Results 261 to 270 of about 434,859 (340)

Metastasis of nasopharyngeal carcinoma to the spleen: a case report. [PDF]

AME Case Rep
Alfirm R, Alrobian A, Alessa M, Hijazi N, Almalki M.   +4 more
europepmc   +1 more source

Spontaneous rupture of malarial spleen presenting as hemoperitoneum: a case report [PDF]

, 2010
Nikhil Gupta, Pawanindra Lal, Anubhav Vindal, Niladhar S. Hadke , Nita Khurana
core  

OCIAD2 Stabilizes Integrin β1 Signaling Through SNX17‐Mediated Endosomal Recycling to Lipid Rafts and Modulates Cisplatin Response in HNSCC

Advanced Science, EarlyView.
This study identifies OCIAD2 as a critical regulator of cisplatin resistance in HNSCC. Mechanistically, OCIAD2 stabilizes integrin β1 through a direct physical interaction and facilitates its SNX17‐dependent endosomal recycling to lipid raft microdomains. Targeting OCIAD2 disrupts integrin β1 trafficking and significantly enhances cisplatin sensitivity,
Li Cui, Shanshan Si, Min Ye, Pei Lin, Meiyan Zou, Yunfan Lin, Xu Chen, Bing Guo, Wenjuan Sun, Xinyuan Zhao   +9 more
wiley   +1 more source

Antimetastatic effects of MRTX1133 KRAS G12D specific inhibitor in a liver metastatic model of pancreatic ductal adenocarcinoma. [PDF]

Sci Rep
Szigeti KA, Baranyi M, Surguta S, Hegedűs B, Piurkó V, Tóvári J, Tímár J.   +6 more
europepmc   +1 more source

AI‐Driven Acceleration of Fluorescence Probe Discovery

Advanced Science, EarlyView.
We present PROBY, an AI model trained on large‐scale datasets to predict key photophysical properties and accelerate the discovery of target‐specific fluorescent probes. By screening a target‐annotated library, PROBY identifies candidate probes for diverse targets and could guide probe optimization, enabling a range of in vitro and in vivo imaging ...
Xuefeng Jiang, Yanbo Li, Xue Tian, Sen Yang, Ruina Luo, Cenxing Zhou, Yuxuan Liu, Jingying Hu, Sen Feng, Lu Gan, Chongzhao Ran, Kun‐Hsing Yu, Junhan Zhao, Xiao Han, Xuan Zhai, Yuntao Jia, Jiapei Dai, Xiyue Wang, Biyue Zhu   +18 more
wiley   +1 more source

Robot-Assisted Distal Pancreatectomy Using the Hugo RAS System via the Supragastric Approach: First Nationwide Case Report (With Video). [PDF]

Asian J Endosc Surg
Nagai K, Yamane K, Sato A, Nishino H, Nishio T, Sakamoto K, Ogiso S, Uchida Y, Ito T, Ishii T, Hisamori S, Obama K, Hatano E.   +12 more
europepmc   +1 more source

Halorotetin B, A Novel Terpenoid Compound Derived from Marine Ascidian, Suppresses Tumor Growth by Targeting the Cell Cycle Regulator UBE2C

Advanced Science, EarlyView.
Halorotetin B, a novel small‐molecule terpenoid identified from an edible marine ascidian, exhibits strong anti‐tumor activity both in vitro and in vivo through direct targeting UBE2C to induce tumor cell cycle arrest and then lead tumor cell senescence. As a newly discovered UBE2C inhibitor, Halorotetin B can serve as a novel potential cell senescence
Shanhao Han, Jianhui Li, Yuting Zhu, Penghui Liu, Yaoyao Zheng, Muchun He, Bo Dong   +6 more
wiley   +1 more source

Long-Term Survival in a Dog After Adrenalectomy and Splenectomy for Two Different Malignancies with Portal Vein Involvement. [PDF]

Animals (Basel)
Kim SH, Park JG, Yoon JH, Baek YB, Park SI.   +4 more
europepmc   +1 more source

Alkaline Phosphatase‐Activated NIR‐II AIEgens Nanosystem for Surgical and Postoperative Closed‐Loop Therapy of Advanced Osteosarcoma

Advanced Science, EarlyView.
This study designed a tumor microenvironment‐responsive AIEgen nanoparticle for near‐infrared photoimmunotherapy, which inhibits primary tumors and metastasis by promoting pyroptosis and suppressing aerobic glycolysis. ABSTRACT In advanced osteosarcoma, tumor invasion often prevents complete resection, and immunotherapy is limited by the tumor's ...
Kaiyuan Liu, Ruotong Li, Li Zhang, Hengli Lu, Binhui Yang, Qian Hu, Yining Tao, Haoran Mu, Jing Han, Pengfei Zan, Jiakang Shen, Dongqing Zuo, Hongsheng Wang, Wei Sun, Xingjun Zhu   +14 more
wiley   +1 more source

Desmoid tumor causing large bowel obstruction: an extremely rare diagnosis with an innovative treatment approach. [PDF]

J Surg Case Rep
Ibrahim M, Aleter A, Toffaha A, Abdul-Hafez HA, Yousif M, Kurer M.   +5 more
europepmc   +1 more source