Results 121 to 130 of about 45,678 (244)

Prescribing Patterns in Pediatric Hidradenitis Suppurativa

Pediatric Dermatology, EarlyView.
ABSTRACT Hidradenitis suppurativa (HS) is an inflammatory skin condition increasingly diagnosed in pediatric populations; however, data on treatment practices in this group remains limited. In this retrospective study of 163 patients diagnosed with HS ≤ 18 years of age, we found that treatment patterns varied significantly by disease severity.
Hannah Neimy, Courtney L. Walker, Lara Wine Lee, Colleen H. Cotton   +3 more
wiley   +1 more source

Efficacy of low dose spironolactone in chronic kidney disease with resistant hypertension

Saudi Journal of Kidney Diseases and Transplantation, 2011
To determine the antihypertensive benefit of adding low dose sprinolactone to multi-drug regimens that included a diuretic, a calcium channel blocker and angiotensin-converting enzyme inhibitor or angiotensin receptor blocker in patients with moderately ...
Rozita Abolghasmi, Omolbanin Taziki
doaj  

Racial Differences in Dermatologic Treatment for Adolescents With PCOS‐Related Acne Vulgaris

Pediatric Dermatology, EarlyView.
ABSTRACT Background/Objectives Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women, with acne frequently appearing during adolescence. Racial and ethnic disparities in PCOS phenotype and adult acne treatment are well documented, yet differences in acne management among adolescents with PCOS remain unclear.
Samantha Garcia, Brandi Kenner‐Bell
wiley   +1 more source

Treatment Patterns in Pediatric Hidradenitis Suppurativa: Time to Treatment Initiation, Initial Treatment, and Time to Switching

Pediatric Dermatology, EarlyView.
ABSTRACT Background Hidradenitis suppurativa (HS) causes significant morbidity in children. Treatment patterns across sex, race, and ethnicity in pediatric HS have not been thoroughly evaluated. We aim to characterize treatment patterns in pediatric HS, including (1) time to treatment initiation, (2) first prescribed HS treatment, and (3) time to ...
Shaliz Aflatooni, Andrea Ure, Kimberly Smart, Julian A. Cortes, Gabriela Palma, Nicole Johnsen, Yvonne Nong, April W. Armstrong   +7 more
wiley   +1 more source

Mineralocorticoid receptor antagonism in acutely decompensated chronic heart failure [PDF]

, 2013
Spironolactone was likely to provide faster congestion relief. -------------------------------------------------------------------------------- Abstract Background/objectives Mineralocorticoid receptor antagonist (MRA) use in acutely ...
Almeida, S., Bettencourt, P., Cyrne-Carvalho, H., Ferreira, J.P., Marques, I., Santos, M.   +5 more
core   +3 more sources

RAD51 and RAD51 paralog inhibition sensitizes nonreplicating quiescent keratinocytes to UV radiation

Photochemistry and Photobiology, EarlyView.
UV radiation and other compounds generate DNA adducts that block transcription and induce cell death if not removed by the nucleotide excision repair system. In this work, we used a small‐scale pharmacological screen to discover that inhibition of the recombinase RAD51 sensitized nonreplicating quiescent keratinocytes to both UVR and other agents that ...
Saman Khan, Angitha Nair, M. Alexandra Carpenter, Michael G. Kemp   +3 more
wiley   +1 more source

Effect of Diuretics on Cutaneous Squamous Cell Carcinoma: Clinical and Translational Evidence

International Journal of Dermatology, EarlyView.
Kevin Sheng‐Kai Ma, Stefano Sol, Fabiana Boncimino, Serena Yun‐Chen Tsai, Bethany J. Brumbaugh, Anna Mandinova, Steven T. Chen   +6 more
wiley   +1 more source

Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes

The Journal of Physiology, EarlyView.
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière, Thomas Boulin, Maëlle Jospin, Alexandre Janin, Gilles Millat, Philippe Chevalier, Olga Andrini   +6 more
wiley   +1 more source

The Aldosterone Blockade for Health Improvement Evaluation in End-Stage Renal Disease (ACHIEVE) Trial: Rationale and Clinical Research Protocol

Canadian Journal of Kidney Health and Disease
Background: The mineralocorticoid aldosterone may contribute to the risk of cardiovascular morbidity and mortality in patients receiving maintenance dialysis. Whether spironolactone, a mineralocorticoid receptor antagonist, improves outcomes for patients
Michael Walsh, David Collister, Martin Gallagher, Patrick B. Mark, Janak R. de Zoysa, Jessica Tyrwhitt, Karthik Tennankore, Laura Sola, Gilmar Reis, Denis Xavier, Russell Villanueva, Wen J. Liu, Camilo Félix, Li Zuo, Mustafa Arici, Vivekanand Jha, Ron Wald, Amanda Y. Wang, Atiya R. Faruqui, Fei Yuan, Shun Fu Lee, Alena Kuptsova, Courtney Christou, P. J. Devereaux,   +24 more
doaj   +1 more source

Renal sodium handling and neurohumoral systems in patients with cirrhosis in sitting posture [PDF]

, 1993
Gerbes, Alexander L., Jüngst, Dieter, Pilz, A., Wernze, Heinrich   +3 more
core   +1 more source