Results 151 to 160 of about 490,454 (267)

Possible Triggering of Molecular Mimicry by Environmental Pollution. [PDF]

Biology (Basel)
Mishina S, Adams B, Uhal B, Liang Y.
europepmc   +1 more source

Optimization of B Cell Responses in Human Immune System Mice Through Organoid Based Screening

Advanced Science, EarlyView.
Human immune system (HIS) mice show limited B cell responses to immunization. Using HIS mouse spleen organoids, this study identifies cytokine combinations and innate immune signals that drive human B cell expansion, differentiation, and class‐switch. Applying these signals in vivo through temporal separation enables antigen‐specific IgG responses and ...
Haiqiao Sun, He Li, Xu Zhu, Zijian Zhang, Deshan Ren, Shuai Ding, Yan Li   +6 more
wiley   +1 more source

Rovadicitinib, a first-in-class JAK/ROCK inhibitor, in patients with myelofibrosis: a preclinical and phase I study. [PDF]

Blood Cancer J
Xu Z, Liu J, Hong Z, Yin Q, Zuo X, Wen Q, Li L, Chang C, Du X, Wang Y, Yang X, Yang C, Jia H, Pan L, Xiao Z.   +14 more
europepmc   +1 more source

Celastrol‐Loaded Conductive Hydrogel Mitigates Myocardial Ischemia‐Reperfusion Injury and Restores Electrophysiological Function

Advanced Science, EarlyView.
Schematic illustration of the Pluronic F127 diacrylate/gelatin methacryloyl/poly(3,4‐ethylenedioxythiophene):poly(styrenesulfonate)/celastrol hydrogel (FGPC) for localized myocardial ischemia–reperfusion injury treatment. FGPC combines sustained celastrol delivery with PEDOT:PSS‐mediated conductive support to attenuate acute oxidative/inflammatory ...
Shixin Wang, Shaojie Chen, Chengzong Li, Hongyi Cheng, Jincheng Jiao, Xiafeng Peng, Yike Zhang, Wei Sun, Feng Zhang, Chang Cui, Minglong Chen   +10 more
wiley   +1 more source

Evaluation of segmentation accuracy and the improvement of time effectiveness using deep learning-based segmentation in ¹⁷⁷Lu-DOTATATE dosimetry. [PDF]

EJNMMI Phys
Nakaichi T, Shimizu Y, Nakamura S, Shuto Y, Kasai Y, Shishido A, Kunito K, Nakayama H, Takemori M, Kawamura M, Chiba T, Okamoto H, Kashihara T, Igaki H, Ito K.   +14 more
europepmc   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Bibliometric analysis of entecavir for the treatment of cirrhosis in hepatitis B

Asian Journal of Surgery
Yu Zhang, Yi Zhou
doaj   +1 more source

Integrated Proteomics and Metabolomics Analysis Reveals Potential Pathways Underlying Onion-Mediated Regulation of Spleen Immune Function in Liangshan Black Sheep. [PDF]

Vet Sci
Huang Z, Wang J, Huang Z, Lv G, Wang H, Yang C, Jiang S, Hao G, Zhang Y.   +8 more
europepmc   +1 more source

A Fentanyl‐Responsive Microneedle Patch for Harm Reduction

Advanced Science, EarlyView.
A fentanyl‐responsive microneedle patch is developed as a self‐regulating overdose intervention that releases naloxone upon detecting fentanyl. The system employs aptamer‐functionalized nanoparticles embedded in a swellable polymer matrix to enable rapid, on‐demand drug delivery through the skin.
Penghui Zhao, Zerui Zhou, Tyler Wolter, Huanqing Niu, Yuanzhi Bian, Chixia Tian, Chun Xu, Chenming Zhang, Juhong Chen, Matthew W. Buczynski, Wujin Sun   +10 more
wiley   +1 more source

Comparative study of Gd-EOB-DTPA-enhanced magnetic resonance imaging signal intensity parameters and albumin-bilirubin grade for liver function assessment based on early and middle-stage of liver dysfunction. [PDF]

Quant Imaging Med Surg
Xia R, Wu X, Zheng J, Wang X, Peng W.
europepmc   +1 more source