Results 101 to 110 of about 621,908 (253)

Some statistical aspects of the planning of non-orthogonal experiments of split-split-plot type

open access: yes, 2014
Celem pracy jest zaprezentowanie pewnej metody konstrukcji układów niekompletnych typu split-split-plot dla doświadczeń nieortogonalnych z co najmniej trzema czynnikami. W literaturze znanych jest wiele metod konstrukcji układów niekompletnych.
Ambroży-Deręgowska, Katarzyna   +1 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

D-optimal design of split-split-plot experiments

open access: yes
In industrial experimentation there is growing interest in studies that span more than one processing step. Convenience often dictates restrictions in randomization in passing from one processing step to another.
GOOS, Peter, BRADLEY, Jones
core  

Selecting optimal follow-up split-plot designs

open access: yes, 2019
Split-plot designs and follow-up designs have been considered in literature for many years. However, no research has been done on selecting optimal follow-up split-plot designs for response surface methodology. In this thesis, we will find optimal follow-
Yang, Bowei
core  

COMPARING ANALYSES OF UNBALANCED SPLIT-PLOT EXPERIMENTS

open access: yes, 2004
Several procedures for constructing confidence intervals and testing hypotheses about fixed effects in unbalanced split-plot experiments have previously been presented and discussed by Remmenga and Johnson.
Dallas E. Johnson   +3 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Tests for the strip-split plot design

open access: yes, 2016
In this article we present the structure of the F tests, the variance components and the approximate degrees of freedom for each of the eight possible mixed models of the strip-split plot design.
Díaz-Pachón, Daniel   +2 more
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Comparison of the Optimal Design: Split-Plot Experiments

open access: yes, 2012
Over the past decade, there have been rapid advances in the development of methods for the design and analysis of optimal split-plot experiment. Industrial experimentation involving optimality criteria has not been fully exhausted.
Francis, Ogege Ikhata, Mbegbu, Julian
core  

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