Results 131 to 140 of about 45,678 (244)

Implementation of an Integrated Pharmacology Curriculum in a Flipped, Small‐Group, Case‐Based, Pre‐Clerkship Medical Curriculum Improved Student Performance

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Rush Medical College implemented a new, integrated pre‐clerkship curriculum. Pharmacology was integrated with other basic sciences into a flipped, small‐group, case‐based structure. This report describes the main features of the pharmacology curriculum for pharmacology directors to have a template.
Brinda Desai Bradaric, Eric Van Rite, Lalita Prasad‐Reddy, Michael Bradaric   +3 more
wiley   +1 more source

Cardiovascular Health in Women—Across the Lifespan

Clinical Endocrinology, Volume 104, Issue 6, Page 539-555, June 2026.
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar, Jessica Yao, Simone Gong, Madhuka Wijayarathne, Monique Watts, Swati Mukherjee   +5 more
wiley   +1 more source

Dopamine‐Induced Seizure in a Heart Failure Patient: A Case Report and Review of Neurotoxic Implications

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT In heart failure patients, dopamine therapy, particularly at higher doses, may induce seizures due to its impact on cerebral blood flow and exacerbation of underlying hypoxemia and electrolyte imbalances. Close monitoring and cautious use of dopamine, with consideration of alternative inotropic agents like dobutamine, are essential to mitigate
Chuanwei Zhao, Yane Yang, Mu Lin, Zeyao Hu, Linhuan Huang   +4 more
wiley   +1 more source

Crystals as Rockets: Modulation of the Salient Temperature in Cocrystals by Solvent Mixture Composition

Angewandte Chemie, Volume 138, Issue 18, 27 April 2026.
Compositionally engineered mixed solvated cocrystals enable modulation of thermosalient actuation. Guest ratio controls thermosalient temperature and propulsion intensity, providing a tunable platform for designing crystalline systems that exhibit stimuli‐responsive mechanical motion.
Ernesto A. Hernández‐Morales, Dayra Barreto‐Hernández, Dazaet Galicia‐Badillo, Rubén A. Toscano, M. Elena García‐Aguilera, Braulio Rodríguez‐Molina   +5 more
wiley   +2 more sources

Carrier screening in the reproductive setting—Are there medical implications for the heterozygote?—A guide for clinicians

Pregnancy, Volume 2, Issue 3, May 2026.
Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld, Nicole Kasatkin, Bi Liu Yu, Milen Velinov, Justin S. Brandt, Elena Ashkinadze   +5 more
wiley   +1 more source

Spotlight on Spironolactone Oral Suspension for the Treatment of Heart Failure: Focus on Patient Selection and Perspectives

Vascular Health and Risk Management, 2019
Antonis A Manolis,1 Theodora A Manolis,2 Helen Melita,3 Antonis S Manolis4 1Patras University School of Medicine, Patras, Greece; 2Red Cross Hospital, Athens, Greece; 3Onassis Cardiac Surgery Center, Athens, Greece; 4Athens University School of Medicine,
Manolis AA, Manolis TA, Melita H, Manolis AS   +3 more
doaj  

Drainage of Pleural Effusion in the Intensive Care Unit (DOPE‐ICU) Feasibility Trial—Protocol and Statistical Analysis Plan

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 5, May 2026.
ABSTRACT Pleural effusions are common in adult intensive care unit (ICU) patients with respiratory failure. Ultrasonography‐guided therapeutic pleural drainage is widely used and associated with improved oxygenation and ventilatory parameters, but no randomised clinical trial data exist.
Marie Schjødt Worm, Morten Hylander Møller, Niels Henrik Bruun, Anne Craveiro Brøchner, Morten Heiberg Bestle, Bodil Steen Rasmussen, Olav Lilleholt Schjørring   +6 more
wiley   +1 more source

Anti‐inflammatory effects of physical stimuli: The central role of networks in shaping the future of pharmacological research

British Journal of Pharmacology, Volume 183, Issue 10, Page 2177-2196, May 2026.
Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi, Reyhaneh Hooshmandabbasi, Alessandro Ravoni, Ying Ma, Luigi Manni, Timothy J. Koh, Caroline Maake, Tiziana Guarnieri, Darong Lai, Vitalii Zablotskii, Christine Nardini   +10 more
wiley   +1 more source

Low‐Dose vs. Standard Care Iv Human Albumin During Large‐Volume Paracentesis in Patients With Liver Cirrhosis: A Systematic Review

Liver International, Volume 46, Issue 5, May 2026.
ABSTRACT Cirrhosis is a global health concern, with ascites being the most prevalent decompensating event. Intravenous (IV) human albumin (HA) is administered during large‐volume paracentesis (LVP) to prevent complications. The standard (6–8 g HA/L ascites) is empirically chosen, potentially leading to overtreatment and added costs.
Kimberly K. I. M. Bot, Roebi Heus, Joost P. H. Drenth, Marten A. Lantinga   +3 more
wiley   +1 more source

Improving the dissolution properties of spironolactone using liquisolid technique

Pharmaceutical and Biomedical Research, 2015
In this study the effect of liquisolid technique on the dissolution profile of spironolactone was evaluated. Different formulations of spironolactone liquisolid compacts were prepared using various amounts of non-volatile vehicles (Poly ethylene glycol ...
Jafar Akbari, Majid Saeedi, Katayoun Morteza-Semnani, Zaynab Sadeghi Ghadi, Seyed Saeed Hosseini   +4 more
doaj