Results 231 to 240 of about 603,390 (338)

Immunologically distinct p53 molecules generated by alternative splicing.

open access: green, 1986
Nobuyuki Arai   +6 more
openalex   +1 more source

Human CSF-1: gene structure and alternative splicing of mRNA precursors. [PDF]

open access: bronze, 1987
Martha Ladner   +6 more
openalex   +1 more source

BLOC1S1 Attenuates B. Melitensis 16M LPS‐Triggered Autophagy by Spatial Confinement of TDP‐43

open access: yesAdvanced Science, EarlyView.
This study explores how B. melitensis 16M LPS and BLOC1S1 regulate autophagy in goat spermatogonial stem cells. The 16M LPS is activating AMPK‐dependent autophagy, increasing LC3B‐II/I ratios and lysosomal genes, while Escherichia coli LPS shows no effect.
Shicheng Wan   +13 more
wiley   +1 more source

Evidence that introns arose at proto-splice sites. [PDF]

open access: green, 1989
N. J. Dibb, Andrew J. Newman
openalex   +1 more source

Gene Editing of a Susceptibility LncRNA Enhances Broad‐Spectrum Disease Resistance in Rice without Developmental Trade‐Offs

open access: yesAdvanced Science, EarlyView.
Editing susceptibility lncRNAs offers a strategy to enhance disease resistance without yield loss. RESIS, a domestication‐acquired, pathogen‐induced lncRNA, promotes protein N‐terminal acetylation through its interaction with NatA complex. Knockout of RESIS increases translation and confers broad‐spectrum resistance to both fungal and bacterial ...
Wen‐long Zhao   +17 more
wiley   +1 more source

Editorial: RNA Splicing and Backsplicing: Disease and Therapy

open access: yesFrontiers in Genetics, 2020
Rosanna Asselta   +6 more
doaj   +1 more source

Elevated Apolipoprotein E Expression in Hippocampal Microglia Drives Temporal Lobe Epilepsy Progression

open access: yesAdvanced Science, EarlyView.
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi   +10 more
wiley   +1 more source

In-vitro human myogenesis model reveals novel mRNA alternative splicing isoforms. [PDF]

open access: yesSci Rep
Donega S   +11 more
europepmc   +1 more source

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