Results 31 to 40 of about 808,301 (296)

A Lucky Mistake: The Splenic Glands of Marcello Malpighi [PDF]

, 2017
PURPOSE OF THE REVIEW: More than 50% of all gynaecological cancers can be classified as rare tumours (defined as an annual incidence of
Chaviano, Felicia, Orazi, Attilio, Pizzi, Marco, Rugge, Massimo   +3 more
core   +1 more source

Pogostemon cablin Acts as a Key Regulator of NF-κB Signaling and Has a Potent Therapeutic Effect on Intestinal Mucosal Inflammation

Mediators of Inflammation
Persistent intestinal inflammation is a major contributor to various diseases, including digestive disorders, immune dysregulation, and cancer. The NF-κB signaling pathway is pivotal in the inflammatory response of intestinal cells, regulating the ...
Yuqing Deng, Xin Liang, Long Zhao, Xin Zhou, Jianqin Liu, Zhi Li, Shanshan Chen, Guohui Xiao   +7 more
doaj   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Research Progress on Salvia miltiorrhiza Bioactive Components Regulating P-Selectin for Microcirculatory Improvement: Potential Implications in Acute Pancreatitis

Mediators of Inflammation
Severe acute pancreatitis (SAP) is associated with high morbidity and mortality. Microcirculatory dysfunction is a critical pathological event in this process and a primary contributor to organ failure (OF).
Yali Liu, Xinyi Ao, Weian Hao, Honglian Wang, Li Li, Shuang Wang, Jinyi Li, Jianqin Liu, Xin Zhou, Zhi Li   +9 more
doaj   +1 more source

Functional characterization of reappearing B cells after anti-CD20 treatment of CNS autoimmune disease. [PDF]

, 2018
The anti-CD20 antibody ocrelizumab, approved for treatment of multiple sclerosis, leads to rapid elimination of B cells from the blood. The extent of B cell depletion and kinetics of their recovery in different immune compartments is largely unknown ...
Bernard, Claude CA, Brück, Wolfgang, Feldmann, Linda, Häusler, Darius, Häusser-Kinzel, Silke, Lehmann-Horn, Klaus, Lepennetier, Gildas, Torke, Sebastian, Weber, Martin S, Zamvil, Scott S   +9 more
core   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Epidermoid Cyst of Spleen [PDF]

, 2010
Splenic cysts are very rare lesions, most of them being parasitic systs. Nonparasitic cysts are uncommon. We report a case of young female who presented with mass and pain abdomen. Ultrasound examination revealed splenic syst. The diagnosis of epidermoid
Usha, R, Vijay Shankar, S
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Research progress on animal models of autoimmune gastritis

Autoimmunity
Autoimmune gastritis (AIG) is an autoimmune disease characterized primarily by the destruction of gastric parietal cell structure and atrophy of the gastric fundic and body mucosa. The global prevalence of AIG is approximately 3.85%.
Jiaqi Wang, Xiyan Zhang, Jinna Tao, Baixiang He, Lan Wang, Zhongmian Zhang, Yiyuanzi Zhao, Zhihong Li   +7 more
doaj   +1 more source

Intradermal acupuncture for rheumatoid arthritis: study protocol for a randomised controlled trial

Trials, 2021
Background Rheumatoid arthritis (RA) is a common autoimmune disease that severely impacts quality of life. Currently available medications for the treatment of RA have adverse side effects.
Huifang Luo, Jie Peng, Qing Ma, Zhihua Wei, Changsong Lin, Mingying Zhang, Peiwu Li, Yang Song, Xiangwei Yang   +8 more
doaj   +1 more source