Results 91 to 100 of about 45,678 (244)
Rationale and design of the GUIDE-IT study: Guiding Evidence Based Therapy Using Biomarker Intensified Treatment in Heart Failure. [PDF]
, 2014 OBJECTIVES: The GUIDE-IT (Guiding Evidence Based Therapy Using Biomarker Intensified Treatment in Heart Failure) study is designed to determine the safety, efficacy, and cost-effectiveness of a strategy of adjusting therapy with the goal of achieving and
Adams, Kirkwood F. +15 more
core +3 more sources
Muscle Strength and Power Changes With Gender‐Affirming Hormone Therapy
Andrology, EarlyView.ABSTRACT Background Androgen receptors are highly expressed in upper body muscles, but changes in maximal muscle strength and power in major upper body muscles have not been investigated during gender‐affirming hormone therapy (GAHT). Objective To assess prospective changes in maximal muscle strength and muscle power from before and after 1 year of ...
Mathilde Kamp Nørlund +12 more
wiley +1 more source
Acta Ophthalmologica, EarlyView.Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen +3 more
wiley +1 more source
Cellular Physiology and Biochemistry, 2015 Background: Fibrosis results in excessive buildup of extracellular matrix proteins along with abnormalities in structure and is partly derived by a process involving transforming growth factor β (TGF-β) called endothelial-to-mesenchymal transition (EndMT)
Xiao Chen +8 more
doaj +1 more source
The effect of cardiac resynchronization on morbidity and mortality in heart failure [PDF]
, 2005 Background: Cardiac resynchronization reduces symptoms and improves left ventricular function in many patients with heart failure due to left ventricular systolic dysfunction and cardiac dyssynchrony.
Cleland, John G.F. +6 more
core +1 more source
Alimentary Pharmacology &Therapeutics, EarlyView.We conducted a nationwide, multicenter cohort study using a target trial emulation framework to compare baclofen and acamprosate in patients with compensated alcohol‐associated cirrhosis. After matching, baclofen initiation was associated with a higher 1‐year risk of major adverse liver outcomes, driven primarily by hepatic encephalopathy, particularly
Yee Hui Yeo +13 more
wiley +1 more source
Spironolactone in cardiovascular disease: an expanding universe? [version 1; referees: 2 approved]
F1000Research, 2017 Spironolactone has been marketed for over half a century as a ‘potassium-sparing diuretic’, used primarily in patients with ascites. With the realization that primary aldosteronism is the most common (5-13%) form of secondary hypertension, it has become ...
John W. Funder
doaj +1 more source
Iridoid glucosides from Pentas lanceolata (Forssk.) Deflers growing on the Island of Sardinia [PDF]
, 2014 The ethanolic extract of Pentas lanceolata (Forssk.) Deflers was investigated from a phytochemical point of view and in particular on the monoterpenoid glucosides content.
Bianco, Armandodoriano +3 more
core +1 more source
Alimentary Pharmacology &Therapeutics, EarlyView.In a retrospective cohort of 1,624 adults with cirrhosis, sarcopenia was independently associated with unplanned hospitalization, death, and cirrhosis progression (or death) in patients with decompensated disease. In compensated cirrhosis, sarcopenia was associated only with a higher risk of unplanned hospitalization.
Puneeta Tandon +12 more
wiley +1 more source
Resistant hypertension? Time to consider this fourth-line drug [PDF]
, 2016 Resistant hypertension? Time to consider this fourth-line drug For most adults with resistant hypertension, spironolactone is superior to doxazosin and bisoprolol as an adjunct to triple therapy.
Kaysin, Alexander, Mounsey, Anne
core +2 more sources