Results 141 to 150 of about 33,667 (245)

Belzutifan‐Associated Reversible Heart Failure With Preserved Ejection Fraction in Metastatic Renal Cell Carcinoma

IJU Case Reports, Volume 9, Issue 5, September 2026.
ABSTRACT Background Belzutifan, a hypoxia‐inducible factor 2α (HIF‐2α) inhibitor, is effective for metastatic renal cell carcinoma (mRCC), although its cardiovascular safety profile remains unclear. Case Presentation A 52‐year‐old woman with mRCC developed progressive dyspnea and a 6.7‐kg weight gain 27 days after initiating belzutifan as third‐line ...
Hikaru Kimura, Shigeaki Nakazawa, Yu Ishizuya, Yoshiyuki Yamamoto, Kentaro Takezawa, Taigo Kato, Koji Hatano, Yoichi Kakuta, Atsunari Kawashima, Norio Nonomura   +9 more
wiley   +1 more source

Effect of spironolactone on survival in patients undergoing maintenance hemodialysis.

BackgroundPrevious studies have reported inconsistent results regarding the advantages or disadvantages of spironolactone use in patients undergoing hemodialysis (HD).
Seok Hui Kang, Gui Ok Kim, Bo Yeon Kim, Eun Jung Son, Jun Young Do   +4 more
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Spironolactone Induced Gynecomastia

, 1977
Drug induced gynecomastia has infrequently been reported in the medical literature, but is probably more common than is suspected. A case report illustrating spironolactone induced gynecomastia is presented and various aspects of the condition are ...
Cal Greenlaw
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Neurocardiology: Brain–Heart Interactions in the Heart

MedComm, Volume 7, Issue 9, September 2026.
The heart and brain maintain systemic homeostasis through bidirectional communication involving neural, biochemical, and mechanical pathways. Dysregulation of these pathways contributes to a spectrum of conditions involving heart–brain interactions, including Takotsubo syndrome, the epileptic heart, stroke–heart syndrome, heart failure, cardiac ...
Wentao Wang, Hao Jia, Han Han, Jiangping Song   +3 more
wiley   +1 more source

Spotlight on Spironolactone Oral Suspension for the Treatment of Heart Failure: Focus on Patient Selection and Perspectives

Vascular Health and Risk Management, 2019
Antonis A Manolis,1 Theodora A Manolis,2 Helen Melita,3 Antonis S Manolis4 1Patras University School of Medicine, Patras, Greece; 2Red Cross Hospital, Athens, Greece; 3Onassis Cardiac Surgery Center, Athens, Greece; 4Athens University School of Medicine,
Manolis AA, Manolis TA, Melita H, Manolis AS   +3 more
doaj  

Spironolactone Attenuates Experimental Uremic Cardiomyopathy by Antagonizing Marinobufagenin

, 2009
Spironolactone has been noted to attenuate cardiac fibrosis. We have observed that the cardiotonic steroid marinobufagenin plays an important role in the diastolic dysfunction and cardiac fibrosis seen with experimental renal failure.
Gupta, Shalini, Haller, Steven, Gohara, Sabry, Xie, Zijian, Shapiro, Joseph I., M.D., Bagrov, Alexei Y., Fedorova, Olga V., Tian, Jiang, Taleb, Mohamed, Malhorta, Deepak, El-Okdi, Nasser, Elkareh, Jihad, Shidyak, Amjad, Periyasamy, Sankaridrug M., Cooper, Christopher J.   +14 more
core  

Semen Quality in Transgender Individuals Seeking Fertility Preservation

Andrology, Volume 14, Issue 6, Page 1771-1776, September 2026.
ABSTRACT Background Transgender individuals assigned male at birth (AMAB) may choose to preserve their fertility prior to starting gender‐affirming hormone therapy (GAHT). However, limited data exist regarding the baseline reproductive and hormonal characteristics of this population before and after GAHT.
Maurizio De Rocco Ponce, Eden Troka, Massimiliano Raffo, Luis Miguel Malca Caballero, Alberto Ferlin, Andrea Salonia, Eduard Ruiz Castañé, Alberto Scala, Andrea Garolla, the Gender Incongruence Interdisciplinary Group (GIIG), Andrea Garolla, Anna Aprile, Camillo Barbisan, Anna Belloni Fortina, Valentina Camozzi, Elena Campello, Annamaria Cattelan, Chiara Ceolin, Fabrizio Dal Moro, Giorgio De Conti, Angela Favaro, Alberto Ferlin, Francesco Francini Pesenti, Michela Gatta, Marta Ghisi, Sandro Giannini, Laura Guazzarotti, Massimo Iafrate, Paolo Meneguzzo, Marina Miscioscia, Giulia Musso, Giancarlo Ottaviano, Corrado Marchese Ragona, Carlo Saccardi, Lolita Sasset, Rossana Schiavo, Giuseppe Sergi, Paolo Simioni, Benedetta Tascini, Eleonora Vania, Elisa Varotto, Francesca Venturini, Tommaso Vezzaro, Fabrizio Vianello   +43 more
wiley   +1 more source

Systemic medications associate with surgically treated cataract among adults over 50 years in Finland

Acta Ophthalmologica, Volume 104, Issue 6, Page e630-e647, September 2026.
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen, Jari Haukka, Tuomas Lilius, Sirpa Loukovaara   +3 more
wiley   +1 more source

Sodium zirconium cyclosilicate compared with potassium restriction for hyperkalemia management in type 2 diabetes: The SILVERSTAR trial

Journal of Diabetes Investigation, Volume 17, Issue 9, Page 1625-1633, September 2026.
ABSTRACT Aims/Introduction To demonstrate noninferiority of continued sodium zirconium cyclosilicate therapy versus a potassium‐restricted diet in achieving normokalemia at Visit 7 (Days 28–42) in individuals with type 2 diabetes and hyperkalemia, using a noninferiority margin of −10 percentage points (one‐sided α = 0.025).
Masahide Hamaguchi, Junya Hironaka, Hiroshi Okada, Mari Yoneda, Ayaka Kobayashi, Yoshitaka Hashimoto, Aya Kitae, Noriyuki Kitagawa, Akio Kishi, Michiyo Ishii, Mai Asano, Masahiro Yamazaki, Toru Tanaka, Hanako Nakajima, Eiko Sato, Michiaki Fukui   +15 more
wiley   +1 more source

Comparison of Spironolactone versus Amlodipine in Hypertensive Cardiorenal Pathology [PDF]

, 2016
Hypertension is endemic worldwide, afflicting up to 40% of the global population over the age of 25. Haemodynamic stretch stress from raised blood pressure is a driver for organ damage in the heart and kidney, contributing to potentially fatal conditions.
Strickland, James Todd Langdale
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