Results 31 to 40 of about 38,444 (174)

Serum Fetuin-A Level in Patients With Ankylosing Spondylitis and its Relationship With Clinical Parameters

The Turkish Journal of Gastroenterology, 2015
Objectives: This study aims to investigate the association of serum fetuin-A levels with disease activation and clinical parameters in ankylosing spondylitis (AS) patients. Patients and methods: Forty-seven AS patients (30 males, 17 females; mean age
Ferhat GÖKMEN, Ayla AKBAL, Fahri GÜNEŞ, Hakan TÜRKÖN, Ahmet VURAL, Emine BİNNETOĞLU, Erkam KÖMÜRCÜ, Hacer ŞEN Mehmet AŞIK, Erdem AKBAL   +8 more
doaj  

Combination Therapy in Participants With Active Psoriatic Arthritis Using Subcutaneous Guselkumab and Golimumab: Week 24 Results From a Phase 2a, Multicenter, Randomized, Double‐Blind, Proof‐of‐Concept Study

Arthritis &Rheumatology, EarlyView.
Objective To assess guselkumab + golimumab combination therapy versus guselkumab monotherapy in participants with active psoriatic arthritis (PsA) and inadequate response to tumor necrosis factor inhibitors (TNFi‐IR). Methods Adults with active TNFi‐IR PsA (three or more tender/swollen joints) were randomized (2:1) to subcutaneous guselkumab (100 mg) +
Jose U. Scher, Iain B. McInnes, Enrique R. Soriano, Joseph F. Merola, Paul Bird, Vinod Chandran, Edaire Cheng, Elena Reynoso, Warner Chen, Maoji Li, Lianne S. Gensler, Philip J. Mease, Christopher T. Ritchlin   +12 more
wiley   +1 more source

Identifying Systemic Lupus Erythematosus From Serum Proteomic Profiles Using Machine Learning and Genetic Risk Stratification

Arthritis &Rheumatology, EarlyView.
Objective Proteome‐wide risk models for lupus remain underexplored. We developed classification models to identify lupus from serum proteomic profiles. Methods Patients with lupus and individuals with other autoimmune diseases in the UK Biobank were included.
Mehmet Hocaoǧlu, Jishnu Das, Amr H. Sawalha   +2 more
wiley   +1 more source

High‐Resolution Deep Learning Dixon Magnetic Resonance Imaging of the Sacroiliac Joints Is Noninferior to Standard Magnetic Resonance Imaging in Patients With Suspected Axial Spondyloarthritis

Arthritis &Rheumatology, EarlyView.
Objective To compare the multisequence standard magnetic resonance imaging (sMRI) protocol of the sacroiliac joints with a single high‐resolution deep learning–reconstructed Dixon sequence (DL‐Dixon) in patients with suspected axial spondyloarthritis (axSpA). Methods Seventy‐six patients with chronic low back pain and suspected axSpA underwent clinical,
Dominik Deppe, Mariam Koka, Fabian Proft, Sevtap Tugce Ulas, Kay‐Geert Hermann, Denis Poddubnyy, Mikhail Protopopov, Henriette Baum, Hildrun Haibel, Mehrgan Shahryari, Valeria Rios Rodriguez, Jens Vogel‐Claussen, Torsten Diekhoff   +12 more
wiley   +1 more source

The Effect of Anti-Tumor Necrosis Factor-Alpha Treatment on Muscle Performance and Endurance in Patients With Ankylosing Spondylitis: A Prospective Follow-Up Study

The Turkish Journal of Gastroenterology, 2017
Objectives: This study aims to evaluate muscle performance by using isokinetic dynamometer before and at third month of anti-tumor necrosis factor-alpha treatment in ankylosing spondylitis patients. Patients and methods: Thirty ankylosing spondylitis
Musa DEMİRKAPI, Mustafa Turgut YILDIZGÖREN, Hayal GÜLER, Ayşe Dicle TURHANOĞLU   +3 more
doaj  

Coexistence of ankylosing spondylitis and discoid lupus: A case report

İstanbul Kuzey Klinikleri, 2019
Coexistence of ankylosing spondylitis with connective tissue diseases is very rare. Here, in this study, we describe a coexistence of ankylosing spondylitis and discoid lupus erythematosus in a 35-year-old man.
Ayşe Ünal Enginar, Hakan Nur, Cahit Kacar   +2 more
doaj   +1 more source

Determinants of Difficult‐to‐Manage and Treatment‐Refractory Axial Spondyloarthritis: A Cross‐Sectional Analysis Within a Longitudinal Cohort

Arthritis &Rheumatology, EarlyView.
Objective The purpose of this study was to estimate the prevalence of difficult‐to‐manage (D2M) and treatment‐refractory (TR) axial spondyloarthritis (axSpA) and to identify factors associated with D2M and TR disease in a longitudinal cohort. Methods We performed a cross‐sectional analysis on data from the Schroeder Arthritis Institute Spondylitis ...
Patricia Remalante‐Rayco, Laura Passalent, Tina Chim, Hannah Vijayan, Manal Alnasser, Zeynep Baskurt, Robert D. Inman, Nigil Haroon, Denis Poddubnyy   +8 more
wiley   +1 more source

Factors affecting employment in Japanese patients with ankylosing spondylitis (AS)

BMC Rheumatology
Background Ankylosing spondylitis (AS) often affects individuals during their most productive working years. However, few studies have investigated factors influencing employment in Japanese AS patients.
Hoshiko Furusawa, Kurisu Tada, Eri Hayashi, Hisashi Inoue, Shigeto Kobayashi, Ken Yamaji, Naoto Tamura   +6 more
doaj   +1 more source

Ankylosing Spondylitis and Balance

Eurasian Journal of Medicine, 2019
Ankylosing spondylitis is a chronic inflammatory disease that mainly affects axial joints and the changes in the vertebrae cause typical kyphotic posture.
Alper Uckun, Ilhan Sezer
doaj   +1 more source

T cells, the Next Big Target in Axial Spondyloarthritis?

Arthritis &Rheumatology, EarlyView.
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by complex immune dysregulation, with T cells playing a central role in its pathogenesis. In this review, we synthesize current knowledge on diverse T cell subsets in axSpA, their pathogenic mechanisms, and emerging therapeutic strategies targeting these cells. We highlight
Mansi K. Aparnathi, Nigil Haroon
wiley   +1 more source