Results 201 to 210 of about 59,693 (345)
FORMULATION AND CHARACTERIZATION OF SELF EMULSIFYING DRUG DELIVERY SYSTEM OF SPIRONOLACTONE
, 1970 Ankur Gupta +3 more
openalex +2 more sources
Improved bioavailability and clinical response in patients with chronic liver disease following the administration of a spironolactone: β‐cyclodextrin complex [PDF]
, 1997 A. Z. M. Abosehmah‐Albidy +4 more
openalex +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend PANX1 and PANX3 show opposite expression patterns in patient‐derived normal skin and cutaneous squamous cell carcinoma (cSCC) tumours, with PANX1 increased and PANX3 mRNA decreased in cSCC tumours compared to skin. Within the tumour PANX1 localizes to all regions, including tumour nests which house cSCC cancer cells and tumour ...
Brooke L. O'Donnell +11 more
wiley +1 more source
Improving the dissolution properties of spironolactone using liquisolid technique
Pharmaceutical and Biomedical Research, 2015 In this study the effect of liquisolid technique on the dissolution profile of spironolactone was evaluated. Different formulations of spironolactone liquisolid compacts were prepared using various amounts of non-volatile vehicles (Poly ethylene glycol ...
Jafar Akbari +4 more
doaj
Advancing antihypertensive drug development
British Journal of Pharmacology, Volume 182, Issue 15, Page 3389-3410, August 2025.Hypertension affects more than a billion individuals worldwide and remains a major cause of cardiovascular morbidity and mortality. Despite advances in therapies, optimal blood pressure control remains elusive for many patients because of treatment resistance, adverse effects, and adherence challenges.
Fay Pu +5 more
wiley +1 more source
Spironolactone is an Effective and Well Tolerated Systemic Antiandrogen Therapy for Hirsute Women*
, 1989 Julian H. Barth +3 more
openalex +1 more source
Stability of ketoconazole, metolazone, metronidazole, procainamide hydrochloride, and spironolactone in extemporaneously compounded oral liquids [PDF]
, 1996 Loyd V Allen, Martin A. Erickson
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British Journal of Clinical Pharmacology, Volume 91, Issue 7, Page 1937-1946, July 2025.Aims The aim of this phase 1 trial was to assess the pharmacokinetics, safety and tolerability of balcinrenone (previously AZD9977) in participants with severe renal impairment vs. those with normal renal function. Methods Participants with severe renal impairment (estimated glomerular filtration rate [eGFR] < 30 mL/min/1.73 m2) not on dialysis were ...
Chandrali S. Bhattacharya +10 more
wiley +1 more source
Why does spironolactone improve mortality over and above an ACE inhibitor in chronic heart failure? [PDF]
, 1999 Allan D. Struthers
openalex +1 more source