Results 71 to 80 of about 38,101 (219)

Quantification of paravertebral cross-sectional muscle areas and fatty degeneration and their correlation with clinical parameters in ankylosing spondylitis: a comprehensive analysis [PDF]

ARP Rheumatology
Aims: Ankylosing spondylitis (AS) is a chronic disease characterized by inflammation of the spine and joints. This study aimed to examine the multifidus (MF) and erector spinae (ES) muscles in AS patients using magnetic resonance imaging (MRI), and to ...
Selçuk Akkaya, Gonca Sağlam Akkaya, Serpil Demirulus, Hanife Baykal Şahin, Gamze Kılıç, Erhan Çapkın, Murat Karkucak   +6 more
doaj  

Erectile dysfunction in ankylosing spondylitis patients

International Brazilian Journal of Urology
Background Rheumatic diseases such as ankylosing spondylitis (AS) may be associated with sexual dysfunction. Aim To study erectile function of a group of Brazilian AS patients comparing them with controls.
Thiago Santana, Thelma Skare, Vitor Steil Delboni, Juliana Simione, Ana Paula B. Campos, Renato Nisihara   +5 more
doaj   +1 more source

YTHDF3 Enhances Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells in Osteoporosis by Promoting TBX19 Expression

Cell Proliferation, EarlyView.
In this study, OP‐BMSCs were successfully isolated from OVX osteoporotic rats. Mechanistic investigations revealed that the RNA‐binding protein YTHDF3 significantly upregulates Tbx19 expression by enhancing the stability of Tbx19 mRNA. Elevated Tbx19 levels, in turn, activate key osteogenic molecules, effectively promoting the differentiation of OP ...
Qianke Tao, Qiaonan Ye, Chengpeng Yang, Yuping Xie, Xuemei Long, Long Bai, Zhiyuan Zhang, Qianwei Li, Dan Tan, Jingang Xiao   +9 more
wiley   +1 more source

Quality of life in patients with Ankylosing Spondylitis in Duhok government, Kurdistan of Iraq

Advanced Medical Journal
Background and objectives: Spondylarthritis is a broad spectrum of chronic inflammatory diseases, and one of its of phenotypes is ankylosing spondylitis.
Nahida Zuber Ali, Muhammed Tahir Rasool   +1 more
doaj   +1 more source

Impact of adalimumab treatment on impairment of non‐professional activities in psoriasis patients

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Psoriasis can result in reduced quality of life, work productivity loss, and a significant restriction in non‐professional activities. This study investigates the effects of long‐term treatment with adalimumab regarding work ability, non‐professional activities, and health‐related quality of life in a large real‐word ...
Georgios Kokolakis, Sandra Philipp, Thomas Mosch, Björn Fritz, Robert Sabat   +4 more
wiley   +1 more source

Causal relationship between gut microbiota and ankylosing spondylitis and potential mediating role of inflammatory cytokines: A mendelian randomization study.

PLoS ONE
Associations between gut microbiota and ankylosing spondylitis have been discovered in previous studies, but whether these associations reflect a causal relationship remains inconclusive. Aiming to reveal the bidirectional causal associations between gut
Xinyu Du, Haibo Li, Hongzhou Zhao, Shuangshuang Cui, Xiaozhuo Sun, Xiaochan Tan   +5 more
doaj   +1 more source

A Phase 2 Trial of Frexalimab, a CD40L Antagonist, in Adolescents and Adults With Recent‐Onset Type 1 Diabetes (FABULINUS): Rationale and Study Design

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Introduction Type 1 diabetes (T1D) is a chronic autoimmune disease, characterised by progressive destruction of the insulin‐producing pancreatic β‐cells. Preserving remaining β‐cells at the time of diagnosis may improve long‐term outcomes. Frexalimab is a humanised monoclonal antibody specific for CD40L undergoing evaluation for treatment of ...
Andriy Cherkas, Baerbel Rotthaeuser, Niels Porksen, Pascale Labard, My‐Liên Nguyên‐Pascal, Mathieu Coudert, Baptiste Berthou, Marie Baccara‐Dinet, Gabor Boka, Mark Peakman, Felix Reschke, Michael J. Haller   +11 more
wiley   +1 more source

Utility of ANA in hospitalized patients with headache and suspected systemic autoimmune disease

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This study evaluates antinuclear antibody (ANA) test performance in identifying rheumatologic conditions as the source of the headache. Background ANA testing is widely used to screen for autoimmune diseases in patients with headaches, but its diagnostic utility remains unclear. Methods In this retrospective analytic, cross‐sectional
Erez Magiel, Melanie Shanie Roitman, Barak Pflantzer, Roni Loebenstein Dagan, Roni Sharon, Abdualla Watad, Nicola Maggio, Saar Anis   +7 more
wiley   +1 more source

Transthoracic Echocardiography findings in patients with Ankylosing Spondylitis in Kurdistan region

Advanced Medical Journal
Background and objectives: Ankylosing spondylitis is a chronic inflammatory disorder that affecting axial and non-axial joints leads to a loss of mobility and function over time.
Elaf Kamal Abdulwahab, Dashty Abbas Albustany   +1 more
doaj   +1 more source

Geographic Variation in Diagnostic Ability and Quality of Care Metrics: A Case Study of Ankylosing Spondylitis and Low Back Pain

Inquiry: The Journal of Health Care Organization, Provision, and Financing, 2017
Studies examining geographic variation in care for low back pain often focus on process and outcome measures conditional on patient diagnosis but generally do not take into account a physician’s ability to diagnose the root cause of low back pain. In our
Jason Shafrin PhD, Jenny Griffith PharmD, Jin Joo Shim MS, Caroline Huber MPH, Arijit Ganguli PhD, MBA, Wade Aubry MD   +5 more
doaj   +1 more source