Results 61 to 70 of about 757,464 (353)

Laparoscopic or open liver resection for intrahepatic cholangiocarcinoma: A meta-analysis and systematic review

open access: yesFrontiers in Oncology, 2023
BackgroundAlthough laparoscopic hepatectomy has been widely used in the treatment of benign and malignant liver diseases, its applicability in intrahepatic cholangiocarcinoma (ICC) is controversial.
Xin Zhao   +16 more
doaj   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

open access: yesFEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil   +5 more
wiley   +1 more source

Curzerene suppresses hepatocellular carcinoma progression through the PI3K/AKT/MTOR pathway

open access: yesRevista de Investigación Clínica
Background: Hepatocellular carcinoma (HCC) is one of the most aggressive cancers worldwide. Curzerene is a sesquiterpene and component of Curcuma rhizomes and has anti-tumor and anti-inflammatory properties.
Yihui Luo   +4 more
doaj   +1 more source

Traditional Chinese medicine compounds for the treatment of functional dyspepsia: an updated meta-analysis of randomized, double-blind, placebo-controlled trials

open access: yesDigital Chinese Medicine, 2021
Objective: To evaluate the efficacy and safety of traditional Chinese medicine (TCM) compounds for the treatment of functional dyspepsia (FD). Methods: The PubMed, Embase, Cochrane Library, Web of Science, Chinese Biomedical Database (CBM), Wanfang Data,
Luo Xiaoying   +6 more
doaj   +1 more source

Identification of a novel cell type in peripheral lymphoid organs of mice. IV. Identification and distribution in mouse spleen

open access: yesJournal of Experimental Medicine, 1975
White pulp nodules of mouse spleen contain a minor population of cells with morphologic features that are identical to those of dendritic cells, a cell type recently described in vitro.
R. Steinman, J. Adams, Z. Cohn
semanticscholar   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

TBA-MLR score: a metabolic-immune prognostic biomarker for postoperative hepatocellular carcinoma

open access: yesFrontiers in Immunology
ObjectiveTo develop and validate a novel prognostic score combining serum total bile acid (TBA) and monocyte-to-lymphocyte ratio (MLR) for improved risk stratification in hepatocellular carcinoma (HCC) patients after radical hepatectomy.MethodsIn 508 HCC
Yuanquan Zhao   +6 more
doaj   +1 more source

The Method of Combining Internal and External Treatment of Ulcerative Colitis in Chinese Medicine

open access: yesChinese Medicine and Natural Products, 2023
Traditional Chinese medicine (TCM) believes that the main pathogenesis of ulcerative colitis is spleen deficiency; damp heat in the large intestine as the symptom, the treatment must be warming, clearing, eliminating, tonifying, astringing concurrently ...
Qian Dai, Chunyan Dai, Jie Han
doaj   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

open access: yesMolecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li   +12 more
wiley   +1 more source

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