Results 21 to 30 of about 23,680 (207)

A comparison of three methods to generate a conceptual understanding of a disease based on the patients’ perspective

Journal of Patient-Reported Outcomes, 2017
Background The Food and Drug Administration patient-reported outcome (PRO) guidance provides standards for PRO development, but these standards bring scientific and logistical challenges which can result in a lengthy and expensive instrument development ...
Louise Humphrey, Thomas Willgoss, Andrew Trigg, Stephanie Meysner, Mary Kane, Sally Dickinson, Helen Kitchen   +6 more
doaj   +1 more source

Biomarkers of response to therapy in Ankylosing Spondylitis [PDF]

, 2013
Ankylosing Spondylitis (AS) is a chronic inflammatory disorder of the spine which leads to progressive spinal fusion and deformity. With improvements in MRI, this condition is now being recognized earlier.
Pathan, Ejaz Mohammed Ishaq
core   +1 more source

Evaluation of serum paraoxonase and arylesterase activities in ankylosing spondylitis patients

Clinics, 2010
OBJECTIVES: The aim of this study was to investigate the activities of serum paraoxonase and arylesterase in patients with ankylosing spondylitis with respect to those of healthy controls, to assess whether these enzyme levels are related to disease ...
Fazile Hatipoglu Erdem, Saliha Karatay, Kadir Yildirim, Ahmet Kiziltunc   +3 more
doaj   +1 more source

Persistent clinical efficacy and safety of anti-tumour necrosis factor \textgreeka therapy with infliximab in patients with ankylosing spondylitis over 5 years: evidence for different types of response [PDF]

, 2008
Background: There is insufficient evidence for the long-term efficacy and safety of anti-tumour necrosis factor therapy in patients with ankylosing spondylitis (AS).
Baraliakos, X., Sieper, J., Zeidler, H., Braun, J., Listing, J., Schewe, Stefan, Burmester, G., Sörensen, H., Krause, A., Schneider, M., Fritz, C., Alten, R.   +11 more
core   +1 more source

Discovery of fecal microbial signatures in patients with ankylosing spondylitis

The Turkish Journal of Gastroenterology, 2023
Objectives: This study aimed to investigate the characteristics of the gut microbiota in Chinese patients with ankylosing spondylitis (AS) and healthy controls in Quanzhou aiming to explore the correlation between microbiome changes and AS activities.
Yuquan You, Wei Zhang, Meimei Cai, Qingxin Guo, Jiawen Wang, Yaping Cai, Junsheng Lin   +6 more
doaj  

Whole body MR imaging in ankylosing spondylitis: a descriptive pilot study in patients with suspected early and active confirmed ankylosing spondylitis

BMC Musculoskeletal Disorders, 2007
Background Ankylosing spondylitis is a chronic inflammatory rheumatic disorder which usually begins in early adulthood. The diagnosis is often delayed by many years.
Hodler Juerg, Kissling Rudolf O, Pfirrmann Christian WA, Weber Ulrich, Zanetti Marco   +4 more
doaj   +1 more source

The effect of three years of TNF alpha blocking therapy on markers of bone turnover and their predictive value for treatment discontinuation in patients with ankylosing spondylitis: a prospective longitudinal observational cohort study [PDF]

, 2012
INTRODUCTION: The aim of this study was to investigate the effect of three years of tumor necrosis factor-alpha (TNF-alpha) blocking therapy on bone turnover as well as to analyze the predictive value of early changes in bone turnover markers (BTM) for ...
Eveline van der Veer, Anneke Spoorenberg, Arends, S., Houtman, P.M., Cees G.M. Kallenberg, Leijsma, M.K., Brouwer, E., Reinhard Bos, Elisabeth Brouwer, Kallenberg, C.G., Martha K. Leijsma, Groen, H., Groen, H.; id_orcid, van der Veer, E., Bos, R., Spoorenberg, A., Henk Groen, Suzanne Arends, Pieternella M. Houtman   +18 more
core   +2 more sources

Quantitative metagenomics reveals unique gut microbiome biomarkers in ankylosing spondylitis

Genome Biology, 2017
Background The assessment and characterization of the gut microbiome has become a focus of research in the area of human autoimmune diseases. Ankylosing spondylitis is an inflammatory autoimmune disease and evidence showed that ankylosing spondylitis may
Chengping Wen, Zhijun Zheng, Tiejuan Shao, Lin Liu, Zhijun Xie, Emmanuelle Le Chatelier, Zhixing He, Wendi Zhong, Yongsheng Fan, Linshuang Zhang, Haichang Li, Chunyan Wu, Changfeng Hu, Qian Xu, Jia Zhou, Shunfeng Cai, Dawei Wang, Yun Huang, Maxime Breban, Nan Qin, Stanislav Dusko Ehrlich   +20 more
doaj   +1 more source

ASAS/EULAR recommendations for the management of ankylosing spondylitis [PDF]

, 2006
Objective: To develop evidence based recommendations for the management of ankylosing spondylitis (AS) as a combined effort of the `ASsessment in AS' international working group and the European League Against Rheumatism.Methods: Each of the 22 ...
Sieper, J., Sturrock, R.D., Böhm, H., van Royen, B. J., Pavelka, K, Inman, R.D., Burgos-Vargas, R., Géher, P., Collantes, E, Braun, J., Kvien, TK, Davis Jr., J. C., Kvien, T.K., Leirisalo-Repo, M., Stucki, G., Khan, M.A., Geher, P, Davis, JC, Dijkmans, B., Pavelka, K., Sturrock, RD, Davis, J. C., Stucki, G, van der Heijde, D., Kvien, T. K., Zochling, J., Olivieri, I., Dougados, M, Leirisalo-Repro, M, Wendling, D., Dougados, M., Inman, R. D., Burgos-Vargas, R, Sieper, J, Collantes, E., Dijkmans, B, Olivieri, I, Bohm, H, Zo, Khan, MA, van der, LS, van Royen, BJ, Renseigné, Non, van der, HD, Khan, M. A., Wendling, D, Inman, RD, van der Linden, S., Braun, J, Zo,, Géher, R. D. and Khan, Sturrock, R. D.   +51 more
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ASAS/WHO ICF Core Sets for ankylosing spondylitis (AS): how to classify the impact of AS on functioning and health [PDF]

, 2010
Objective: To report on the results of a standardised consensus process agreeing on concepts typical and/or relevant when classifying functioning and health in patients with ankylosing spondylitis (AS) based on the International Classification of ...
Stucki, Gerold, van der Horst Bruinsma, I. E., Kostanjsek, Nenad, Maksymowych, W.P., Maksymowych, W., Boonen, A., Braun, J., Bruinsma, I.E.V., Huang, F., Cieza, A., van der Horst Bruinsma, I.E., van der Heijde, D., Bruinsma, I. E. van der Horst, Heijde, D. van der, Cieza, Alarcos, Kostanjsek, N., Huang, Fan, Stucki, G.   +17 more
core   +1 more source