Results 71 to 80 of about 247,484 (281)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Improved quality of SC magazine paper through enhanced fibre development using the ATMP process [Elektronisk resurs] [PDF]

open access: yes, 2012
A pilot scale refining trial was conducted using the ATMP (Advanced Thermomechanical Pulp) refining concept with White spruce as raw material. Low-intensity TMP and high-intensity TMP with mechanical pre-treatment of chips were compared to ATMP (Mg+P ...
Gorski, Dmitri,, Hill, Jan,
core  

Effects of Different Conditions of Water Cooling at High Temperature on the Tensile Strength and Split Surface Roughness Characteristics of Hot Dry Rock

open access: yesAdvances in Civil Engineering, 2020
To investigate the effects of the different conditions of water cooling at high temperature on the tensile strength and split surface roughness characteristics of hot dry rock in the Songliao Basin, the physical characteristics, tensile strength, and ...
Hanbo Cui, Jupeng Tang, Xintong Jiang
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Fast and fair split computing for accelerating deep neural network (DNN) inference

open access: yesICT Express
Conventional split computing approaches for AI models that generate large outputs suffer from long transmission and inference times. Due to the limited resources of the edge server and selfish MDs, some MDs cannot offload their tasks and sacrifice their ...
Dongju Cha   +3 more
doaj   +1 more source

Determination of Soil and Plant Water Balance and Its Critical Stages for Rainfed Wheat Using Crop Water Stress Index (CWSI)

open access: yesمجله آب و خاک, 2014
In order to determination of water stress threshold and dryland wheat genotypes water status in different nitrogen managements, this experiment was carried out in split split plot RCBD design in three replications in 2010-2011 cropping year.
V. Feiziasl   +4 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

DEVELOPMENT OF COGNITIVE LEARNING SCALE TO TEST THE KNOWLEDGE OF LIVESTOCK OWNERS ABOUT VACCINATION AGAINST THE CONTAGIOUS DISEASES [PDF]

open access: yesJournal of Veterinary and Animal Sciences, 1996
Seventy six items were initially constructed on the basis of promoting thinking rather than rote memorisation to differentiate the. well informed livestock owners from the poorly informed ones.
A. Goswami, R.L. Sagar
doaj  

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