Results 81 to 90 of about 101,819 (267)
Advanced Science, EarlyView.Employing a digital single‐molecule activity tracker (dSMAT), this research demonstrates that high‐photon‐flux irradiation drives progressive oxidative scarring in polymerases. Unlike simple thermal denaturation, real‐time kinetic tracking dynamically visualizes enzymes degrading into multiple impaired subpopulations.
Anran Zheng +11 more
wiley +1 more source
The Wear Behaviour of a New Eccentric Meshing Reducer with Small Teeth Difference
MachinesEccentric meshing reducers are widely used in agriculture, industrial robots, and other fields due to their ability to achieve a high reduction ratio within a compact volume.
Renqiang Yang +5 more
doaj +1 more source
Advanced Science, EarlyView.Bioinspired passive flow routing mitigates thrombosis in cardiovascular devices by redirecting a small fraction of forward flow into stagnation‐prone regions. Inspired by avian alula and aircraft slat mechanisms, strategically placed routing channels restore washout around mechanical heart valves, reducing low‐shear exposure by four orders of magnitude
Yevgeniy Kreinin +8 more
wiley +1 more source
Nauka ta progres transportu, 2015 Purpose. Today the issue, connected with diesel traction remains relevant for the majority of industrial enterprises and Ukrainian railways and diesel engine continues to be the subject of extensive research and improvements.
M. I. Kapitsa +3 more
doaj +1 more source
Splines and vector splines [PDF]
, 1997 The thrust of this report concerns spline theory and some of the background to spline theory and follows the development in (Wahba, 1991). We also review methods for determining hyper-parameters, such as the smoothing parameter, by Generalised Cross Validation.
openaire
Multiscale Circuit Architecture Associated With Memory Dysfunction in Temporal Lobe Epilepsy
Advanced Science, EarlyView.A multiscale precision‐mapping framework reveals that memory impairment in temporal lobe epilepsy arises from the convergence of focal medial temporal pathology, strategic white matter disconnection, and limbic‐centered metabolic network dysfunction.
Jiajie Mo +12 more
wiley +1 more source
Investigation on bending moment capacity of corner joints constructed with spline under diagonal tension and compression [PDF]
Iranian Journal of Wood and Paper Industries, 2018 This study was conducted to evaluate the effects of the penetration depths (8, 11, 14) and material types of spline (high density fiber board (HDF), plywood and hornbeam wood (Carpinus betulus)) composite material types (MDF and particleboard) on bending
kambiz rashedi
doaj
Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance
Advanced Science, EarlyView.Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer +9 more
wiley +1 more source
IEEE Transactions on Neural Systems and Rehabilitation EngineeringFreezing of gait (FoG) is an episodic symptom that disrupts walking initiation in patients with Parkinson’s disease (PD). Identifying pre-FoG stages is crucial for patients with PD.
Yi-Ting Hwang +7 more
doaj +1 more source
A Panel of Circulating Exosomal sncRNAs Associated With Lung Cancer Risk up to 10 Years in Advance
Advanced Science, EarlyView.Lung cancer is often diagnosed too late, and current screening overlooks many people at risk. In a long‐term study of smokers, a panel of small non‐coding RNAs carried in blood exosomes signals elevated lung cancer risk up to ten years before diagnosis, pointing toward a blood‐based tool for earlier risk detection.
Zhuokun Feng +12 more
wiley +1 more source