Results 101 to 110 of about 337 (160)
Hybrid macrocycle formation and spiro annulation on cis-syn-cis-tricyclo[6.3.0.0(2,6)]undeca-3,11-dione and its congeners via ring-closing metathesis. [PDF]
Kotha S, Chinnam AK, Ali R.
europepmc +1 more source
Design, Synthesis, Antifungal Evaluation, Structure-Activity Relationship (SAR) Study, and Molecular Docking of Novel Spirotryprostatin A Derivatives. [PDF]
Ma YM +5 more
europepmc +1 more source
Rh(III)-Catalyzed C8-Spiroannulation of 1-Aminonaphthalenes with Maleimides
The rhodium(III)-catalyzed C8-spiroannulation of 1-aminonaphthalenes with maleimides is described herein. Initially formed C8-alkenylated 1-aminonaphthalenes can intercept nucleophilic 1-amino groups through the intramolecular aza-Michael reaction, resulting in the formation of spirofused tetracyclic frameworks. This protocol displayed a wide substrate
Eunjae Chung +6 more
core +4 more sources
A dearomatization/spiroannulation process has been successfully achieved between simple halophenols and α,β-unsaturated olefins under mild reaction conditions. This transformation addresses the chemoselectivity issue in the dearomatizative transformation of phenol scaffolds (6π-electron) caused by the SEAr process, enabling the construction of ...
Sichan Dong +5 more
openaire +3 more sources
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Studies towards the diastereoselective spiroannulation of phenolic derivatives
Tetrahedron Letters, 2002AbstractFor Abstract see ChemInform Abstract in Full Text.
Guy L Plourde
exaly +2 more sources
Cyclic Ketones in Spiroannulation
Synthetic Communications, 2009Abstract Conversion of a cyclic carbonyl carbon into a quaternary carbon has been effected by a Wittig–Horner reaction with diethyl (N-benzyliden)aminomethylphosphonate and a subsequent alkylation with a protected vinyl ketone. The product was a substrate for spiroannulation after initial hydrolysis.
Vidar Bj⊘rnstad, Kjell Undheim
exaly +2 more sources
Prins-pinacol spiroannulations
Tetrahedron, 1997Abstract Lewis acid-promoted cyclizations of methylenecyclohexane siloxy acetals 14, 15 , and 21 afford spiro[4.5]decanones 22, 25 , and 29 in good yield. In all cases, exclusive pinacol rearrangement of C-1 of the original three-carbon acetal side chain is observed suggesting that pinacol rearrangement of the intermediate 9-decalyl cation ...
Keith P. Minor, Larry E. Overman
+4 more sources
Rhodium-Catalyzed Enantioselective Spiroannulation of 2-Alkenylphenols with Alkynes
Chinese Journal of Organic Chemistry, 2023Qing Gu
exaly +2 more sources

