Results 71 to 80 of about 101,819 (267)

Long‐Term Ambient Benzene Exposure and Brain Disorders Among Urban Adults: Effect Modification by Genetic Susceptibility and Potential Mediation by Plasma Proteins

Advanced Science, EarlyView.
Low‐level ambient benzene exposure is associated with increased risks of multiple brain disorders in urban adults. Genetic susceptibility modifies these associations, while plasma proteomics points to potential biological pathways linking benzene exposure to adverse brain health.
Jianhui Guo, Xia Zhong, Petros Koutrakis, Carolina L. Zilli Vieira, Feifei Si, Yaqi Wang, Xinyao Lian, Yi Fan, Zhaokun Wang, Shaodan Huang, Jing Li   +10 more
wiley   +1 more source

stMixer for Scalable Mosaic Integration and Label Transfer in Spatial Histology and Multi‐Omics

Advanced Science, EarlyView.
stMixer is an unsupervised framework for scalable integration and label transfer across spatial histology and multi‐slide multi‐omics data with incomplete modality overlap. It combines self‐looped cross‐attention, multimodal metric learning, and graph‐guided cluster voting to align heterogeneous sections, correct batch effects, and propagate ...
Qixing Yang, Yan Wang, Luonan Chen, Chunman Zuo   +3 more
wiley   +1 more source

Mechanical Activation of Piezo1 Drives Osteoarthritis Through Kdm5c‐Mediated Epigenetic Silencing

Advanced Science, EarlyView.
Excessive mechanical stress activates Piezo1, triggering Ca2+‐dependent cytoskeletal forces that deform the nucleus and reduce H3K4me3. Kdm5c demethylates H3K4me3 at Col2a1 and Runx3 promoters. Kdm5c knockout rescues degradation. Repurposed telmisartan directly inhibits Kdm5c, blocking this axis and showing disease‐modifying efficacy in mouse OA models
Tianyou Kan, Xuran Li, Han Wang, Lin Sun, Yao Wang, Jiangdong Wu, Junqi Cui, Yiqi Yang, Kai Yuan, Linyang Chu, Liao Wang, Hanjun Li, Mengning Yan, Zhifeng Yu   +13 more
wiley   +1 more source

Smooth joining of spline curves ensuring a high order of smoothness

Омский научный вестник
Smoothly blending two curves is one of the fundamental and complex problems of geometric modeling in computer-aided design systems. This article proposes a method for constructing a smoothly blended curve between two spline curves of arbitrary format and
V. G. Mufteev, F. T. Ziganshina, V. I. Gumerov   +2 more
doaj   +1 more source

Quartic spline-on-spline interpolation

Journal of Computational and Applied Mathematics, 1996
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Xieping-Gao, , Shi-Shu, , Kaixin-Fu,
openaire   +1 more source

An exciting Approach to Theoretical Spectroscopy

Advanced Science, EarlyView.
ABSTRACT Theoretical spectroscopy, and more generally, electronic‐structure theory, are powerful concepts for describing the complex many‐body interactions in materials. They cover methods from ground‐state properties to lattice excitations and light‐matter interaction, including time‐resolved variants.
Martí Raya‐Moreno, Alexander Buccheri, Noah Alexy Dasch, Nasrin Farahani, Ignacio Gonzalez Oliva, Andris Gulans, Seokhyun Hong, Manoar Hossain, Hannah Kleine, Martin Kuban, Sven Lubeck, Benedikt Maurer, Pasquale Pavone, Fabian Peschel, Daria Popova‐Gorelova, Lu Qiao, Elias Richter, Santiago Rigamonti, Ronaldo Rodrigues Pela, Maximilian Schebek, Kshitij Sinha, Daniel T. Speckhard, Jan Stutz, Sebastian Tillack, Dmitry Tumakov, Jānis Užulis, Mara Voiculescu, Cecilia Vona, Mao Yang, Claudia Draxl   +29 more
wiley   +1 more source

Design of Wheel-axle Transmission Scheme for High-speed Variable-gauge EMU Bogies

机车电传动, 2020
In view of the problem of torque transmission between wheels and axles of high-speed variable-gauge EMU bogies, three transmission schemes were put forward, which were roller spline transmission scheme, spline shaft transmission scheme and sleeve spline ...
Feifei HU, Zhihui HUANG, Zhiwei ZHENG
doaj  

Physics‐Informed Neural Network‐Enabled Forward Prediction and Inverse Design of Ring Origami

Advanced Science, EarlyView.
This work presents a KRT‐PINN framework that integrates Kirchhoff rod theory with physics‐informed neural networks for the forward prediction and inverse design of ring origami consisting of closed‐loop rods. The framework predicts stable states of segmented rings with prescribed natural‐curvature profiles and determines the natural‐curvature profiles ...
Luyuan Ning, Lu Lu, Sophie Leanza, Ruike Renee Zhao   +3 more
wiley   +1 more source

Wearable‐Derived Diurnal Alignment Between Physical Activity and Device Temperature Predicts Future Disease and Mortality Risk

Advanced Science, EarlyView.
Wearable‐derived diurnal alignment between physical activity and device temperature, decomposed into 24 h coupling strength (M24), phase deviation (D24), and 12 h harmonic magnitude (M12), is examined in approximately 90,000 UK Biobank participants.
Han Chen, Jiahe Wei, Jonathan Cedernaes, Christian Benedict, Athanasios Tsanas, Zhi Cao, Xiao Tan   +6 more
wiley   +1 more source

Tangled Splines

CoRR, 2016
Extracting shape information from object bound- aries is a well studied problem in vision, and has found tremen- dous use in applications like object recognition. Conversely, studying the space of shapes represented by curves satisfying certain constraints is also intriguing.
openaire   +2 more sources