Results 101 to 110 of about 34,497 (254)

Serum Estradiol Concentrations With Estradiol 0.06% Gel in Transgender and Gender‐Diverse Adults

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective Transgender and gender‐diverse individuals undergoing estradiol therapy for gender affirmation are typically treated with oral or transdermal estradiol, with transdermal estradiol recommended for those aged > 45 years. There are limited data evaluating estradiol gel in gender‐affirming hormone therapy regimens. We aimed to assess the
Raquel A. Maggacis   +2 more
wiley   +1 more source

Development of quantitative determination method for spironolactone in compounded syrups.

open access: yes, 2017
Spironolactone is a potassium-sparing diuretic used in congestive heart failure, oedema, hepatic cirrhosis, nephrotic syndrome, hypokalaemia and management of hypertension.
Alfred-Ugbenbo, D., Zdoryk, O. A.
core  

Current Approaches to Support Patients to Withdraw From Image and Performance Enhancing Drugs

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Image and performance‐enhancing drugs (IPEDs) include agents such as androgens, growth hormone, and erythropoietin, which are used to enhance appearance and physical performance. Androgens, also known as anabolic‐androgenic steroids (AAS), are the most used IPEDs worldwide.
Elizabeth Hyams   +3 more
wiley   +1 more source

Astrocytic connexin43 phosphorylation contributes to seizure susceptibility after mild traumatic brain injury

open access: yesThe FEBS Journal, EarlyView.
Astrocytic gap junctions formed by connexin43 (Cx43) help maintain brain homeostasis. After mild traumatic brain injury (TBI), total cortical Cx43 increases and redistributes toward a soluble, non‐junctional pool with elevated hemichannel activity and increased phosphorylation at serine 368 (pCx43S368).
Carmen Muñoz‐Ballester   +11 more
wiley   +1 more source

Spironolactone increases permeability of visceral sheep peritoneum

open access: yes, 2009
Aldosterone is a key component of the renin-angiotensin-aldosterone system, and spironolactone, an aldosterone receptor blocker, shows beneficial effects in patients with end-stage renal disease and heart failure.
Karioti, A.   +10 more
core  

Logistic regression analyses for the use of spironolactone.

open access: yes
Logistic regression analyses for the use of spironolactone.
Bo Yeon Kim (164272)   +4 more
core   +1 more source

Cardiovascular preventive role of thiazolidinedione in patients with type 2 diabetes mellitus undergoing percutaneous coronary intervention

open access: yesJournal of Diabetes Investigation, EarlyView.
Among patients with type 2 diabetes undergoing percutaneous coronary intervention, thiazolidinedione use was independently associated with a significantly reduced risk of a composite of myocardial infarction, stroke, and all‐cause death, notably without an increased risk of admission for heart failure. ABSTRACT Background Thiazolidinediones (TZD) are a
Jinkwon Kim   +5 more
wiley   +1 more source

Efficacy of spironolactone in treating hidradenitis suppurativa in women of childbearing age: a single-center retrospective analysis

open access: yesInternational Journal of Women's Dermatology
Background:. Hidradenitis suppurativa (HS) is a chronic skin disease characterized by recurrent nodules that affect areas with a high density of apocrine sweat glands, such as the axillae and groin.
Suma V. Gangidi, BS   +4 more
doaj   +1 more source

Modulation of sebocyte function in acne: A pathway‐inclusive review

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Acne is multifactorial, with the sebocyte acting as a central immunometabolic hub linking lipogenic, inflammatory, hormonal and barrier pathways. Mapping established and investigational therapies onto this sebocyte‐centred model offers a mechanism‐based framework that complements existing treatment paradigms and may guide more targeted, antibiotic ...
Christos C. Zouboulis   +3 more
wiley   +1 more source

The effect of spironolactone on cardiovascular disease in early stage chronic kidney disease [PDF]

open access: yes, 2011
This thesis examined whether patients with early stage chronic kidney disease (CKD) have abnormalities of arterial stiffness and cardiac function. Aldosterone is known to promote inflammation and fibrosis in the arteries, heart and kidney. Treatment with
Edwards, Nicola Catherine
core   +2 more sources

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