Results 91 to 100 of about 1,509,952 (299)

Trade-off between training and testing ratio in machine learning for medical image processing [PDF]

open access: yesPeerJ Computer Science
Artificial intelligence (AI) and machine learning (ML) aim to mimic human intelligence and enhance decision making processes across various fields. A key performance determinant in a ML model is the ratio between the training and testing dataset.
Muthuramalingam Sivakumar   +2 more
doaj   +2 more sources

Exact closed-form expressions for the performance of the split-symbol moments estimator of signal-to-noise ratio [PDF]

open access: yes
Previously, the performance of the split-symbol moments estimator (SSME) of signal-to-noise ratio (SNR) has been evaluated by means of approximate expressions for the estimator mean and variance.
Dolinar, S.
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Better than a lens -- Increasing the signal-to-noise ratio through pupil splitting

open access: yes, 2022
Lenses are designed to fulfill Fermats principle such that all light interferes constructively in its focus, guaranteeing its maximum concentration. It can be shown that imaging via an unmodified full pupil yields the maximum transfer strength for all ...
Becker, Jan   +6 more
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

New insights into the formation of the blue main sequence in NGC 1850

open access: yes, 2018
Recent discoveries of bimodal main sequences (MSs) associated with young clusters (with ages $\lesssim 1$ Gyr) in the Magellanic Clouds have drawn a lot of attention.
de Grijs, Richard   +4 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Analysis of main dynamic parameters of split power transmission [PDF]

open access: yesTransport, 2008
The review carried out had shown one basic approach of split power transmission to the organization of drive which is applied to stepless transmissions of tractors and parallel hybrid cars.
Algirdas Janulevičius   +1 more
doaj   +1 more source

Global Frobenius Betti numbers and F-splitting ratio

open access: yes, 2018
31 ...
De Stefani, Alessandro   +2 more
openaire   +2 more sources

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