Results 111 to 120 of about 392,166 (257)

Detecting Differential Item and Step Functioning with Rating Scale and Partial Credit Trees [PDF]

open access: yes, 2014
Several statistical procedures have been suggested for detecting differential item functioning (DIF) and differential step functioning (DSF) in polytomous items.
Zeileis, Achim   +2 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

The effect of varying the split-ratio in two-contact semiconductor lasers: an experimental approach

open access: yes, 2003
The effect of the split ratio on bandwidth enhancement for two-contact lasers is investigated experimentally. It is found that with a split ratio of 7:1, a bandwidth enhancement of 36% is achievedThe effect of the split ratio on bandwidth enhancement for
Cryan, MJ   +4 more
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Numerical simulation of liquid sloshing in LNG tanks using a compressible two-fluid flow model

open access: yes, 2009
In this investigation the Reynolds-Averaged Navier-Stokes (RANS) equations are modified to account for variable density and viscosity of the two-fluids flow (i.e. water-air), assuming both fluids compressible.
Chen, Y.G., Temarel, P., Price, W.G.
core  

影响功率分流无级变速器效率的主要参数研究

open access: yesJixie chuandong, 2014
Two classic ways of working of the hydra-mechanical power split CVT are studied.The efficiency formula of power-split is derived by definition,the power split ratio is studied,and the influence of different parameters on system efficiency is analyzed.The
韩梅梅, 高翔
doaj  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Fractures of distal radius in Clinical hospital centre Split in 2014 [PDF]

open access: yes, 2015
CILJ ISTRAŽIVANJA Ciljevi ove retrospektivne studije su ustanoviti broj, spol i dob pacijenata s prijelomima distalnog dijela palčane kosti, njihovo prebivalište, incidenciju u Splitskodalmatinskoj županiji, incidenciju po dobnim skupinama, koliko ih se ...
Gavrilović, Vlado
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

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