Results 121 to 130 of about 965,525 (281)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Respons Pertumbuhan Dan Produksi Bibit G2 Kentang (Solanum Tuberosum L.) Akibat Perbedaan Bobot Umbi Bibit (G1) Dan Konsentrasi Pupuk Organik Cair Di Rumah Kasa [PDF]
, 2014 The research was conducted at Screen house Experiment Berastagi at ± 1340 m asl from April untilJuly 2013 using split plot design with main plot, i.e. organic liquid fertilizer concentration (0, 2, 4,and 6 mL/L) and sub plot is tuber weight difference (≤
br. Marpaung, Agustina br +3 more
core
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Testing for lack of fit in blocked and split-plot response surface designs
Textbooks on response surface methodology emphasize the importance of lack-of-fit tests when fitting response surface models, and stress that, to be able to test for lack of fit, designed experiments should have replication and allow for pure-error ...
Gilmour, Steven G.
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Paired split-plot designs of multireader multicase studies. [PDF]
J Med Imaging (Bellingham), 2018 Chen W, Gong Q, Gallas BD.
europepmc +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Analysis of a Split-Plot Experimental Design Applied to a Low-Speed Wind Tunnel Investigation [PDF]
A procedure to analyze a split-plot experimental design featuring two input factors, two levels of randomization, and two error structures in a low-speed wind tunnel investigation of a small-scale model of a fighter airplane configuration is described in
Erickson, Gary E.
core +1 more source
Optimization of Gas Sensors Based on Advanced Nanomaterials through Split-Plot Designs and GLMMs. [PDF]
Sensors (Basel), 2018 Berni R, Bertocci F.
europepmc +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source