams, representing an important beta-lactam subclass, have recently attracted considerable interest with respect to new synthetic ...
D'hooghe, Matthias, Dao Thi, Hang
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Phenalene-phosphazene complexes: effect of exocyclic charge densities on the cyclotriphosphazene ring system [PDF]
, 1988 The synthesis and properties of a new series of 1,9-diamino-substituted phenalene complexes of the cyclotriphosphazene ring system is described. One of the compounds is shown to be amphoteric, and this behavior allows an examination of the response of ...
Chichester-Hicks, S. V. +2 more
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Stereoisomerism in pentaerythritol-bridged cyclotriphosphazene tri-spiranes: spiro and ansa 1,3-propanediyldioxy disubstituted derivatives [PDF]
, 2005 Four isomeric products were isolated and purified from the reaction of 1,3-propanediol with the tetra-spirane cyclophosphazene-organophosphate compound (1): viz. the di-monospiro (2a), di-monoansa (2b) and two monospiro-monoansa derivatives (2c) and (2d).
Aylin, U. +6 more
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Molecules, 2010 Homophthalic anhydride reacts with different aromatic amines to produce N-substituted homophthalimides. Bromination of the latter produces 4,4-dibromo-homophthalimide derivatives that can be used as precursors for spiro-derivatives.
Mohamed Mohamed Youssef +1 more
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Tetrahydropyrazolo[1,5-a]Pyrimidine-3-Carboxamide and N-Benzyl-6′,7′-Dihydrospiro[Piperidine-4,4′-Thieno[3,2-c]Pyran] analogues with bactericidal efficacy against Mycobacterium tuberculosis targeting MmpL3 [PDF]
, 2013 Mycobacterium tuberculosis is a major human pathogen and the causative agent for the pulmonary disease, tuberculosis (TB). Current treatment programs to combat TB are under threat due to the emergence of multi-drug and extensively-drug resistant TB.
A Hill +48 more
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