Results 231 to 240 of about 483,589 (358)

Pharmacological CLK inhibition disrupts SR protein function and RNA splicing blocking cell growth and migration in TNBC. [PDF]

Breast Cancer Res
Liu N, van der Velde JJS, Ramdjielal S, Koedoot E, van Overbeek NK, Batenburg D, Vertegaal ACO, van de Water B, Le Dévédec SE.   +8 more
europepmc   +1 more source

A novel role for the 3' region of introns in pre-mRNA splicing of Saccharomyces cerevisiae. [PDF]

, 1987
Brian C. Rymond, Dana Torrey, Michael Rosbash   +2 more
openalex   +1 more source

RNA mis-splicing in disease

Nature reviews genetics, 2015
M. Scotti, M. Swanson
semanticscholar   +1 more source

Organization of the Proteostasis Network of Membraneless Organelles

Advanced Science, EarlyView.
A comprehensive mapping of the proteostasis network (PN) across membraneless organelles (MLOs) reveals how central PN components coordinate MLO regulation. The analysis uncovers principles of specificity and promiscuity within the PN. The findings suggest that HSP70 chaperones act as generic MLO regulators, while client specific HSP70 co‐chaperones may
Christine M. Lim, Yuqi Bian, Alicia González Díaz, Frank Pun, Alex Zhavoronkov, Richard I. Morimoto, Michele Vendruscolo   +6 more
wiley   +1 more source

A novel intronic variant in the ASAH1 gene enhances aberrant splicing, causing spinal muscular atrophy with progressive myoclonic epilepsy. [PDF]

Ital J Pediatr
Bai J, Li P, Jiao H, Jin Y, Wang H, Jiang Q, Song F, Peng X, Qu Y.   +8 more
europepmc   +1 more source

Platelet-derived growth factor A chain: gene structure, chromosomal location, and basis for alternative mRNA splicing.

, 1988
David T. Bonthron, Cynthia C. Morton, Stuart H. Orkin, Teresa Collins   +3 more
openalex   +1 more source

Gene structure for the alpha 1 chain of a human short-chain collagen (type XIII) with alternatively spliced transcripts and translation termination codon at the 5' end of the last exon. [PDF]

, 1988
Liisa Tikka, Taina Pihlajaniemi, Pirkko Henttu, Darwin J. Prockop, Karl Tryggvason   +4 more
openalex   +1 more source

Novel Antimicrobial Protein Fibroblast Growth Factor 8 Accelerates Skin Wound Healing via Directly Inhibiting Bacteria and Activating Glycolysis

Advanced Science, EarlyView.
Wound infections induce gcFGF8a expression, which subsequently executes direct antimicrobial activity to suppress local infection while simultaneously activating the FGFR4‐mediated ERK/AKT‐mTOR signaling cascade, thereby upregulating HIF1α and enhancing glycolysis. These coordinated actions synergistically promote tissue repair by eliminating pathogens
Ya‐Zhen Hu, Ting Wang, Chang‐Song Wu, Jie Wang, Xue‐Qing Han, Yong‐An Zhang, Xu‐Jie Zhang   +6 more
wiley   +1 more source

Dynamic Coordination of Alternative Splicing and Subgenome Expression Bias Underlies Rusty Root Symptom Response in <i>Panax ginseng</i>. [PDF]

Plants (Basel)
Zhao J, Li J, Lei X, Di P, Xun H, Zhang Z, Zhang J, Meng X, Wang Y.   +8 more
europepmc   +1 more source

Group II intron self-splicing. Alternative reaction conditions yield novel products.

, 1988
Kevin A. Jarrell, Craig L. Peebles, Rosemary C. Dietrich, Steven L. Romiti, Philip S. Perlman   +4 more
openalex   +1 more source