Results 31 to 40 of about 394,248 (332)
An experimental investigation on contact compression lap splice in circular columns
HBRC Journal, 2016 Due to the rapid development in design of multistory buildings and, because of the variation in stories height with the fixed length of the steel reinforcing bars, steel is usually wasted particularly in columns. Hence, compression lap splice may be used
Hamed S. Askar
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Exon sequences at the splice junctions affect splicing fidelity and alternative splicing [PDF]
Proceedings of the National Academy of Sciences, 2009 Identification of splice sites is essential for the expression of most eukaryotic genes, allowing accurate splicing of pre-mRNAs. The splice sites are recognized by the splicing machinery based on sequences within the pre-mRNA. Here, we show that the exon sequences at the splice junctions play a significant, previously unrecognized role in the ...
Luciana B. Crotti, David S. Horowitz
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αCP binding to a cytosine-rich subset of polypyrimidine tracts drives a novel pathway of cassette exon splicing in the mammalian transcriptome. [PDF]
, 2016 Alternative splicing (AS) is a robust generator of mammalian transcriptome complexity. Splice site specification is controlled by interactions of cis-acting determinants on a transcript with specific RNA binding proteins.
Bahrami-Samani, Emad +7 more
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Prediction and Quantification of Splice Events from RNA-Seq Data.
PLoS ONE, 2016 Analysis of splice variants from short read RNA-seq data remains a challenging problem. Here we present a novel method for the genome-guided prediction and quantification of splice events from RNA-seq data, which enables the analysis of unannotated and ...
Leonard D Goldstein +6 more
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Noisy splicing drives mRNA isoform diversity in human cells. [PDF]
PLoS Genetics, 2010 While the majority of multiexonic human genes show some evidence of alternative splicing, it is unclear what fraction of observed splice forms is functionally relevant.
Joseph K Pickrell +3 more
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Splicing and alternative splicing in rice and humans
BMB Reports, 2013 Rice is a monocot gramineous crop, and one of the most important staple foods. Rice is considered a model species for most gramineous crops. Extensive research on rice has provided critical guidance for other crops, such as maize and wheat. In recent years, climate change and exacerbated soil degradation have resulted in a variety of abiotic stresses ...
Lei Wang, Jianhua Zhou, Zhiguo E
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SpliceFinder: ab initio prediction of splice sites using convolutional neural network
BMC Bioinformatics, 2019 Background Identifying splice sites is a necessary step to analyze the location and structure of genes. Two dinucleotides, GT and AG, are highly frequent on splice sites, and many other patterns are also on splice sites with important biological ...
Ruohan Wang +3 more
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Complex surface singularities with integral homology sphere links [PDF]
, 2005 While the topological types of {normal} surface singularities with homology sphere link have been classified, forming a rich class, until recently little was known about the possible analytic structures. We proved in [Geom. Topol.
Barth +19 more
core +6 more sources
Molecular Cell, 2007 A novel study in a recent issue of Molecular Cell (Shi and Manley, 2007) provides insight into a complex signaling pathway that controls the phosphorylation status of an SR-related protein that functions as a splicing repressor following heat shock-dependent dephosphorylation.
Guil, Sonia, Cáceres, Javier F.
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Computational and Structural Biotechnology Journal, 2021 Codon degeneracy of amino acid sequences permits an additional “mRNP code” layer underlying the genetic code that is related to RNA processing. In pre-mRNA splicing, splice site usage is determined by both intrinsic strength and sequence context ...
Johannes Ptok +6 more
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