Results 81 to 90 of about 394,248 (332)

Spliced-Leader trans-Splicing in Freshwater Planarians [PDF]

Molecular Biology and Evolution, 2005
trans-Splicing, in which a spliced-leader (SL) RNA is appended to the most 5' exon of independently transcribed pre-mRNAs, has been described in a wide range of eukaryotes, from protozoans to chordates. Here we describe trans-splicing in the freshwater planarian Schmidtea mediterranea, a free-living member of the phylum Platyhelminthes.
Ricardo M. Zayas, Tyler D. Bold, Phillip A. Newmark   +2 more
openaire   +3 more sources

Mammalian Septins Nomenclature [PDF]

, 2002
There are 10 known mammalian septin genes, some of which produce multiple splice variants. The current nomenclature for the genes and gene products is very confusing, with several different names having been given to the same gene product and distinct ...
Kennedy, Mary B., Macara, Ian G.
core  

Finite mixture clustering of human tissues with different levels of IGF-1 splice variants mRNA transcripts [PDF]

, 2015
BACKGROUND: This study addresses a recurrent biological problem, that is to define a formal clustering structure for a set of tissues on the basis of the relative abundance of multiple alternatively spliced isoforms mRNAs generated by the same gene.
Alfo', Marco, Martella, Francesca, Musaro', Antonio, Pappalardo, E., Pelosi, M.   +4 more
core   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Characteristics of transposable element exonization within human and mouse [PDF]

, 2010
Insertion of transposed elements within mammalian genes is thought to be an important contributor to mammalian evolution and speciation. Insertion of transposed elements into introns can lead to their activation as alternatively spliced cassette exons ...
A Athanasiadis, A Corvelo, A Gerber, A Goren, A Levy, A Magen, A Nekrutenko, A Resch, AFA Smit, Agnes Hotz-Wagenblatt, B Giardine, B Mersch, BR Graveley, Britta Mersch, C Liu, D Karolchik, D Labuda, DD Kim, E Kim, ES Lander, EY Levanon, G Ast, G Lev-Maor, G Lev-Maor, Gil Ast, H Xie, Ilya Ruvinsky, J Hull, J Jurka, J Jurka, JO Kriegs, JO Yang, JP Nemes, K Nakabayashi, KP Kister, L Lin, L Lin, M Amit, M Blow, M Krull, M Moller-Krull, M Roy, M Sironi, M Sironi, MA Batzer, MD Koob, N Gal-Mark, N Gal-Mark, N Sela, NH Gehring, Noa Sela, O Ram, P Deininger, PL Deininger, R Cordaux, R Sorek, R Sorek, R Sorek, RA Gibbs, RE Mills, RH Waterston, RM Kuhn, RT Hillman, S He, S Schwartz, SK Ng, SS Singer, ST Sherry, T Kwan, T Kwan, VV Kapitonov, W Makalowski, WJ Kent, WL Chen, WS Lo, XH Zhang, Y Xing, YF Chang   +77 more
core   +4 more sources

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

RNA-Seq analysis of splicing in Plasmodium falciparum uncovers new splice junctions, alternative splicing and splicing of antisense transcripts. [PDF]

, 2011
Over 50% of genes in Plasmodium falciparum, the deadliest human malaria parasite, contain predicted introns, yet experimental characterization of splicing in this organism remains incomplete.
DeRisi, Joseph L, Dimon, Michelle T, Sorber, Katherine   +2 more
core   +3 more sources

SOAPsplice: genome-wide ab initio detection of splice junctions from RNA-Seq data

Frontiers in Genetics, 2011
RNA-Seq, a method using next generation sequencing technologies to sequence the transcriptome, facilitates genome-wide analysis of splice junction sites.
Songbo eHuang, Songbo eHuang, Jinbo eZhang, Ruiqiang eLi, Wenqian eZhang, Zengquan eHe, Tak-Wah eLam, Zhiyu ePeng, Siu-Ming eYiu   +8 more
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Determining When The Universal Abelian Cover of a Graph Manifold is a Rationla Homology Sphere [PDF]

, 2010
It was shown in my earlier article that the splice diagram of a rational homology sphere graph manifold determines the manifolds universal abelian cover. In this article we use the proof of this to give a condition on the splice diagram to determine when
Pedersen, Helge Møller
core