Results 91 to 100 of about 34,497 (254)

Tolerability of spironolactone in patients with chronic heart failure:a cautionary message

, 2004
Aim To assess how well heart failure patients tolerate spironolactone in routine clinical practice. Design Retrospective analysis of 226 patients attending a specialist heart failure clinic.
Witham, Miles D., Struthers, Allan D., Gillespie, Neil D.   +2 more
core   +1 more source

Feminizing Therapy in People With Klinefelter Syndrome and Gender Incongruence: Considerations for Treatment Without Testosterone Blockers

Andrology, EarlyView.
ABSTRACT Background Klinefelter syndrome (KS; 47, XXY) usually involves male sex development and gender identity. Small studies suggest gender incongruence may be more common in KS, but feminizing gender‑affirming hormone therapy in this group has been scarcely reported.
Maaike Kroon, Tamira Klaziene Klooker, Sabine Elisabeth Hannema, Martin Den Heijer   +3 more
wiley   +1 more source

COMPARATIV EEFFECTS OF SPIRONOLACTONE AND COMBINATION WITH FUROSEMIDE OF ASCITES FLUID AND BLOOD ELECTROLYTE IN CIRRHOSIS [PDF]

, 2015
Objective: This study was to compare the effects of spironolactone and combination with furosemide on blood electrolyte levels and ascites fluid in patients with cirrhosis.
Muslim, Zamharira, Arifin, Helmi, Zubir, Nasrul   +2 more
core   +1 more source

Spironolactone and Outcomes in Older Patients with Heart Failure and Reduced Ejection Fraction [PDF]

, 2019
BackgroundThe efficacy of mineralocorticoid receptor antagonists or aldosterone antagonists in heart failure with reduced ejection fraction (HFrEF) is well known.
Sheriff, Helen M, Fonarow, Gregg C, Mohammed, Selma F, Lam, Phillip H., Faselis, Charles, Lam, Phillip H, Mohammed, Selma F., Dooley, Daniel J., Morgan, Charity J, Bayoumi, Essraa, Ahmed, Ali, Palant, Carlos E, Singh, Steven, Fonarow, Gregg C., Patel, Samir, Palant, Carlos E., Sheriff, Helen M., Morgan, Charity J., Pitt, Bertram, Dooley, Daniel J   +19 more
core   +1 more source

Prospective Short‐ and Long‐Term Changes in Cardiometabolic Risk Markers Following Gender‐Affirming Hormone Therapy

Andrology, EarlyView.
ABSTRACT Introduction Gender‐affirming hormone therapy (GAHT) may be associated with increased cardiometabolic disease (CMD) risk. Prospective CMD risk screening is recommended, but long‐term data are needed regarding changes in CMD markers. Objectives To evaluate prospective changes in CMD risk markers during GAHT.
Louise Lehmann Christensen, Camilla Viola Palm, Marianne S. Andersen, Guy T'Sjoen, Jan Frystyk, Tine Taulbjerg Kristensen, Rikke Hjortebjerg, Dorte Glintborg   +7 more
wiley   +1 more source

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

Andrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli, Salomé Gallissian, Roxanne Barèges, Félicia Fournier, Catherine Metzler‐Guillemain, Ségolène Prades, Fanny Magnan‐Sebag, Jeanne Perrin   +7 more
wiley   +1 more source

Heart failure medication to prevent cancer therapy–related cardiac dysfunction: A narrative review

British Journal of Pharmacology, EarlyView.
Advances in oncological therapies have improved cancer survival but also have increased the clinical incidence of cancer therapy–related cardiac dysfunction (CTRCD), a spectrum of conditions ranging from subclinical biomarker or strain abnormalities to progressive heart failure and cardiogenic shock.
Fabian Voß, Paul Goerke, Malte Kelm, Amin Polzin   +3 more
wiley   +1 more source

Anti-inflammatory activity of furosemide and spironolactone [PDF]

, 1986
Two diuretics - furosemide and spironolactone - were investigated for anti-inflammatory activity in two models of inflammation, namely, exudative phase (carrageenin-induced rat hind paw oedema) and proliferative phase (cotton pellet-induced granuloma in ...
Vaidya, JS, Diniz, RS, Jain, A
core   +1 more source

Possible drug reaction with eosinophilia and systemic symptoms after spironolactone therapy for clinical hyperandrogenism: a case report

F&S Reports
Objective: To present a case of possible drug reaction with eosinophilia and systemic symptoms (DRESS) after spironolactone and to review existing literature on serious cutaneous adverse reactions to spironolactone.
Sandy Hoang, M.D., Danielle Strom, M.D., Kathleen M. Brennan, M.D.   +2 more
doaj   +1 more source

Metabolic remodelling in anthracycline cardiotoxicity: mechanisms and therapeutic insights

British Journal of Pharmacology, EarlyView.
Cardiac metabolic remodelling in anthracycline‐induced cardiomyopathy and metabolically oriented cardioprotective strategies. Schematic representation of substrate utilization, mitochondrial bioenergetic function and metabolic flexibility in the healthy heart, in anthracycline‐induced cardiomyopathy and under potential cardioprotective interventions ...
Giulia Guerra, Francesco Niro, Marco Mergiotti, Giovanni Gavatorta, Emilio Hirsch, Alessandra Ghigo   +5 more
wiley   +1 more source