Results 51 to 60 of about 33,516 (232)

Status and future of recombinant adeno‐associated virus vector manufacturing

Biotechnology Progress, EarlyView.
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley   +1 more source

Helicoverpa armigera nucleopolyhedrovirus occlusion-derived virus-associated protein, HA100, affects oral infectivity in vivo but not virus replication in vitro [PDF]

, 2011
ORF100 (ha100) of Helicoverpa armigera nucleopolyhedrovirus (HearNPV) has been reported as one of the unique genes of group II alphabaculoviruses encoding a protein located in the occlusion-derived virus (ODV) envelope and nucleocapsid.
Xushi Xu, Luo, S., Just M. Vlak, Fei Deng, Xu, X., Wang, H., Vlak, J.M., Deng, F., Zhang, Y., Yanfang Zhang, Marcel Westenberg, Sijiani Luo, Westenberg, M., Hu, Z., Hualin Wang, Zhihong Hu   +15 more
core   +1 more source

Baculovirus-Based Biocontrol: Synergistic and Antagonistic Interactions of PxGV, PxNPV, SeMNPV, and SfMNPV in Integrative Pest Management

Viruses
The use of chemical pesticides in agriculture has led to the development of resistant pest populations, posing a challenge to long-term pest management.
Alberto Margarito García-Munguía, Carlos Alberto García-Munguía, Paloma Lucía Guerra-Ávila, Estefany Alejandra Sánchez-Mendoza, Fabián Alejandro Rubalcava-Castillo, Argelia García-Munguía, María Reyna Robles-López, Luis Fernando Cisneros-Guzmán, María Guadalupe Martínez-Alba, Ernesto Olvera-Gonzalez, Raúl René Robles-de la Torre, Otilio García-Munguía   +11 more
doaj   +1 more source

Impact of single‐use bioreactor bag materials on Spodoptera frugiperda cell expansion for recombinant adeno‐associated virus manufacturing

Biotechnology Progress, EarlyView.
Abstract Recombinant adeno‐associated virus production for gene therapy applications commonly relies on the Spodoptera frugiperda 9 (Sf9) baculovirus infection platform. The process encompasses cell expansion from flasks through intermediate‐scale bioreactors to large‐scale production.
Min Tae Park, Seyed Pouria Motevalian
wiley   +1 more source

The evolutionary process of invasion in the fall armyworm (Spodoptera frugiperda)

Scientific Reports, 2022
AbstractThe fall armyworm (FAW; Spodoptera frugiperda) is one of the major agricultural pest insects. FAW is native to the Americas, and its invasion was first reported in West Africa in 2016. Then it quickly spread through Africa, Asia, and Oceania, becoming one of the main threats to corn production.
Yainna, Sudeeptha, Tay, Wee Tek, Durand, Karine, Fiteni, Estelle, Hilliou, Frédérique, Legeai, Fabrice, Clamens, Anne-Laure, Gimenez, Sylvie, Asokan, R., Kalleshwaraswamy, C., Deshmukh, Sharanabasappa, Meagher Jr., Robert, Blanco, Carlos, Silvie, Pierre, Brévault, Thierry, Dassou, Anicet, Kergoat, Gael, Walsh, Thomas, Gordon, Karl, Nègre, Nicolas, d'Alençon, Emmanuelle, Nam, Kiwoong   +21 more
openaire   +6 more sources

Potential Distribution and Niche Differentiation of Spodoptera frugiperda in Africa [PDF]

Insects, 2020
The fall armyworm, Spodoptera frugiperda (J.E. Smith) is a serious agricultural pest. The species originates from the tropical and subtropical regions of the Americas and has now become established in many countries. Its strong migratory ability is the key factor in the rapidly expanding range of S.
Jingyu Fan, Pengxiang Wu, Tianqi Tian, Qilin Ren, Muhammad Haseeb, Runzhi Zhang   +5 more
openaire   +3 more sources

Inhibition of Spodoptera frugiperda phenoloxidase activity by the products of the Xenorhabdus rhabduscin gene cluster.

PLoS ONE, 2019
We evaluated the impact of bacterial rhabduscin synthesis on bacterial virulence and phenoloxidase inhibition in a Spodoptera model. We first showed that the rhabduscin cluster of the entomopathogenic bacterium Xenorhabdus nematophila was not necessary ...
Maria Eugenia Nuñez-Valdez, Anne Lanois, Sylvie Pagès, Bernard Duvic, Sophie Gaudriault   +4 more
doaj   +1 more source

Expression, Purification, and Microscopy‐Based Assays for Engineered Recombinant Tyrosinated, Detyrosinated, and Δ2 Human Tubulin

Cytoskeleton, EarlyView.
ABSTRACT Microtubules are noncovalent polymers assembled from α/β tubulin dimers. Their structure, dynamics and interaction with effectors are regulated through the expression of diverse tubulin isotypes and chemically diverse posttranslational modifications, also known as the “tubulin code.” Understanding the biophysical correlates between tubulin ...
Jiayi Chen, Agnieska Szyk, Antonina Roll‐Mecak   +2 more
wiley   +1 more source

Effects of three different host plants on two sex life table parameters of the fall armyworm Spodoptera frugiperda

Scientific Reports
The fall armyworm Spodoptera frugiperda (Lepidoptera: Noctuidae) is a major phytophagous pest that invaded China in late 2018, posing a serious threat to local agricultural production.
Zhao Wang, Huan Zhu, Dao-Chao Jin, Jin-Ting Hou, Xia Liu   +4 more
doaj   +1 more source

Soil‐derived, gut‐dominant generalist bacteria shape the fitness of folivorous larvae

iMeta, EarlyView.
Whether Lepidoptera harbor a conserved core gut microbiome has long remained contentious. Through large‐scale microbiome profiling of folivorous larvae, their host plants, and associated soils across three climatically distinct regions of China, we identify two soil‐derived generalist bacteria, Ralstonia insidiosa and Delftia sp., that colonize 97.92 ...
Yu‐xuan Zheng, Ying Wang, Xiao‐man Zhang, Qian Jin, Yan Zhang, Gui‐fang Wang, Yong‐qi Shao, Jing Li, Cheng Sun, Wei‐dong Kong, Cai‐qing Yang, Ai‐bing Zhang   +11 more
wiley   +1 more source