HMG-Coenzyme A Reductase as a Drug Target for the Prevention of Ankylosing Spondylitis
Frontiers in Cell and Developmental Biology, 2021 Statins are an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR). Growing evidence indicates that statins may have an anti-inflammatory effect.
Zhenyu Zhong +8 more
doaj +1 more source
Common MIR146A Polymorphisms in Chinese Ankylosing Spondylitis Subjects and Controls. [PDF]
PLoS ONE, 2015 Common polymorphisms of microRNA gene MIR146A were reported as associated with different autoimmune diseases, include systemic lupus erythematosus, psoriatic arthritis, asthma and ankylosing spondylitis.
Zhenmin Niu +5 more
doaj +1 more source
Clinical and MRI responses to etanercept in early non-radiographic axial spondyloarthritis : 48-week results from the EMBARK study [PDF]
, 2015 Objective: To evaluate the efficacy and safety of etanercept (ETN) after 48 weeks in patients with early active non-radiographic axial spondyloarthritis (nr-axSpA).
Bonin, Randi +15 more
core +1 more source
Ankylosing Spondylitis: a trade Off of HLA-B27, ERAP, and pathogen interconnections? Focus on Sardinia [PDF]
, 2019 The frequency of HLA-B27 in patients with Ankylosing Spondylitis (AS) is over 85%. There are more than 170 recognized HLA-B27 alleles but the majority of them is not sufficiently represented for genetic association studies.
Cauli, A +5 more
core +2 more sources
Co-Occurrence and Characteristics of Patients With Axial Spondyloarthritis Who Meet Criteria for Fibromyalgia : Results From a UK National Register [PDF]
, 2017 The British Society for Rheumatology (BSR) Biologics Register in Ankylosing Spondylitis is funded by the BSR and they have receive funds for this from Pfizer, AbbVie and UCB.
Atzeni, Fabiola +8 more
core +2 more sources
Treating spondyloarthritis, including ankylosing spondylitis and psoriatic arthritis, to target: recommendations of an international task force [PDF]
, 2013 Background: Therapeutic targets have been defined for diseases like diabetes, hypertension or rheumatoid arthritis and adhering to them has improved outcomes. Such targets are just emerging for spondyloarthritis (SpA). Objective: To define the treatment
Baraliakos, Xenofon +31 more
core +2 more sources
Clinical study of patient with Ankylosing Spondylitis
Journal of Pharmacopuncture, 2006 Object : This study is designed in order to evaluate oriental medical treatment of ankylosing spondylitis. Methods : The authors observed patient by ROM & VAS for operated acupuncture treatment, herbal medicine treatment and physiotherapy Conclusion :
Lee Jae-Min, Hong Kwon-eui
doaj +1 more source
Physical activity and sedentary behaviour and their associations with clinical measures in axial spondyloarthritis [PDF]
, 2019 Engaging in physical activity (PA) is a key aspect in the management of axial spondyloarthritis (axial SpA), however, its relationship with clinical measures is unknown.
Cameron, Sara +4 more
core +3 more sources
Level of adherence to prescribed exercise in spondyloarthritis and factors affecting this adherence: a systematic review [PDF]
, 2019 Adherence is a primary determinant of the effectiveness of any intervention. Exercise is considered essential in the management of spondyloarthritis (SpA); however, the overall adherence to exercise programmes and factors affecting adherence are unknown.
Coulter, EH +4 more
core +2 more sources
Clinics, 2007 PURPOSE: To translate and adapt the Bath Ankylosing Spondylitis Methodology Index (BASMI) - a metrological measurement for the assessment of patients with ankylosing spondylitis to Brazilian-Portuguese and to analyze the applicability of the ...
Samuel Katsuyuki Shinjo +3 more
doaj +1 more source