Results 31 to 40 of about 490,454 (267)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Prognostic impact of albumin-bilirubin score in predicting the long-term survival of distal cholangiocarcinoma after radical surgery

World Journal of Surgical Oncology
Background The Albumin-Bilirubin Score (ALBI) serves as an indicator of nutritional status and is a widely recognized prognostic biomarker in cancer patients.
Jin-Can Huang, You-Wei Ma, Han-Xuan Wang, Ren Lang, Tao Jiang   +4 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

The efficacy and safety of thymosin alpha-1 combined with lenvatinib plus sintilimab in unresectable hepatocellular carcinoma: a retrospective study

Scientific Reports
To validate the efficacy and safety of thymosin α-1 combined with lenvatinib plus sintilimab in the treatment of unresectable hepatocellular carcinoma.
Siyang Yao, Qiangsong Huang, Yan Zou, Tianqi Liu, Yongyu Yang, Tao Huang, Yuanquan Zhao, Xiaofeng Dong   +7 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Effect and satisfaction analysis of perioperative nursing in secondary hyperparathyroidism

Journal of the Pakistan Medical Association
Objective: To assess the effect and satisfaction of perioperative nursing in secondary hyperparathyroidism patients. Method: The study was conducted at the General Hospital of Northern Theatre Command, Shenyang, China, from January 2021 to December 2022,
Xiaodong Feng, Ting Bi, Wei Li, Yang Tong,  Yufu Tang, Sijia Bai, Guangming Cheng, Jie Qin, Wei Zhang   +8 more
doaj   +1 more source

Intradermal acupuncture for rheumatoid arthritis: study protocol for a randomised controlled trial

Trials, 2021
Background Rheumatoid arthritis (RA) is a common autoimmune disease that severely impacts quality of life. Currently available medications for the treatment of RA have adverse side effects.
Huifang Luo, Jie Peng, Qing Ma, Zhihua Wei, Changsong Lin, Mingying Zhang, Peiwu Li, Yang Song, Xiangwei Yang   +8 more
doaj   +1 more source

Massage combined with auricular point sticking and pressing therapy for one cases of insomnia and related nursing management (推拿联合耳穴贴压治疗失眠1例护理体会)

中西医结合护理, 2021
This paper summarized the nursing experience of a patient with insomnia who received a massage combined with auricular point sticking and pressing therapy.
WANG Xinyue (王欣悦), MA Xu (马旭), ZHANG Pin (张聘), XU Bing (许冰), TANG Ling (唐玲)   +4 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Effect of Quadruple Regimen with Lansoprazole on Elderly Patients with Chronic Atrophic Gastritis and Its Influence on Gastric Function

Guoji laonian yixue zazhi
Objective To explore the effect of quadruple regimen with Lansoprazole in elderly patients with chronic atrophic gastritis and its influence on gastric function.
Zhang Wanglai, Shao Huang, Tao Yunsheng, Li Meng, Zhou Zelin, Wu Funing   +5 more
doaj   +1 more source