Results 21 to 30 of about 11,991 (261)

Hemodynamic Characterization of Arterialized and Nonarterialized Liver Transplants in the Rat

Canadian Journal of Gastroenterology, 2001
Persistent hyperkinetic circulation after liver transplantation has been described in humans, but similar changes have not been well characterized in the rat model.
John Wong, Yikun Zhang, Samuel S Lee
doaj   +1 more source

Pathogenesis of the hypertriglyceridemia at early stages of alcoholic liver injury in the baboon.

Journal of Lipid Research, 1990
To study the mechanism of alcoholic hypertriglyceridemia, baboons were pair-fed liquid diets containing 50% of energy as ethanol or as additional carbohydrate for 5-16 months.
M J Savolainen, E Baraona, M A Leo, C S Lieber   +3 more
doaj   +1 more source

Anticoagulation in splanchnic and cerebral vein thrombosis: An international vignette‐based survey

Research and Practice in Thrombosis and Haemostasis, 2020
Background Anticoagulant treatment of splanchnic (SVT) and cerebral vein thrombosis (CVT) can be challenging due to the rarity of these conditions, the concomitantly high thrombotic and bleeding risks, and the available low‐quality evidence.
Nicoletta Riva, Marc Carrier, Alex Gatt, Walter Ageno   +3 more
doaj   +1 more source

Central hemodynamic and splanchnic circulation in children with meningococcal septic shock

Regulatory Mechanisms in Biosystems, 2017
Meningococcal infection is caused by the bacterium Neisseria meningitidis (also termed meningococcus). Invasive meningococcal disease remains a rare infectious disease not only with high mortality but also with important morbidity and remains as a ...
M. A. Georgiyants, V. A. Korsunov, O. M. Olkhovska   +2 more
doaj   +1 more source

Splanchnic Venous Compression Enhances the Effects of ß‐Blockade in the Treatment of Postural Tachycardia Syndrome

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Splanchnic venous pooling induced by upright posture triggers a compensatory increase in heart rate (HR), a response that is exaggerated in patients with postural tachycardia syndrome.
Emily C. Smith, André Diedrich, Satish R. Raj, Alfredo Gamboa, Cyndya A. Shibao, Bonnie K. Black, Amanda Peltier, Sachin Y. Paranjape, Italo Biaggioni, Luis E. Okamoto   +9 more
doaj   +1 more source

Activation of AMP-activated Protein Kinase by Metformin Inhibits Dedifferentiation of Platelet-derived Growth Factor-BB-induced Vascular Smooth Muscle Cells to Improve Arterial Remodeling in Cirrhotic Portal HypertensionSummary

Cellular and Molecular Gastroenterology and Hepatology
Background & Aims: Portal hypertension (PHT) is the potentially deadly complication of liver cirrhosis. Intrahepatic vascular resistance and the splanchnic hyperdynamic circulation are 2 principal driving factors contributing to the maintenance and ...
Guangbo Wu, Qiang Fan, Min Chen, Guqing Luo, Zhenghao Wu, Jinbo Zhao, Jiayun Lin, Chihao Zhang, Hongjie Li, Xiaoliang Qi, Haizhong Huo, Lei Zheng, Meng Luo   +12 more
doaj   +1 more source

Management of Cardiopulmonary Complications of Cirrhosis

International Journal of Hepatology, 2011
Advanced portal hypertension accompanying end-stage liver disease results in an altered milieu due to inadequate detoxification of blood from splanchnic circulation by the failing liver.
Prabha Sawant, C. Vashishtha, M. Nasa
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Born Again: Recurrent Hepatic Encephalopathy in an Adult without Cirrhosis

Journal of Gastrointestinal and Abdominal Radiology, 2019
Congenital extrahepatic portosystemic shunt (CEPS) develops between the por-to-mesenteric and systemic veins. The splanchnic venous system drains directly to systemic circulation in this condition.
Tom George, Sasidharan Rajesh, Cyriac Abby Philips   +2 more
doaj   +1 more source