Results 191 to 200 of about 395,684 (337)

The DEAH-box splicing factor Prp16 unwinds RNA duplexes in vitro [PDF]

, 1998
Yan Wang, John D. Wagner, Christine Guthrie   +2 more
openalex   +1 more source

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

Advanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen, Zichen Liu, Mengyi Wei, Qian Li, Liang Wu, Kunyuan Yu, Yanhong Xu, Dainan Yu, Wenwu Ma, Hongmei Wang, Ng Shyh‐Chang, Jinglei Zhai   +11 more
wiley   +1 more source

KChIP1 splice variants modulate Kv4 channels by promoting P/C-type inactivation features. [PDF]

Sci Rep
Cao W, Tachtsidis G, Bähring R.
europepmc   +1 more source

Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier

Advanced Science, EarlyView.
SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao, Aiting Wang, Yue Xu, Wenxin Feng, Chunxiao Ma, Ziyi Wang, Wei Zhang, Wenqiong Su, Xiuying Xiao, Wei‐Qiang Gao, Xianting Ding, Li Li   +11 more
wiley   +1 more source

Widespread naturally variable human exons aid genetic interpretation. [PDF]

Nat Commun
Jacobs HN, Gorissen BL, Guez J, Kanai M, Gupta K, Finucane HK, Karczewski KJ, Burge CB.   +7 more
europepmc   +1 more source

P-coumaric acid regulates exon 12 splicing of the ATP7B gene by modulating hnRNP A1 protein expressions

Ying‐Ju Lin, Tsung‐Jung Ho, Ting-Hsu Lin, Wei-Yi Hsu, Shao-Mei Huang, Chiu-Chu Liao, Chih‐Ho Lai, Xiang Liu, Hsinyi Tsang, Chien‐Chen Lai, Fuu‐Jen Tsai   +10 more
openalex   +2 more sources

Synthesis and physiological activity of heterodimers comprising different splice forms of vascular endothelial growth factor and placenta growth factor [PDF]

, 1996
Ralf Birkenhäger, Bernard Schneppe, Wolfgang Röckl, Jörg Wilting, Herbert A. Weich, John E.G. McCarthy   +5 more
openalex   +1 more source

HPD is an m6A Methyltransferase that Protects Colorectal Cancer Cells from Ferroptotic Cell Death by m6A Methylating SLC7A11/GPX4

Advanced Science, EarlyView.
This study reveals that the tyrosine metabolic enzyme HPD functions as a previously uncharacterized, METTL3‐independent m6A methyltransferase. It promotes colorectal tumor progression by coordinately regulating the SLC7A11/GPX4 axis to suppress ferroptosis.
Jiyan Wang, Xintong Dai, Huanle Liu, Saiwei Hua, Hongkai Chang, Huanran Sun, Mingming Sun, Huifang Zhao, Kemin Ni, Fei Xie, Yaya Qiao, Qingle Gao, Chenxi Yu, Qijun Zhang, Jianshuang Guo, Chunze Zhang, Shuai Zhang, Changliang Shan   +17 more
wiley   +1 more source

Retraction notice to "CREB1 promotes cholangiocarcinoma metastasis through transcriptional regulation of the LAYN-mediated TLN1/β1 integrin axis" [Heliyon 10 (2024) e36595]. [PDF]

Heliyon
Liang S, Zhou S, Tang Y, Xiao M, Ye K.
europepmc   +1 more source

Bone Dysplasia as a Key Feature in Three Patients with a Novel Congenital Disorder of Glycosylation (CDG) Type II Due to a Deep Intronic Splice Mutation in TMEM165

, 2012
Renate Zeevaert, Francis de Zegher, Luisa Sturiale, Domenico Garozzo, Maria-Helena Smet, Marian Moens, Gert Matthijs, J. Jaeken   +7 more
openalex   +2 more sources