Results 121 to 130 of about 34,497 (254)
Efficacy of low dose spironolactone in chronic kidney disease with resistant hypertension
Saudi Journal of Kidney Diseases and Transplantation, 2011 To determine the antihypertensive benefit of adding low dose sprinolactone to multi-drug regimens that included a diuretic, a calcium channel blocker and angiotensin-converting enzyme inhibitor or angiotensin receptor blocker in patients with moderately ...
Rozita Abolghasmi, Omolbanin Taziki
doaj
Journal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.ABSTRACT Aminoacyl‐tRNA synthetases (ARSs) facilitate the loading of transfer RNAs with their cognate amino acids in the cytosol (ARS1), mitochondria (ARS2), or both (dual ARS). ARS deficiencies are clinically heterogeneous and can cause severe, occasionally fatal disease.
I. J. J. Muffels +21 more
wiley +1 more source
Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.In dogs with MMVD, severe valvular degeneration with chordae tendineae rupture is generally associated with a poor prognosis despite medical management. These three cases demonstrate spontaneous reduction in mitral regurgitation accompanied by decreased coaptation gap, reduced regurgitant volume, reverse cardiac remodelling, discontinuation of ...
Hyo‐Seung Nam, Yein Oh
wiley +1 more source
Effects of Spironolactone on Proteinuria of Patients with Type 2 Diabetes
مجله دانشکده پزشکی اصفهان, 2012 Background: Diabetic nephropathy is the most common cause of kidney failure. We investigated the beneficial effects of spironolactone, alone and in combination with hydrochlorothiazide, on diabetic nephropathy.
Mohamad Karami Horestani +3 more
doaj
Spironolactone Induced Gynecomastia
, 1977 Drug induced gynecomastia has infrequently been reported in the medical literature, but is probably more common than is suspected. A case report illustrating spironolactone induced gynecomastia is presented and various aspects of the condition are ...
Cal Greenlaw
core +1 more source
Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.Abstract A 15‐year‐2‐month‐old, male, neutered domestic shorthair cat was presented for a 1‐week history of increased respiratory effort and declining appetite. Point‐of‐care ultrasound diagnosed tri‐cavitary effusion, and echocardiography revealed the presence of multiple free‐floating hyperechoic nodules within the pericardium.
Maximiliane Gabriele Sehn +4 more
wiley +1 more source
Formulation and research of the solid disper systems of spironolactone [PDF]
, 2012 Introduction: Starting from the fact that spironolactone is practically insoluble in water, its formulation orodispersible is important to enhance dissolution rapid absorption from the oral cavity.
Allaa M. Fathi, Baroud
core
A Spironolactone−Saccharin 1:1 Cocrystal Hemihydrate
, 2016 We investigated the structures of the hydrated and dehydrated states and the in vitro dissolution of a spironolactone−saccharin 1:1 cocrystal hemihydrate, the cocrystal hydrate of a nonionizable, poorly water-soluble drug with a pharmaceutically ...
Hidehiro Uekusa (1441441) +4 more
core +1 more source
Investigating Potential Adverse Drug Reactions of Lisdexamfetamine Using Sequence Symmetry Analysis
Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 5, November 2026.ABSTRACT The prevalence of ADHD is increasing rapidly, and lisdexamfetamine is increasingly popular, but few studies investigate its safety. We performed a sequence symmetry analysis (SSA) using Danish register data to identify potential ADRs associated with lisdexamfetamine in 2013–2023.
Thomas Leth Jensen +8 more
wiley +1 more source
A comparison of the aldosterone-blocking agents eplerenone and spironolactone
, 2008 Improved understand in g of the adverse pharmacological properties of aldosterone has prompted investigation of the clinical benefits of blocking aldosterone at the receptor level.
Krum, Henry +2 more
core +1 more source