Results 151 to 160 of about 61,341 (287)

Management and outcome of a dog with hepatic arteriovenous malformation and extensive thrombosis of splanchnic vessels (Canis lupus)

open access: yesVeterinary Record Case Reports, EarlyView.
Abstract This report describes the diagnosis, treatment and long‐term follow‐up of a dog with hepatic arteriovenous malformation and extensive thrombus of the splanchnic vessels. A 1‐year‐old, male, neutered golden retriever presented with haematochezia and ascites.
Yuqing Sun   +2 more
wiley   +1 more source

Spironolactone is an antagonist of NRG1‐ERBB4 signaling and schizophrenia‐relevant endophenotypes in mice

open access: yesEMBO Molecular Medicine, 2017
Enhanced NRG1‐ERBB4 signaling is a risk pathway in schizophrenia, and corresponding mouse models display several endophenotypes of the disease. Nonetheless, pathway‐directed treatment strategies with clinically applicable compounds have not been ...
Michael C Wehr   +15 more
doaj   +1 more source

Targeting efficacy of spironolactone in patients with heart failure with preserved ejection fraction: the TOPCAT study

open access: gold, 2022
Huimin Zhou   +11 more
openalex   +1 more source

The Roles of EDA2R in Ageing and Disease

open access: yesAging Cell, EarlyView.
Elevated expression of the ectodysplasin A2 receptor (EDA2R) has been linked to ageing and disease. We appraise the roles of EDA2R in these processes, exploring mechanisms of action, biomarker potential and therapeutic relevance of EDA2R in multiple contexts. ABSTRACT Ageing is a complex biological process driven, in part, by inflammaging.
Gemma Farrington   +9 more
wiley   +1 more source

Efficacy of low dose spironolactone in chronic kidney disease with resistant hypertension

open access: yesSaudi Journal of Kidney Diseases and Transplantation, 2011
To determine the antihypertensive benefit of adding low dose sprinolactone to multi-drug regimens that included a diuretic, a calcium channel blocker and angiotensin-converting enzyme inhibitor or angiotensin receptor blocker in patients with moderately ...
Rozita Abolghasmi, Omolbanin Taziki
doaj  

The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators.

open access: yesNew England Journal of Medicine, 1999
B. Pitt   +7 more
semanticscholar   +1 more source

Safety of low-dose spironolactone administration in chronic haemodialysis patients [PDF]

open access: bronze, 2003
Patrick Saudan   +7 more
openalex   +1 more source

Breast and Nipple Dermatoses During Lactation

open access: yesAustralasian Journal of Dermatology, EarlyView.
ABSTRACT Lactation and breastfeeding can present both psychological and physical challenges for breastfeeding mothers. In addition, many nursing mothers will also suffer from breast and nipple dermatoses during this period, compounding these difficulties. Common causes of breast and nipple dermatitis during lactation include eczema, psoriasis, mastitis,
Hamish Moore, Annabel Stevenson
wiley   +1 more source

Novel pathways of heart failure with preserved ejection fraction [PDF]

open access: yes, 2016
INTRODUCTION: Diastolic heart failure (HF) i.e., HF with preserved ejection fraction (HFpEF) accounts for ~50% of all clinical HF presentations; but unlike systolic HF i.e., HF with reduced ejection fraction (HFrEF), there are no evidenced based ...
Li, Shanpeng
core   +1 more source

Coronavirus-19: Possible Therapeutic Implications of Spironolactone and Dry Extract of Glycyrrhiza glabra L. (Licorice) [PDF]

open access: gold, 2020
Decio Armanini   +4 more
openalex   +1 more source

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