Results 111 to 120 of about 45,678 (244)

Preventive Effect of Mineralocorticoid Receptor Antagonists Against Proteinuria Induced by Atezolizumab Plus Bevacizumab Therapy in Hepatocellular Carcinoma: A Multicenter Retrospective Study

Hepatology Research, EarlyView.
Mineralocorticoid receptor antagonists are known to reduce proteinuria in chronic kidney disease, but their effectiveness in preventing bevacizumab‐related proteinuria has not been well established. In the present multi‐institutional retrospective study, we found that these agents significantly delay the onset of moderate or higher grade proteinuria ...
Tomoki Hori, Kazuhiro Yamamoto, Hiroshi Aoi, Yusuke Koizumi, Makoto Kuromatsu, Aiko Fukui, Hiroyo Okamoto, Atsushi Hirata, Kentaro Shinmori, Yuki Imanaka, Miyu Namba, Keisuke Nakanishi, Syunsuke Kitamura, Hideo Tsushima, Ikuko Yano, Kei Moriya, Masaru Matsui, Shigeki Ikushima   +17 more
wiley   +1 more source

Efficacy of spironolactone in treating hidradenitis suppurativa in women of childbearing age: a single-center retrospective analysis

International Journal of Women's Dermatology
Background:. Hidradenitis suppurativa (HS) is a chronic skin disease characterized by recurrent nodules that affect areas with a high density of apocrine sweat glands, such as the axillae and groin.
Suma V. Gangidi, BS, Rachel K. Greene, MD, Eric Olsen, MD, Shanelle Jackson, BS, Mio Nakamura, MD   +4 more
doaj   +1 more source

How safe are herbal products? [PDF]

, 2000
In the search for cures for his ailments, man discovered many healing and toxic properties of plants. Some were found to cure certain diseases while others were found to exert dramatic effects on the body.
Forte, John Stephen
core  

Efficacy and Safety of Dronedarone in Overweight and Obesity: Post Hoc Analysis of the ATHENA Trial

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Introduction Obesity represents a prevalent condition with multiple comorbidities, including atrial fibrillation (AF). Dronedarone, an antiarrhythmic drug (AAD), has demonstrated efficacy in patients with paroxysmal/persistent AF and cardiovascular (CV) risk factors.
Mate Vamos, Anna Vagvolgyi, David S. McKindley, Stefan H. Hohnloser   +3 more
wiley   +1 more source

Update of the EuroGuiDerm evidence‐based guideline for the treatment of acne—Short version

Journal of the European Academy of Dermatology and Venereology, EarlyView.
The 2025 EuroGuiDerm guideline update provides evidence‐based recommendations for acne management, addressing systemic antibiotics, systemic isotretinoin, hormonal therapies including spironolactone and contraceptives, and new topical agents. Key considerations include treatment duration, safety, pregnancy‐specific guidance and minimizing antibiotic ...
Alexander Nast, Bassel H. Al Wattar, Marie Beylot Barry, Holger Brüggemann, Zrinka Bukvić Mokos, Dawn M. Caruana, Klaus Degitz, Clio Dessinioti, Brigitte Dréno, Rieke J. B. Driessen, Harald Gollnick, Merete Hædersdal, Alexander Katoulis, Severin Läuchli, Julien Lambert, Alison M. Layton, Giuseppe Micali, Falk R. Ochsendorf, Thozhukat Sathyapalan, Katarina Zak Stangeland, Simon Francis Thomsen, Daniel Töröcsik, Antonia Pennitz   +22 more
wiley   +1 more source

Clinical, Radiographic, and Histopathologic Features of Human Perigraftitis

Journal of Esthetic and Restorative Dentistry, EarlyView.
ABSTRACT Objective Perigraftitis is a biologic complication associated with dental implants placed in grafted bone, distinct from peri‐implant mucositis and peri‐implantitis. This report further characterizes its clinical, radiographic, and histopathologic features.
Jonathan H. Do, Charles M. Cobb, John T. Shen   +2 more
wiley   +1 more source

Novel pathways of heart failure with preserved ejection fraction [PDF]

, 2016
INTRODUCTION: Diastolic heart failure (HF) i.e., HF with preserved ejection fraction (HFpEF) accounts for ~50% of all clinical HF presentations; but unlike systolic HF i.e., HF with reduced ejection fraction (HFrEF), there are no evidenced based ...
Li, Shanpeng
core   +1 more source

The Determinants of Negotiated Pharmaceutical Prices

The Journal of Industrial Economics, EarlyView.
ABSTRACT We focus on the determinants of pharmaceutical drug prices. Using data from the Brazilian pharmaceutical market, we find large variations in drug prices across buyers, drug classes, and time periods. Our estimation results provide evidence that transaction‐specific determinants between buyers and sellers (e.g., transaction volume, buyer's ...
Ralph B. Siebert, Sebastian Linde, Brandon Norton   +2 more
wiley   +1 more source

Population Pharmacokinetics of Sildenafil in Dogs With Naturally Occurring Pulmonary Hypertension

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The pharmacokinetics of sildenafil are ill‐defined in dogs with naturally occurring pulmonary hypertension (PH). Because the plasma concentrations of sildenafil have not been reported for dogs with this disease, this study aimed to describe the population pharmacokinetics of sildenafil in a sample of dogs with PH. Twenty client‐owned dogs with
Mariko Yata, Teresa C. DeFrancesco, John D. Bonagura, Mark G. Papich   +3 more
wiley   +1 more source

Efficacy and Safety of Low‐Dose Spironolactone in Management of Diabetic Kidney Disease in a Real‐World Setting

Endocrinology, Diabetes & Metabolism
Background Adding spironolactone to renin‐angiotensin‐aldosterone system (RAAS) blockers has been shown to reduce albuminuria in patients with diabetic kidney disease (DKD). However, the increased risk of hyperkalaemia is a major concern.
Manochehr Amini, Davood Dalil, Fatemeh Yaghoubi, Zoleykha Valizadeh, Farnaz Tavakoli, Zohreh Koohpayezadeh   +5 more
doaj   +1 more source