Results 101 to 110 of about 1,509,952 (299)

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Radiative Neutralino Decay in Split Supersymmetry

open access: yes, 2009
Radiative neutralino decay $\chi^0_2 -> \chi^0_1\gamma$ is studied in a Split Supersymmetric scenario, and compared with mSUGRA and MSSM. This 1-loop process has a transition amplitude which is often quite small, but has the advantage of providing a very
A. Djouadi   +13 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Bimodal AGNs in Bimodal Galaxies

open access: yes, 2007
By their star content, the galaxies split out into a red and a blue population; their color index peaked around u-r=2.5 or u-r=1, respectively, quantifies the ratio of the blue stars newly formed from cold galactic gas, to the redder ones left over by ...
A. Cavaliere   +6 more
core   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Pertumbuhan Earning Per Share, Price To Book Value dan Price Earning Ratio Sebagai Dasar Keputusan Stock Split

open access: yesJurnal Manajemen dan Wirausaha, 2011
The objective of this research is to examine the effect of earning per share, price to book value and price earning ratio on firms stock split. According to signaling hypothesis, stock split decision can be proxies with the growth of earning per share ...
Djoni Budiardjo, Joshe Hana Hapsari
doaj  

Kinematical structure of the circumstellar environments of galactic B[e]-type stars

open access: yes, 2003
High resolution line profiles are presented for selected forbidden and permitted emission lines of a sample of galactic B[e]-type stars. The spectral resolution corresponds to 5-7 km/s with the exception of some line profiles which were observed with a ...
Acker   +75 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Dehydration Performance of a Compact Electrostatic Separator for High Water-Cut Oil Emulsions

open access: yesShiyou jixie
Compact electric field demulsification separation technology is an effective solution to the challenges of large footprint and low operational efficiency associated with conventional crude oil dehydration equipment on offshore platforms.
Shi Yi   +6 more
doaj  

Single-stage experimental evaluation of tandem-airfoil rotor and stator blading for compressors, part 8 [PDF]

open access: yes
An experimental investigation was conducted with an 0.8 hub/tip ratio, single-stage, axial flow compressor to determine the potential of tandem-airfoil blading for improving the efficiency and stable operating range of compressor stages.
Brent, J. A., Clemmons, D. R.
core   +1 more source

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