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Sweet splicing

Cell, 2023
Glucose is the main source of energy for cells. In this issue of Cell, a study now shows that glucose has additional non-energetic functions, acting as a biomolecular cue that regulates alternative splicing during epidermal differentiation. As keratinocytes differentiate, glucose associates with RNA-binding protein DDX21 and modulates its interaction ...
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SPLiCE

Proceedings of the 2nd ACM SIGHIT International Health Informatics Symposium, 2012
In face of well-known inhibitor factors for the dissemination of Healthcare Information Systems (HIS) - "e.g., high development cost, lack of standardization, and technology-orientation" - model-driven engineering (MDE) in general, and OMG's model-driven architecture (MDA) in particular, has been referred to in the medical informatics literature as a ...
Antônio Tadeu Azevedo Gomes   +4 more
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Spliced leader RNA trans-splicing in metazoa

Parasitology Today, 1996
Spliced leader trans-splicing is a form of RNA processing originally described and studied in parasitic kinetoplastida. This mechanism of gene expression also occurs in parasitic and free-living metazoa. In this review, Dick Davis describes current knowledge of the distribution, substrates, specificity and functional significance of trans-splicing in ...
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Plant pre-m RNA splicing and splicing components

Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 1993
Pre-mRNA splicing or the removal of introns from precursor messenger RNAs depends on the accurate recognition of intron sequences by the plant splicing machinery. The major components of this machinery are small nuclear ribonucleoprotein protein particles (snRNPs) which consist of snRNAs and snRNP proteins. We have analysed various aspects
J W, Brown   +4 more
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Editorial – splicing and alternative splicing

The International Journal of Biochemistry & Cell Biology, 2019
Jose-Luis, Capelo-Martinez   +3 more
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