Results 71 to 80 of about 394,248 (332)
FEBS Letters, EarlyView.In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi +5 more
wiley +1 more source
Assessing conservation of alternative splicing with evolutionary splicing graphs [PDF]
Genome Research, 2020 Understanding how protein function has evolved and diversified is of great importance for human genetics and medicine. Here, we tackle the problem of describing the whole transcript variability observed in several species by generalizing the definition of splicing graph.
Hugues Richard +5 more
openaire +8 more sources
Recessive osteogenesis imperfecta caused by LEPRE1 mutations: clinical documentation and identification of the splice form responsible for prolyl 3-hydroxylation [PDF]
, 2009 : Background: Recessive forms of osteogenesis imperfecta (OI) may be caused by mutations in LEPRE1, encoding prolyl 3-hydroxylase-1 (P3H1) or in CRTAP, encoding cartilage associated protein.
Coucke, Paul +9 more
core +2 more sources
Alexandria Engineering Journal, 2016 This paper presents an experimental investigation on the behavior and strength of reinforced concrete slabs with lap splice of tension reinforcement using headed bars.
Ahmed M. Tarabia +3 more
doaj +1 more source
Effect of Distance between Two Optical Single Mode Fibers on Minimum Splice Losses by Using Arc Fusion Splicer [PDF]
Engineering and Technology Journal, 2014 Old Researches were worked to find the splice losses between two single mode fibers (SMF-28/SMF-28) by using different arc fusion splicer without taking the effect of distance between them.
Salah Aldeen Adnan Taha
doaj +1 more source
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
FEBS Letters, EarlyView.Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää +2 more
wiley +1 more source
Invariance of the Cuntz splice
, 2016 We show that the Cuntz splice induces stably isomorphic graph $C^*$-algebras.Comment: Our arguments to prove invariance of the Cuntz splice for unital graph C*-algebras in arXiv:1505.06773 applied with only minor changes in the general case.
Eilers, Søren +3 more
core +1 more source
iCLIP predicts the dual splicing effects of TIA-RNA interactions.
PLoS Biology, 2010 The regulation of alternative splicing involves interactions between RNA-binding proteins and pre-mRNA positions close to the splice sites. T-cell intracellular antigen 1 (TIA1) and TIA1-like 1 (TIAL1) locally enhance exon inclusion by recruiting U1 ...
Zhen Wang +8 more
doaj +1 more source
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
FEBS Letters, EarlyView.The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen +2 more
wiley +1 more source
Discrete Applied Mathematics, 1996 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources