Results 81 to 90 of about 621,908 (253)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

EFFECTS OF ROW SPACING AND SEEDING RATES ON SOME AGRONOMICAL TRAITS OF SPRING CANOLA (BRASSICA NAPUS L.) CULTIVARS [PDF]

open access: yesJournal of Central European Agriculture, 2009
The objective of the study was to evaluate the effects of row spacing and seeding rates on agronomical traits of three spring canola (Brassica napus L.) cultivars in Iran during 2003-2004. Traits evaluated were plant height, number of seeds pod-1, number
Yazdifar SHAHIN, Ramea VALIOLLAH
doaj  

Physiological and agronomic responses of maize (Zea maysL) cultivars to plant population and defoliation at post-anthesis in the humid rainforest

open access: yesActa Agriculturae Slovenica, 2018
Variations in response pattern of maize (Zea mays)grown at plant populations, defoliated at post-anthesis in the rainforest were tested. Two field trials were conducted at Abeokuta, (Longitude 3025’E, Latitude 7015’N; 144 m a.s.l) and Ibadan (3056’E ...
Olalekan Suleiman SAKARIYAWO   +3 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

The Waterlogging Tolerance of Wheat Varieties in Western of Turkey

open access: yesThe Scientific World Journal, 2012
This research was conducted to determine the wheat varieties against waterlogging which was clearly increased in recent years. For this purpose, this study was performed at Field Crops and Soil Science Department of Agricultural Faculty of Adnan Menderes
Ilkay Yavas, Aydin Unay, Mehmet Aydin
doaj   +1 more source

Efficiency of incomplete split-plot designs – a compromise between traditional split-plot designs and randomised complete block design

open access: yes, 2008
The paper shows, how incomplete split-plot designs can be constructed from -designs and how they can be analysed. The incomplete split-plot design can be regarded as both a practical and statistical compromise between traditional split-plot design and ...
Bigongiali, Federica   +2 more
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Minimum aberration two-level split-plot designs

open access: yes, 1995
In this thesis a certain aspect of fractionated two-level split-plot designs is associated with a subset of the 2 \u27k fractional factorial designs.
Huang, Peng
core  

Split-plot designs: What, why, and how [PDF]

open access: yes, 2009
The past decade has seen rapid advances in the development of new methods for the design and analysis of split-plot experiments. Unfortunately, the value of these designs for industrial experimentation has not been fully appreciated.
Bradley Jones, Christopher J. Nachtsheim
core  

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