Results 91 to 100 of about 965,525 (281)

Unbalanced and Minimal Point Equivalent Estimation Second-Order Split-Plot Designs [PDF]

open access: yes
Restricting the randomization of hard-to-change factors in industrial experiments is often performed by employing a split-plot design structure. From an economic perspective, these designs minimize the experimental cost by reducing the number of resets ...
Kowalski, Scott M.   +2 more
core   +1 more source

A Simulated Study Of Smallholder Dairy Production Systems [PDF]

open access: yes, 1989
Four experiments were conducted to investigate the productive performance of Sahiwal-Friesian cows under different feeding managements. Rotational grazing at stocking rate 6.25 milking cows ( AU ) / ha on Setaria splendida and stall- fed cut Panicum ...
Soetrisno, R. Djoko
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Pertumbuhan Dan Produksi Jagung Manis (Zea Mays Sacaratha Sturt. L) Pada Berbagai Jarak Tanam Dan Waktu Olah Tanah [PDF]

open access: yes, 2013
The aim of the research was to evaluate the growth and production of sweet corn (Zea mays sacharata Sturt. L) planted at various distance and land preparation (soil tillage prior to planting).
Ginting, J. (Jasmani)   +2 more
core  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Response Surface Splitplot Designs: A Literature Review [PDF]

open access: yes
The fundamental principles of experiment design are factorization, replication, randomization, and local control of error. In many industrial experiments, however, departure from these principles is commonplace.
Cortes, Luis A.   +2 more
core   +1 more source

Application and Ethephon of Calcium Chloride for Improving the Fruit Quality of Pineapple [PDF]

open access: yes, 2013
The objective of research was to obtain the treatment time of CaCl2 applications, dosage of CaCl2 and ethephon applications to improve the fruit quality of pineapple. This research used Split-Split Plot Design and each treatment replicated 3times.
Astutl, N. K. (Nungki)   +2 more
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

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