Results 21 to 30 of about 808,301 (296)

Spatial heterogeneity and peptide availability determine CTL killing efficiency in vivo [PDF]

, 2014
The rate at which a cytotoxic T lymphocyte (CTL) can survey for infected cells is a key ingredient of models of vertebrate immune responses to intracellular pathogens. Estimates have been obtained using in vivo cytotoxicity assays in which peptide-pulsed
A Wiedemann, A Yates, AJ Yates, AL DeVico, AM Beal, AM Byers, Andrew Yates, AS Perelson, AS Perelson, AS Perelson, AS Perelson, B Breart, Benedict Seddon, Bjoern Peters, CA Macken, D Zagury, DH Busch, DL Barber, EA Grimm, ER Christinck, F Graw, F Graw, G Chu, LG Guidotti, M Bajénoff, M Poe, MA Purbhoo, MH Foley, MR Jenkins, P Perez, RR Regoes, RR Regoes, S Budhu, S Valitutti, SE Henrickson, SH van der Burg, Sim Tung, Thea Hogan, TR Mempel, Ulrich Kadolsky, VV Ganusov, VV Ganusov, VV Ganusov, VV Ganusov, W Barchet, Y Sykulev, YW Jung   +46 more
core   +4 more sources

MIF-mediated hemodilution promotes pathogenic anemia in experimental African trypanosomosis [PDF]

, 2016
Animal African trypanosomosis is a major threat to the economic development and human health in sub-Saharan Africa. Trypanosoma congolense infections represent the major constraint in livestock production, with anemia as the major pathogenic lethal ...
Beschin, Alain, Bieniasz-Krzywiec, Pawel, Brys, Lea, Bucala, Richard, Caljon, Guy, De Baetselier, Patrick, De Trez, Carl, Korf, Hannelie, Leng, Lin, Magez, Stefan, Mazzone, Massimiliano, Odongo, Steven, Sparkes, Amanda, Stijlemans, Benoît, Van Den Abbeele, Jan, Van Ginderachter, Jo A, Vanbekbergen, Nele, Vansintjan, Liese   +17 more
core   +5 more sources

Targeting of the COX-2/PGE2 axis enhances the antitumor activity of T7 peptide in vitro and in vivo

Drug Delivery, 2021
T7 peptide is considered as an antiangiogenic polypeptide. The presents study aimed to further detect the antiangiogenic mechanisms of T7 peptide and determine whether combining T7 peptide and meloxicam (COX-2/PGE2 specific inhibitor) could offer a ...
Jianrong Yang, Jingtao Zhong, Mi Zhou, Yinghong Zhou, Peng Xiu, Feng Liu, Fuhai Wang, Zelun Li, Yuntian Tang, Yuanyuan Chen, Siyang Yao, Tao Huang, Tianqi Liu, Xiaofeng Dong   +13 more
doaj   +1 more source

Ancient Respected and Modern Absorbed, Chinese Essence and Western Utility—Thoughts of the Integrated Chinese Medicine and Western Medicine

Chinese Medicine and Natural Products, 2022
Traditional Chinese medicine (TCM) and Western medicine are two medical systems formed in different cultural backgrounds. The differences between them are that TCM focuses on the study of the invisible state while Western medicine focuses more on the ...
Xiaofa Liu, Diangui Li, Shengda Lu
doaj   +1 more source

Gestational hypothyroxinemia affects its offspring with a reduced suppressive capacity impairing the outcome of the experimental autoimmune encephalomyelitis [PDF]

, 2018
Indexación: Scopus.Hypothyroxinemia (Hpx) is a thyroid hormone deficiency (THD) condition highly frequent during pregnancy, which although asymptomatic for the mother, it can impair the cognitive function of the offspring.
Albornoz, E., Binzberger, R., Bueno, S.M., Bugueño, K., Cabello-Verrugio, C., Elorza, A.A., Haensgen, H., Jara Fernández, E.L., Kalergis, A.M., Opazo, M.C., Riedel, C.A., Rivero-Castillo, T., Simon, F., Venegas Salas, L.F.   +13 more
core   +2 more sources

The spleen: a hub connecting nervous and immune systems in cardiovascular and metabolic diseases [PDF]

, 2017
Metabolic disorders have been identified as major health problems affecting a large portion of the world population. In addition, obesity and insulin resistance are principal risk factors for the development of cardiovascular diseases.
Carnevale, Daniela, Lembo, Giuseppe, Lori, Andrea, Perrotta, Marialuisa   +3 more
core   +2 more sources

To achieve an earlier IFN-¿ response is not sufficient to control mycobacterium tuberculosis infection in mice [PDF]

, 2014
The temporo-spatial relationship between the three organs (lung, spleen and lymph node) involved during the initial stages of Mycobacterium tuberculosis infection has been poorly studied.
Barril, Carles, Cardona, Pere-Joan, Díaz, Jorge, López, Daniel, Marzo, Elena, Prats, Clara, Universitat Autònoma de Barcelona, Valls, Joaquim, Vegué, Marina, Vilaplana, Cristina   +9 more
core   +9 more sources

Spleen findings in drowning [PDF]

, 1993
A retrospective study of spleen findings in 42 victims of drowning and a comparison group of 42 cases of asphyxiation due to other causes (hanging, ligature strangulation and manual strangulation), that were matched for sex, age, body weight and build ...
Erdelkamp, J., Graw, Matthias, Haffner, H. Th.   +2 more
core   +1 more source

Traditional Chinese medicine based on Tongjiang methodology combined with proton pump inhibitor (PPI) step-down in treating non-erosive reflux disease: a study protocol for a multicentered, randomized controlled clinical trial

Trials, 2022
Background Non-erosive reflux disease (NERD) is characterized by typical gastroesophageal reflux symptoms, such as heartburn and regurgitation but an absence of esophageal mucosal damage during upper gastrointestinal endoscopy.
Xia Li, Haomeng Wu, Beihua Zhang, Ting Chen, Xiaoshuang Shi, Jinxin Ma, Jiaqi Zhang, Xudong Tang, Fengyun Wang   +8 more
doaj   +1 more source

Research progress of Traditional Chinese Medicine characteristic nursing techniques for functional constipation in the elderly (老年功能性便秘中医特色护理研究进展)

中西医结合护理, 2021
The functional constipation is common in the elderly and can result in organic disease if it persists for many years. Based on basic theory of Traditional Chinese Medicine(TCM) and syndrome differentiation, the TCM characteristic nursing techniques are ...
LIU Miao (刘苗), HU Hairong (胡海荣), QI Huan (祁欢), XU Bing (许冰)   +3 more
doaj   +1 more source