Results 91 to 100 of about 151,084 (348)

Conformational Plasticity of HLA-B27 Molecules Correlates Inversely With Efficiency of Negative T Cell Selection [PDF]

, 2020
The development of autoimmune disorders is incompletely understood. Inefficient thymic T cell selection against self-peptides presented by major histocompatibility antigens (HLA in humans) may contribute to the emergence of auto-reactive effector cells ...
Loll, Bernhard, Rückert, Christine, Uchanska-Ziegler, Barbara, Ziegler, Andreas   +3 more
core   +1 more source

Prevalence of peripheral and extra-articular disease in ankylosing spondylitis versus non-radiographic axial spondyloarthritis: a meta-analysis

Arthritis Research & Therapy, 2016
BackgroundPeripheral disease (arthritis, enthesitis and dactylitis) and extra-articular disease (uveitis, psoriasis and inflammatory bowel disease) is common in ankylosing spondylitis (AS) and non-radiographic axial spondyloarthritis (nr-axSpA).
J. D. de Winter, L. V. van Mens, D. M. van der Heijde, R. Landewé, D. Baeten   +4 more
semanticscholar   +1 more source

Brucellar Spondylitis

Journal of Korean Neurosurgical Society, 2008
The incidence of Brucellosis is increasing in Korea. Spondylitis is the most frequent complication, but it is difficult to diagnose because its clinical symptoms are non-specific. It should therefore be included in the differential diagnosis of back pain.
Hong Jae, Lee, Jin Woo, Hur, Jong Won, Lee, Sang Rok, Lee   +3 more
openaire   +2 more sources

Mucosal‐Associated Invariant T Cells in Rheumatic Diseases

Arthritis &Rheumatology, EarlyView.
Mucosal‐associated invariant T (MAIT) cells are innate‐like T cells defined by their semi‐invariant T cell receptor and restriction by the major histocompatibility complex class I–related molecule (MR1). These cells are primarily activated by microbial‐derived metabolites presented by MR1 or by cytokines.
Manon Lesturgie‐Talarek, Virginie Gonzalez, Lucie Beaudoin, Noémie Sénot, Corinne Miceli‐Richard, Yannick Allanore, Agnès Lehuen, Jerôme Avouac   +7 more
wiley   +1 more source

Children and adults skeletal complications of Brucellosis

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2003
Background and Objective: Skeletal complications are common in brucellosis. Early diagnosis of these complications may prevent surgical procedures. The aim of this study was to evaluate the skeletal complications of brucellosis in Babol town.
MR Hassanjani Roshan, SM Esmaeilnejad Ganji, M Haji Ahmadi   +2 more
doaj  

Inflammatory bowel disease-specific autoantibodies in HLA-B27-associated spondyloarthropathies: Increased prevalence of ASCA and pANCA [PDF]

, 2004
Aims: An association between inflammatory bowel disease (IBD) and spondyloarthropathies (SpA) has repeatedly been reported. The aim of the present study was to investigate whether serologic markers of IBD, e. g.
Brumberger, V., Folwaczny, Christian, Glas, J., Gruber, R., Kellner, H., Marker-Hermann, E., Strasser, C., Török, H.-P.   +7 more
core   +1 more source

Effect of secukinumab on clinical and radiographic outcomes in ankylosing spondylitis: 2-year results from the randomised phase III MEASURE 1 study

Annals of the Rheumatic Diseases, 2016
Objective To evaluate the effect of secukinumab, an interleukin-17A inhibitor, on clinical signs and symptoms and radiographic changes through 2 years in patients with ankylosing spondylitis (AS).
J. Braun, X. Baraliakos, A. Deodhar, D. Baeten, J. Sieper, P. Emery, A. Readie, R. Martin, S. Mpofu, H. Richards   +9 more
semanticscholar   +1 more source

Rehabilitation interventions delivered via telehealth to support self‐management of rheumatic and musculoskeletal disease: A scoping review

Arthritis &Rheumatology, Accepted Article.
Objective To identify and summarize existing telerehabilitation interventions for people living with RMDs, including the rehabilitation components, the technology used, the type of health care professional (HCP) interaction, and how the effectiveness is evaluated.
Thomas A Ingram, Rosemarie Barnett, Nuzhat Shakaib, Simon Jones, Raj Sengupta, Peter C Rouse   +5 more
wiley   +1 more source

Brucellaspondylodiscitis and Paravertebral Abscess with Negative Serology: A Case Report

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2012
Background and Objectives: Brucellosis is a common zoonosis which still remains as a major health problem in certain parts of the world. Osteoarticular involvement is the most frequent complication of brucellosis, in which the diagnosis of ...
AA Farazi, F Didgar, AR Ghandi, M Soofian   +3 more
doaj  

Comorbidity in patients with HIV infection and tuberculous spondylitis as a risk factor for infectious complications

Хирургия позвоночника, 2020
Objective. To determine how the presence of comorbidity, including the fact of the presence of HIV infection, affects the risks of developing infectious postoperative complications in patients with tuberculous spondylitis. Material and Methods.
Evgeniya V. Shuvalova, Arkady A. Vishnevskiy   +1 more
doaj   +1 more source