Results 41 to 50 of about 130,317 (268)
Advanced Science, EarlyView.A biomimetic artificial intelligence system, PancDS, has been developed to distinguish pancreatic ductal adenocarcinoma from mass‐forming pancreatitis by adaptively integrating clinical data, radiomics, and deep learning features. Validated across multicenter, reader‐study, and prospective settings, PancDS improves diagnostic accuracy, particularly for
Zhibo Wang +13 more
wiley +1 more source
A rational cubic spline with tension
, 1989 A rational cubic spline curve is described which has tension control parameters for manipulating the shape of the curve. The spline is presented in both interpolatory and rational B-spline forms, and the behaviour of the resulting representations is ...
Gregory, JA, Sarfraz, M
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Advanced Science, EarlyView.This study establishes a CT‐based radiomics framework to quantify intratumoral heterogeneity (ITH) in HNSCC. Using unsupervised clustering, tumor ROIs and VOIs are analyzed to calculate 2D/3D ITH scores. The score shows strong predictive value for prognosis and immunotherapy response, and is associated with tumor metabolism and immune microenvironment,
Xinwei Chen +15 more
wiley +1 more source
Advanced Science, EarlyView.Low‐level ambient benzene exposure is associated with increased risks of multiple brain disorders in urban adults. Genetic susceptibility modifies these associations, while plasma proteomics points to potential biological pathways linking benzene exposure to adverse brain health.
Jianhui Guo +10 more
wiley +1 more source
USING SPLINE FUNCTIONS FOR THE SUBSTANTIATION OF TAX POLICIES BY LOCAL AUTHORITIES [PDF]
The paper aims to approach innovative financial instruments for the management of public resources. In the category of these innovative tools have been included polynomial spline functions used for budgetary sizing in the substantiating of fiscal and ...
Bolos Marcel, Otgon Cristian, Pop Razvan
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stMixer for Scalable Mosaic Integration and Label Transfer in Spatial Histology and Multi‐Omics
Advanced Science, EarlyView.stMixer is an unsupervised framework for scalable integration and label transfer across spatial histology and multi‐slide multi‐omics data with incomplete modality overlap. It combines self‐looped cross‐attention, multimodal metric learning, and graph‐guided cluster voting to align heterogeneous sections, correct batch effects, and propagate ...
Qixing Yang +3 more
wiley +1 more source
Quartic spline-on-spline interpolation
Journal of Computational and Applied Mathematics, 1996 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Xieping-Gao, , Shi-Shu, , Kaixin-Fu,
openaire +1 more source
The weighted v-spline as a double knot B-spline
, 1991 The local support basis representation of the ‘weighted v-spline’ is derived in terms of double knot cubic B-splines, so providing a convenient form for computing and analysing the ...
Gregory, JA, Zhou, J
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Mechanical Activation of Piezo1 Drives Osteoarthritis Through Kdm5c‐Mediated Epigenetic Silencing
Advanced Science, EarlyView.Excessive mechanical stress activates Piezo1, triggering Ca2+‐dependent cytoskeletal forces that deform the nucleus and reduce H3K4me3. Kdm5c demethylates H3K4me3 at Col2a1 and Runx3 promoters. Kdm5c knockout rescues degradation. Repurposed telmisartan directly inhibits Kdm5c, blocking this axis and showing disease‐modifying efficacy in mouse OA models
Tianyou Kan +13 more
wiley +1 more source
Cubic spline interpolation of harmonic functions
, 1973 It is shown that for the two dimensional Laplace equation a univariate cubic spline approximation in either space direction together with a difference approximation in the other leads to the well-known nine-point finite-difference formula.
Whiteman, J R, Papamichael, N
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