Results 141 to 150 of about 394,248 (332)

Recovery of recordings from heat damaged magnetic tapes [PDF]

, 1973
Damaged tapes can now be repaired at home as long as damage does not extend to layer-to-layer adhesion within tape roll. Splice repaired section into good roll or cassette for copying. Every effort should be made to complete copying on first run, because
Melugin, J. F., Obrien, D. E., III
core   +1 more source

Macro and micro polypropylene fiber effect on reinforced concrete beams with insufficient lap splice length

Case Studies in Construction Materials, 2022
For longer spans of reinforced concrete elements, design codes dictate the use of sufficient lap splice length. Insufficient lap splice length decreases the flexural strength and ductility of reinforced concrete (RC) beams, while fiber addition improves ...
Süleyman Kamil Akın, Saruhan Kartal, Abdullah Müsevitoğlu, Sadrettin Sancıoğlu, Ahmad Javid Zia, Abdulkerim İlgün   +5 more
doaj  

In vitro RNA-RNA splicing in adenovirus 2 mRNA formation. [PDF]

, 1978
J. M. Blanchard, Jesse N. Weber, Warren R. Jelinek, James Darnell   +3 more
openalex   +1 more source

The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity

FEBS Open Bio, EarlyView.
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda, Melissa Montrose, Akinori Takahashi, Risa Ishida, Sandrine Burriel, Nao Ohmine, Tohru Natsume, Shungo Adachi, Minsoo Kim, Tadashi Yamamoto   +9 more
wiley   +1 more source

Splicing of SV40 late mRNA is a post-transcriptional process [PDF]

, 1978
Mia Horowitz, Orgad Laub, Susan Bratosin, Yosef Aloni   +3 more
openalex   +1 more source

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

FEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr, Michael Fauler, Thomas Zimmer, Bettina Jungwirth, Hubert Schrezenmeier, David Alexander Christian Messerer   +5 more
wiley   +1 more source

BKV splice sequences based on analysis of preferred donor and acceptor sites [PDF]

, 1979
I. Seif, George Khoury, Ravi Dhar
openalex   +1 more source

Downregulation of sST2, a decoy receptor for interleukin‐33, enhances subcutaneous tumor growth in murine pancreatic cancer cells

FEBS Open Bio, EarlyView.
Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto, Nobuko Koshikawa, Takao Morinaga, Mimi Tamamori‐Adachi, Atsushi Takatori, Keizo Takenaga   +5 more
wiley   +1 more source

Predicting DNA sequence splice site based on graph convolutional network and DNA graph construction

Journal of King Saud University: Computer and Information Sciences
Identifying splice sites is essential for gene structure analysis and eukaryotic genome annotation. Recently, computational and deep learning approaches for splice site detection have advanced, focusing on reducing false positives by distinguishing true ...
Luo Rentao, Li Yelin, Guan Lixin, Li Mengshan   +3 more
doaj  

A Novel CHMP2B Splicing Variant in Atypical Presentation of Familial Frontotemporal Lobar Degeneration

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT C‐truncating variants in the charged multivesicular body protein 2B (CHMP2B) gene are a rare cause of frontotemporal lobar degeneration (FTLD), previously identified only in Denmark, Belgium, and China. We report a novel CHMP2B splice‐site variant (c.35‐1G>A) associated with familial FTLD in Spain. The cases were two monozygotic male twins who
Sara Rubio‐Guerra, Sara Bernal, David Almenta, Josefina Pérez‐Blanco, Valle Camacho, Isabel Sala, Mª Belén Sánchez‐Saudinós, Jesús García Castro, Judit Selma‐González, Miguel Ángel Santos‐Santos, Álvaro Carbayo, Janina Turon‐Sans, Ricard Rojas‐Garcia, Daniel Alcolea, Juan Fortea, Alberto Lleó, Oriol Dols‐Icardo, Ignacio Illán‐Gala   +17 more
wiley   +1 more source