Results 51 to 60 of about 612,842 (306)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Nursing strategies after pancreaticoduodenectomy: continuity of care combined with immunomodulatory nutrition

Frontiers in Surgery
BackgroundPancreaticoduodenectomy (PD) is a highly invasive procedure with a long operation time, resulting in a high incidence of postoperative complications. The quality of patient care remains a key factor in improving prognosis.
Xiaodong Feng, Wei Li, Yufu Tang, Lei Han, Ting Bi, Wei Zhang, Yuqing Miao   +6 more
doaj   +1 more source

Wandering spleen: A common presentation of an uncommon anomaly [PDF]

, 2009
Background: With the advent of real time ultrasonography of the abdomen, the spleen is no longer an inaccessible organ. Wandering spleen is a rare entity with only less than 500 cases reported so far.
Ugwu , AC, Imo, AO, Ugwu, AC, Ogbonna, CO   +3 more
core  

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Curzerene suppresses hepatocellular carcinoma progression through the PI3K/AKT/MTOR pathway

Revista de Investigación Clínica
Background: Hepatocellular carcinoma (HCC) is one of the most aggressive cancers worldwide. Curzerene is a sesquiterpene and component of Curcuma rhizomes and has anti-tumor and anti-inflammatory properties.
Yihui Luo, Zhenchang Wang, Jun’e Jiang, Shanshan Wu, Yang Zhai   +4 more
doaj   +1 more source

Intradermal acupuncture for rheumatoid arthritis: study protocol for a randomised controlled trial

Trials, 2021
Background Rheumatoid arthritis (RA) is a common autoimmune disease that severely impacts quality of life. Currently available medications for the treatment of RA have adverse side effects.
Huifang Luo, Jie Peng, Qing Ma, Zhihua Wei, Changsong Lin, Mingying Zhang, Peiwu Li, Yang Song, Xiangwei Yang   +8 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Clinical analysis on comparison of outcomes between partial splenic artery embolization and splenectomy for management of grade II–III splenic injury in blunt trauma

European Journal of Medical Research
Background The spleen is also the largest lymphoid organ and has important immune and haematopoietic functions. Traumatic splenic rupture often results in haemorrhagic shock and is life-threatening.
Xiaolong Xu, Meng Lv, Cheng Wang, Jianfeng Mei   +3 more
doaj   +1 more source

TBA-MLR score: a metabolic-immune prognostic biomarker for postoperative hepatocellular carcinoma

Frontiers in Immunology
ObjectiveTo develop and validate a novel prognostic score combining serum total bile acid (TBA) and monocyte-to-lymphocyte ratio (MLR) for improved risk stratification in hepatocellular carcinoma (HCC) patients after radical hepatectomy.MethodsIn 508 HCC
Yuanquan Zhao, Wei Huang, Xiwen Deng, Pengyang Li, Siyang Yao, Yongyu Yang, Xiaofeng Dong   +6 more
doaj   +1 more source

Exploring the regenerative capacity of the spleen following irradiation [PDF]

Introduction: Haematopoietic stem cell transplantation (HSCT) is commonly used to treat patients with haematological disorders. Myeloablative conditioning is an important preparation for patients receiving haematopoietic stem cells (HSC) or ...
O'Neill, Helen C, Tan, Jonathan Kah Huat, Short, Christie TM, Tan, Jonathan KH, O’Neill, Helen C, Short, Christie   +5 more
core   +1 more source